Risperidone oral solution versus standard tablets for the acute treatment of patients with schizophrenia

►RIS-OS does not show an earlier onset of efficacy than RIS-ST. ►The severity of extrapyramidal symptoms is similar between the groups. ►RIS-OS induces less prolactin increase than RIS-ST in drug-naïve female patients. ►No significant difference in DAI-30 is observed between the two forms.