Antidepressant-like effect of Valeriana glechomifolia Meyer (Valerianaceae) in mice

► V. glechomifolia shows antidepressant-like effect in animal models. ► Sulpiride, SCH 23390 and yohimbine block the anti-immobility V. glechomifolia effect. ► V. glechomifolia potentiates the effect of antidepressants in forced swimming test. ► V. glechomifolia mode of action involves dopaminergic and noradrenergic systems.