5-Methyl phenazine-1-carboxylic acid: A novel bioactive metabolite by a rhizosphere soil bacterium that exhibits potent antimicrobial and anticancer activities

A proposed model for 5-methyl phenazine-1-carboxylic acid (MPCAB)-induced apoptosis in A549 and MDA MB-231 cancer cells. The MPCAB induces apoptosis via down regulation of anti-apoptotic Bcl-2 family proteins and activation of caspase-3.