Comparative protein profile of human hepatoma HepG2 cells treated with graphene and single-walled carbon nanotubes: An iTRAQ-coupled 2D LC-MS/MS proteome analysis

► Proteomics was used to study cellular functions in response to graphene and SWCNTs. ► SWCNTs might induce oxidative stress and lead to apoptosis. ► Graphene appeared to be less toxic and more biocompatible. ► The protein profile is useful to evaluate biocompatibility of graphene and SWCNTs.