Neonatal fluoxetine exposure affects the action potential properties and dendritic development in cortical subplate neurons of rats

► Effects of neonatal exposure of fluoxetine on subplate neurons are examined. ► The coherent growth of structure and function is disrupted by early Flx treatment. ► The rheobase for generating action potential is increased in Flx-exposed rats. ► Dendritic remodeling of SPns is affected by early Flx treatment. ► Numerous short branches are left in SPns of Flx-rats.