Cell death induced by the Alternaria mycotoxin Alternariol

► AOH induced a mitochondrial apoptotic pathway. ► AOH triggered the opening of the mitochondrial permeability transition pore (PTP). ► AOH induced a loss of the mitochondrial transmembrane potential (ΔΨm). ► AOH does not directly target mitochondria. ► Bax is partially involved in AOH-induced mitochondrial apoptosis.