کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6072416 | 1587539 | 2014 | 8 صفحه PDF | دانلود رایگان |
Pemphigus herpetiformis is one of the less common forms of pemphigus, first introduced by JabÅoÅska and colleagues in 1975. This autoimmune bullous disease combines the clinical features of dermatitis herpetiformis and the immunologic characteristics of pemphigus. The target autoantigen is usually desmoglein 1 (or less frequently desmoglein 3), although recently it has become increasingly obvious that patients with pemphigus herpetiformis also demonstrate autoantibodies against desmocollin. Here, we summarize reported cases of pemphigus herpetiformis and describe current knowledge considering epidemiology, clinical manifestations, histologic findings, immunopathology, pathophysiologic concepts, associated diseases, and treatment of this rare disorder.
Journal: Journal of the American Academy of Dermatology - Volume 70, Issue 4, April 2014, Pages 780-787