کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6125830 1221028 2015 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Regulation of stimulus-inducible gene expression in myeloid cells
ترجمه فارسی عنوان
مقررات بیان ژن القاء محرک در سلول های میلوئیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
چکیده انگلیسی
In this review we summarize advances and concepts which have been made towards the understanding of inducible gene expression, with a particular focus on insights gained using the myeloid system as a model. We discuss the emerging concept of layered control of gene regulation and cell identity by different functional classes of transcription factors; and examine recent progress to understanding the molecular processes involved, including the involvement of nucleosome positioning, chromatin modifications, and nuclear architecture. We also address the exciting but less-well understood role of non-coding RNAs in controlling specific gene expression programmes in myeloid and other cell-types.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Immunology - Volume 27, Issue 1, February 2015, Pages 33-43
نویسندگان
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