Antifouling activity of commercial biocides vs. natural and natural-derived products assessed by marine bacteria adhesion bioassay

► Bacterial adhesion and viability used for the screening of new non-toxic antifoulants. ► Commercial, natural and natural-derived products tested on five strains from biofilms. ► Commercial antifoulants TBTO and Sea Nine showed low EC50 but high toxicity. ► Non-commercial products showed anti-adhesion activities together with no toxicity. ► Strains had different response profiles strengthened the need to use several ones.