کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6422978 | 1341240 | 2012 | 11 صفحه PDF | دانلود رایگان |

An eigenvalue problem, the convergence difficulties that arise and a mathematical solution are considered. The eigenvalue problem is motivated by simplified models for the dissociation equilibrium between double-stranded and single-stranded DNA chains induced by temperature (thermal denaturation), and by the application of the so-called transfer integral technique. Namely, we extend the Peyrard-Bishop model for DNA melting from the original one-dimensional model to a three-dimensional one, which gives rise to an eigenvalue problem defined by a linear integral equation whose kernel is not in L2. For the one-dimensional model, the corresponding kernel is not in L2 either, which is related to certain convergence difficulties noticed by previous researchers. Inspired by methods from quantum scattering theory, we transform the three-dimensional eigenvalue problem, obtaining a new L2 kernel which has improved convergence properties.
Journal: Journal of Computational and Applied Mathematics - Volume 236, Issue 15, September 2012, Pages 3561-3571