A microscale method of protein extraction from bacteria: Interaction of Escherichia coli with cationic microparticles

- Cationic microparticles extract recombinant proteins upon contact with E. coli cells.
- Endogenous component concentration in homogenate is three orders of magnitude lower.
- E. coli cells form flocs upon contact with microparticles facilitating separation.
- Selective desorption of bound protein by NaCl without destroying the floc network.