کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6492309 | 43557 | 2007 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Frequency change-induced alternative potential waveform dependence of membrane damage to cells cultured on an electrode surface
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In the present study, alternative potential stimulation with rectangular pulse, sine and triangular waveforms at 10 and 100Â Hz was applied to cells cultured on an ITO electrode. As a result, we found that the alternating potential waveform dependence induced by the frequency on membrane damage of cells cultured on an electrode surface. The cell membrane damage was promoted by a rectangular pulse wave in comparison with sine and triangular waves, when alternating electrical potentials of 0 to +1.0Â V at 100Â Hz were loaded. In contrast, this waveform dependence was not observed when the frequency was 10Â Hz. Furthermore, it was found that cell membrane damage was induced at positive potentials more than +0.8Â V under the present experimental conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biotechnology - Volume 129, Issue 3, 1 May 2007, Pages 498-501
Journal: Journal of Biotechnology - Volume 129, Issue 3, 1 May 2007, Pages 498-501
نویسندگان
Masato Tominaga, Shouichiro Nagaishi, Maiko Kirihara, Etsuko Kumagai, Shinji Harada, Isao Taniguchi,