کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6553848 | 160886 | 2015 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Identifying the most likely contributors to a Y-STR mixture using the discrete Laplace method
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Identifying the most likely contributors to a Y-STR mixture using the discrete Laplace method Identifying the most likely contributors to a Y-STR mixture using the discrete Laplace method](/preview/png/6553848.png)
چکیده انگلیسی
We then used the discrete Laplace method on the remaining data (excluding h1 and h2) to rank the contributor pairs by the product of the contributors' estimated haplotype frequencies. Successful separation of mixtures (defined by the observation that the true contributor pair was among the 10 most likely contributor pairs) was found in 42-52% of the cases for 21 loci, 69-75% for 15 loci and 92-99% for 10 loci or less depending on the dataset and how the discrete Laplace model was chosen. Y-STR mixtures with many loci are difficult to separate, but even haplotypes with 21 Y-STR loci can be separated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Forensic Science International: Genetics - Volume 15, March 2015, Pages 76-83
Journal: Forensic Science International: Genetics - Volume 15, March 2015, Pages 76-83
نویسندگان
Mikkel Meyer Andersen, Poul Svante Eriksen, Helle Smidt Mogensen, Niels Morling,