کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7689943 | 1495901 | 2014 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
UHPLC-MS for the analytical characterization of traditional Chinese medicines
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کلمات کلیدی
UHPLC-MSUltra-high-performance liquid chromatography (UHPLC)Analytical characterization - توصیف تحلیلیIdentification - شناساییTraditional Chinese medicine (TCM) - طب سنتی چینی (TCM)Mass spectrometry (MS) - طیف سنجی جرمی (MS)Phytochemical - فیتوشیمیاییMetabolomics - متابولومیکMetabolite - متابولیتDrug discovery - کشف مواد مخدر
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Traditional Chinese medicine (TCM) has been playing a very important role in health protection and disease control for thousands of years. The therapeutic efficacy of TCMs is based on the combined action of a mixture of phytochemical constituents. Because of the chemical diversity and the dynamic concentration range, analysis of TCMs remains a huge challenge. The large-scale analyses of TCMs are bound to advancements in ultra-high-performance liquid chromatography (UHPLC) technology that have emerged in parallel with the development of mass spectrometry (MS). UHPLC-MS was rapidly accepted by the analytical community and is gradually being applied to TCMs. This review describes the applications of UHPLC-MS in TCM research. We give an overview of the latest applications of UHPLC-MS to natural product analysis in complex TCMs, highlighting its advantages with certain characteristic examples.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: TrAC Trends in Analytical Chemistry - Volume 63, December 2014, Pages 180-187
Journal: TrAC Trends in Analytical Chemistry - Volume 63, December 2014, Pages 180-187
نویسندگان
Xijun Wang, Aihua Zhang, Guangli Yan, Ying Han, Hui Sun,