کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7789692 | 1500641 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The anti-DHAV activities of Astragalus polysaccharide and its sulfate compared with those of BSRPS and its sulfate
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کلمات کلیدی
ALTDMEMMDAVirus controlDVHDEHsCATCMF-PBSDHAVDuck hepatitis A virusNOSSAPs3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide - 3- (4،5-dimethylthiazol-2-yl) -2،5-difenyltetrazolium bromideAPs - AP هاDulbecco's modified Eagle Medium - Eagle Medium اصلاح شده DulbeccoGSH-Px - GSH-PXMTT - MTTAST - آسپارتات ترانس آمینازAspartate aminotransferase - آسپارتات ترانس آمیناز یا AST Alanine aminotransferase - آلانین آمینوترانسفرازALP - آلکالن فسفاتازAlkaline phosphatase - آلکالین فسفاتاز یا فسفاتاز قلیاییSulfated modification - اصلاح سولفاتSOD - سدSuperoxide dismutase - سوکسوکس دیسموتازcalcium and magnesium-free phosphate-buffered saline - فسفات بافر فسفری کلسیم و منیزیم نمکAntiviral activity - فعالیت ضد ویروسیlactate dehydrogenase - لاکتات دهیدروژناز LDH - لاکتات دهیدروژناز به صورت مختصر شده LDH Maintenance medium - متوسط نگهداریComparison - مقایسهnitric oxide synthase - نیتریک اکسید سنتازAstragalus polysaccharide - پلی ساکارید AstragalusCatalase - کاتالازblank control - کنترل خالیcell control - کنترل سلولglutathione peroxidase - گلوتاتیون پراکسیداز
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The anti-DHAV activities of Astragalus polysaccharide and its sulfate compared with those of BSRPS and its sulfate The anti-DHAV activities of Astragalus polysaccharide and its sulfate compared with those of BSRPS and its sulfate](/preview/png/7789692.png)
چکیده انگلیسی
This paper studied the anti-duck hepatitis A virus (DHAV) activities of Astragalus polysaccharide (APS) and its sulfate (sAPS) compared with those of Bush Sophora Root polysaccharide (BSRPS) and its sulfate (sBSRPS). The antiviral activities of APS and sAPS were measured by MTT and real-time PCR methods, in vitro. In vivo experiment, the mortality rate and the evaluation indexes of hepatic injury, peroxidative injury and immune level were measured. Just like the condition of BSRPS and sBSRPS, the anti-DHAV activities of sAPS were stronger than those of APS, both in vitro and in vivo. It indicated sulfated modification could enhance the antiviral ability of polysaccharide. But unlike the antiviral effects of BSPRS and sBSRPS in vivo, APS and sAPS did not reduce the mortality rates as their abilities of scavenging free radicals and alleviating the hepatic injuries were weaker than those of BSRPS and sBSRPS. And they even did not enhance the immune levels.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 117, 6 March 2015, Pages 339-345
Journal: Carbohydrate Polymers - Volume 117, 6 March 2015, Pages 339-345
نویسندگان
Yun Chen, Meiyun Song, Yixuan Wang, Wen Xiong, Ling Zeng, Shuaibing Zhang, Meiyun Xu, Hongxu Du, Jiaguo Liu, Deyun Wang, Yi Wu, Yuanliang Hu,