Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats

► Muscle and liver in rats respond differently to limiting feeding to daylight hours. ► Altered muscle glycogen storage and decreased energy expenditure in day-fed rats. ► Diurnal gene expression and glycogen content shift in liver to mimic food intake. ► Disrupted energy metabolism in day-fed rats predisposes to fat deposition. ► Differences in the response to day-feeding with chow and high fat diet