The association between interleukin polymorphism and recurrent aphthous stomatitis: A meta-analysis

The meta-analysis suggested that the mutation of IL-1beta(−511C/T) in Europe and IL-1beta(+3954C/T) in America tend to increase the risk of RAS, but the polymorphism of IL-10(−1082G/A) appears to have no association with RAS risk in America. Further study is required to confirm the above conclusions.