کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8715921 | 1587875 | 2018 | 25 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
EB2017-Progress in Epidermolysis Bullosa Research toward Treatment and Cure
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کلمات کلیدی
DEBPTCEBsBMTRDEBEpidermolysis bullosa simplex - اپیدرمولیز بیضوی سادهdystrophic epidermolysis bullosa - اپیدرمولیز دیستروفی قلبیJEB - جیبBone marrow transplantation - پیوند مغز استخوانpremature termination codon - کدون از بین بردن زودرسepidermolysis bullosa - گوسفند اپیدرمولیزjunctional epidermolysis bullosa - گوسفند اپیدرمولیز
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
امراض پوستی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Epidermolysis bullosa, a group of heritable blistering disorders, shows extensive phenotypic variability due to mutations in as many as 20 distinct genes. There is no cure for this devastating group of disorders; however, a number of preclinical developments show promise, and some approaches have already reached the stage of early clinical trials. Dystrophic Epidermolysis Bullosa Research Association (DEBRA) International, a global coalition of national patient organizations advocating on behalf of the patients and families with epidermolysis bullosa, supports research and organizes periodic scientific and clinical meetings on this disease. The most recent meeting, EB2017, was held in Salzburg in September 2017. This report summarizes some of the recent research and clinical developments that have identified promising avenues toward treatment and perhaps eventual cure, with improved quality of life for patients with epidermolysis bullosa.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Investigative Dermatology - Volume 138, Issue 5, May 2018, Pages 1010-1016
Journal: Journal of Investigative Dermatology - Volume 138, Issue 5, May 2018, Pages 1010-1016
نویسندگان
Jouni Uitto, Leena Bruckner-Tuderman, John A. McGrath, Rainer Riedl, Clare Robinson,