کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8824378 1610315 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Use of the Woodchuck as an Animal Model for Evaluation of Transarterial Embolization
ترجمه فارسی عنوان
استفاده از وودچاک به عنوان یک مدل حیوانی برای ارزیابی امبولیسم حملونری
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
چکیده انگلیسی
There are many shortcomings of current animal models as surrogates of hepatocellular carcinoma that handicap preclinical testing of embolization agents. The present study explores the feasibility of using the woodchuck (Marmota monax) as an animal model for the testing of novel embolization agents. Four woodchucks underwent magnetic resonance imaging, angiography, and left lobar hepatic artery particle embolization. Percutaneous access, arteriography, and lobar embolization were successful in all animals, with angiographic stasis obtained in the target vessel with minimal reflux of embolic material. These results support the feasibility of the woodchuck as an animal model for preclinical testing of embolization agents.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Vascular and Interventional Radiology - Volume 28, Issue 10, October 2017, Pages 1467-1471
نویسندگان
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