کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8852564 | 1618778 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Prevalence and predictors of phthalate exposure in pregnant women in Charleston, SC
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کلمات کلیدی
ICCDEPdibutyl phthalateDIBPDnBPDMPGSDBBzPPCPMEPDEHPMBPMiBPMBzPNHANESDINCHDBPdi-2-ethylhexyl phthalatedi-n-butyl phthalateNISTMEHPSRMDEHTPMEHHPMMPMEOHPmono(2-ethyl-5-hydroxyhexyl) phthalateDiNP - DINPmono(2-ethyl-5-oxohexyl) phthalate - mono (2-ethyl-5-oxohexyl) phthalatemono(2-ethylhexyl) phthalate - mono (2-ethylhexyl) phthalateSES - آنgeometric standard deviation - انحراف استاندارد هندسیstandard deviation - انحراف معیارPregnancy - بارداریNational Health and Nutrition Examination Survey - بررسی بهداشت و تغذیه ملیbutylbenzyl phthalate - بوتیل بنزیل فتالاتBiomonitoring - بیومونیتوریanalysis of variance - تحلیل واریانسANOVA - تحلیل واریانس Analysis of varianceLOD یا Limit of detection - حد تشخیصMedical University of South Carolina - دانشگاه پزشکی کارولینای جنوبیDiethyl phthalate - دی اتیل فتالاتdiisobutyl phthalate - دی فسفاتیل فتالاتdimethyl phthalate - دی متیل فتالاتdiisononyl phthalate - دیونیزونیل فتالاتbody mass index - شاخص توده بدنBMI - شاخص توده بدنیintraclass correlation coefficient - ضریب همبستگی داخل کلاسیconfidence interval - فاصله اطمینانPhthalate - فتالات، استرهای فتالاتDetection frequency - فرکانس تشخیصlimit of detection - محدودیت تشخیصpersonal care product - محصول مراقبت شخصیendocrine disruptor - مختل کننده غدههای درون ریزREF - مرجعstandard reference material - مرجع استانداردRace - مسابقهmusc - مشکNational Institute of Standards and Technology - موسسه ی ملی استانداردها و تکنولوژیmonoethyl phthalate - مونو اتیل فتالاتmonobenzyl phthalate - مونوبنسیل فتالاتmonobutyl phthalate - مونوبوتیل فتالاتMonomethyl phthalate - مونومیت مالت فتالاتGeometric mean - میانگین هندسیSpecific gravity - وزن مخصوصsocioeconomic status - وضعیت اجتماعی و اقتصادیPVC - پلیوینیل کلراید یا پیویسیPredictor - پیشگوSouth Carolina - کارولینای جنوبیPolyvinyl chloride - کلرید پلی وینیلreference group - گروه مرجع
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
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چکیده انگلیسی
Phthalates are plasticizers commonly detected in human urine due to widespread exposure from PVC plastics, food packaging, and personal care products. Several phthalates are known antiandrogenic endocrine disruptors, which raises concern for prenatal exposure during critical windows of fetal development. While phthalate exposure is ubiquitous, certain demographics are subject to greater or lesser exposure. We sampled urine from 378 pregnant women during the second trimester of gestation living in Charleston, SC, and measured eight urinary phthalate metabolites as biomarkers of phthalate exposure: monobutyl phthalate (MBP), monobenzyl phthalate (MBzP), mono(2-ethylhexyl) phthalate (MEHP), mono(2-ethyl-5-oxohexyl) phthalate (MEOHP), mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), monoethyl phthalate (MEP), monoisobutyl phthalate (MiBP), and monomethyl phthalate (MMP). Demographic data was collected from questionnaires administered at the time of specimen collection. All phthalate metabolites were detected in over 93% of urine samples. On average, concentrations were highest for MEP (median = 47.0 ng/mL) and lowest for MMP (median = 1.92 ng/mL). Sociodemographic characteristics associated with elevated phthalate concentrations included being unmarried, less educated, having a low income, high body mass index (BMI), and/or being African American. After racial stratification, age, BMI, education, and income were significantly associated with phthalate concentrations in African American women. Marital status was associated with phthalate concentrations in Caucasian women only, with greater concentrations of MBP, MEHHP, MiBP, and MMP in unmarried versus married women. Results of this cross-sectional study provide evidence for significant racial and demographic variations in phthalate exposure.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemosphere - Volume 193, February 2018, Pages 394-402
Journal: Chemosphere - Volume 193, February 2018, Pages 394-402
نویسندگان
Abby G. Wenzel, John W. Brock, Lori Cruze, Roger B. Newman, Elizabeth R. Unal, Bethany J. Wolf, Stephen E. Somerville, John R. Kucklick,