کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8959064 | 1646287 | 2018 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Understanding the Emergence of Neuropsychiatric Disorders With Network Neuroscience
ترجمه فارسی عنوان
درک ظهور اختلالات روانپزشکی با علوم اعصاب شبکه
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
Major neuropsychiatric disorders such as psychosis are increasingly acknowledged to be disorders of brain connectivity. Yet tools to map, model, predict, and change connectivity are difficult to develop, largely because of the complex, dynamic, and multivariate nature of interactions between brain regions. Network neuroscience (NN) provides a theoretical framework and mathematical toolset to address these difficulties. Building on areas of mathematics such as graph theory, NN in its simplest form summarizes neuroimaging data by treating brain regions as nodes in a graph and by treating interactions or connections between nodes as edges in the graph. Network metrics can then be used to quantitatively describe the architecture of the graph, which in turn reflects the network's function. We review evidence supporting the utility of NN in understanding psychiatric disorders, with a focus on normative brain network development and abnormalities associated with psychosis. We also emphasize relevant methodological challenges, such as motion artifact correction, which are particularly important to consider when applying network tools to developmental neuroimaging data. We close with a discussion of several emerging frontiers of NN in psychiatry, including generative network modeling and network control theory. We aim to offer an accessible introduction to this emerging field and motivate further work that uses NN to better understand the normative development of brain networks and alterations in that development that accompany or foreshadow psychiatric disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging - Volume 3, Issue 9, September 2018, Pages 742-753
Journal: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging - Volume 3, Issue 9, September 2018, Pages 742-753
نویسندگان
Danielle S. Bassett, Cedric Huchuan Xia, Theodore D. Satterthwaite,