کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8963254 | 1646610 | 2018 | 91 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Role of Physical Activity and Fitness in the Characterization and Prognosis of the Metabolically Healthy Obesity Phenotype: A Systematic Review and Meta-analysis
ترجمه فارسی عنوان
نقش فعالیت جسمانی و تناسب اندام در تشخیص و پیش آگهی فنوتیپ چاقی سالم متابولیک: یک بررسی منظم و متاآنالیز
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کلمات کلیدی
MHOMVPANHSPRISMASMDCRFNOST2DMHTNACLSMUOProsperoMSTMHNWmetabolically healthy normal weightCardiorespiratory fitness - آمادگی قلبیPreferred Reporting Items for Systematic reviews and Meta-analysis - آیتم های گزارش مورد نظر برای بررسی های متداول و متا آنالیزcardiovascular disease - بیماری قلب و عروقیstandardized mean difference - تفاوت میانگین استاندارد شدهInternational Prospective Register of Systematic Reviews - ثبت اختراع بین المللی بررسی های سیستماتیکRelative risk - خطر نسبیWaist circumference - دور کمرType 2 diabetes mellitus - دیابت نوع دوCVD - رسوب دهی شیمیایی بخار sedentary behaviors - رفتارهای ناتوانMetabolic syndrome - سندرم متابولیکbody mass index - شاخص توده بدنBMI - شاخص توده بدنیThe Health Improvement Network - شبکه بهبود سلامتMedical Subject Heading - عنوان موضوع پزشکیconfidence intervals - فاصله اطمینانHypertension - فشار خون بالاModerate-to-vigorous physical activity - فعالیت بدنی متوسط تا شدیدPhysical activity - فعالیت فیزیکیMuscular strength - قدرت عضلانیTHIN - لاغرMETS - متسObesity - مرض چاقیAerobics Center Longitudinal Study - مرکز ایروبیک مرکز مطالعات طولیMortality - مرگ ومیرMesh - مشhazard ratio - نسبت خطرodds ratio - نسبت شانس هاNewcastle Ottawa Scale - نیوکاسل مقیاس اتاواexercise - ورزشMetabolically healthy obesity - چاقی سالم متابولیکmetabolically unhealthy obesity - چاقی متابولیسم ناسالم
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
The aims of the present article are to systematically review and meta-analyze the existing evidence on: 1) differences in physical activity (PA), sedentary behavior (SB), cardiorespiratory fitness (CRF) and muscular strength (MST) between metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO); and 2) the prognosis of all-cause mortality and cardiovascular disease (CVD) mortality/morbidity in MHO individuals, compared with the best scenario possible, i.e., metabolically healthy normal-weight (MHNW), after adjusting for PA, SB, CRF or MST. Our systematic review identified 67 cross-sectional studies to address aim 1, and 11 longitudinal studies to address aim 2. The major findings and conclusions from the current meta-analysis are: 1) MHO individuals are more active, spend less time in SB, and have a higher level of CRF (yet no differences in MST) than MUO individuals, suggesting that their healthier metabolic profile could be at least partially due to these healthier lifestyle factors and attributes. 2) The meta-analysis of cohort studies which accounted for PA (Nâ¯=â¯10 unique cohorts, 100% scored as high-quality) support the notion that MHO individuals have a 24-33% higher risk of all-cause mortality and CVD mortality/morbidity compared to MHNW individuals. This risk was borderline significant/non-significant, independent of the length of the follow-up and lower than that reported in previous meta-analyses in this topic including all type of studies, which could be indicating a modest reduction in the risk estimates as a consequence of accounting for PA. 3) Only one study has examined the role of CRF in the prognosis of MHO individuals. This study suggests that the differences in the risk of all-cause mortality and CVD mortality/morbidity between MHO and MHNW are largely explained by differences in CRF between these two phenotypes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Cardiovascular Diseases - Volume 61, Issue 2, JulyâAugust 2018, Pages 190-205
Journal: Progress in Cardiovascular Diseases - Volume 61, Issue 2, JulyâAugust 2018, Pages 190-205
نویسندگان
Francisco B. Ortega, Cristina Cadenas-Sanchez, Jairo H. Migueles, Idoia Labayen, Jonatan R. Ruiz, Xuemei Sui, Steven N. Blair, Vicente MartÃnez-Vizcaino, Carl J. Lavie,