کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8989493 1555477 2005 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
New insights into the genetic diversity of European porcine reproductive and respiratory syndrome virus (PRRSV)
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
New insights into the genetic diversity of European porcine reproductive and respiratory syndrome virus (PRRSV)
چکیده انگلیسی
Phylogenetic analysis and pairwise comparison of the nucleotide sequences revealed that the genetic distances between the strains has greatly increased over time. The data do not support an evolutionary influence of the geographical location or the time of sample collection, nor of PRRSV vaccination on strain development. In contrast to other authors who tended to concentrate on the samples from either a common geographic origin or a short sampling period, we could not confirm geographically separate PRRSV clusters nor did we find evidence of positive selective pressure as measured by the ratio of synonymous to non-synonymous substitutions in ORF5, 6 or 7. Immunological implications and vaccination strategies are discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 107, Issues 1–2, 25 April 2005, Pages 31-48
نویسندگان
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