کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
907555 1472924 2008 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analgesic and antinociceptive effects of peripheral nerve neurostimulation in an advanced human experimental model
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
Analgesic and antinociceptive effects of peripheral nerve neurostimulation in an advanced human experimental model
چکیده انگلیسی
PNS induced strong reduction of mechanical perception due to peripheral collision of orthodromic (test stimulus) and antidromic (PNS) selective Aβ fiber excitation. Delay of N2 component and reduction of laser pain were specific to ipsilateral PNS. Divergent and common effects of ipsilateral and contralateral PNS suggest a combination of peripheral and central antinociceptive mechanisms. The study in man documents inhibition of nociception and pain by PNS and provides with an experimental model for future objectives in neuromodulation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Pain - Volume 12, Issue 4, May 2008, Pages 480-490
نویسندگان
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