Granulomes à corps étrangers exogènes et endogènes

A foreign body granuloma is a chronic lesion predominantly made of cells which belong to the monocyte-macrophage lineage. The phagocytic function is usually well developed. Such a reaction can be induced by various xenobiotic macrostructures and cristalline or amorphous exogenous micro particles, as well as by some structures of endogenous origin. The distinction between a genuine xenic reaction and a granuloma with immunogenic contribution is not easy to define in some clinical settings.