Traitement du trouble d'anxiété généralisée chez des individus présentant un trouble bipolaire : un protocole à cas unique

For three of the four participants, CBT was associated with changes in relation to the symptoms of GAD and a slight decrease in self-reported depressive symptoms. These encouraging preliminary results are congruent with those of a recent literature review (Provencher et al., 2011 [18]) identifying the impact of psychosocial interventions in the treatment of comorbid anxiety in bipolar disorder. Compared with studies on the treatment of GAD as the main disorder, the reduction in anxiety symptoms seems more modest in the current study (Ladouceur et al., 2000 [33]). It is possible that normal treatment is not as effective in patients who are more seriously affected (presence of BD/comorbidity) (Durham et al., 2003 [34]). As this study is an exploratory clinical case series, the results should be considered as preliminary. Due to the limited number of participants, it is difficult to generalize the results to all patients with bipolar disorder. In addition, the daily data is difficult to analyze because of missing data for three participants. These results are more modest than in studies of treatment of GAD, which suggests that treatment should be adapted to respond to the needs of more seriously affected patients.