کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
946120 926184 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tourette Syndrome: Gene Expression as a Tool to Discover Drug Targets
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Tourette Syndrome: Gene Expression as a Tool to Discover Drug Targets
چکیده انگلیسی
Gene expression microarrays are a high-throughput, cost-effective method for measuring the expression of all genes in a sample. By comparing the expression patterns of healthy controls to diseased subjects, the genetic regulatory pathways underlying and affected by the disease can be elucidated. Furthermore, dysregulated genes are possible candidates for pharmaceutical therapy. Here, we consider the possibility of applying this approach to Tourette syndrome. We also review current theories of Tourette syndrome etiology and pharmacology.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurotherapeutics - Volume 7, Issue 3, July 2010, Pages 302-306
نویسندگان
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