کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9616801 48895 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Esterification of streptol - a cyclitol derivative - by Candida rugosa lipase: influence of the acyl donor on regioselectivity
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی کاتالیزور
پیش نمایش صفحه اول مقاله
Esterification of streptol - a cyclitol derivative - by Candida rugosa lipase: influence of the acyl donor on regioselectivity
چکیده انگلیسی
The influence of the nature of acyl donors on the regioselectivity of Candida rugosa lipase for the esterification of streptol - a cyclitol derivative - was investigated. Excellent regioselectivity for the formation of 3,7-disubstituted derivatives was observed for vinyl butyrate (100% 3,7-derivative, 68% yield) and vinyl propionate (100% 3,7-derivative, 46% yield) as acyl donors. In contrast, for vinyl methacrylate as acyl donor, a mixture of 71% 3,7-derivative and 29% 1,7-derivative was obtained. Varying the chain length, a certain dependency of regioselectivity on the acyl donor was observed, however, no logical correlation satisfying all cases was found. Mono-substituted streptol derivatives were obtained by employing Novozym 243.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Catalysis B: Enzymatic - Volume 32, Issues 5–6, 1 March 2005, Pages 247-252
نویسندگان
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