دانلود مقالات ISI درباره 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine + ترجمه فارسی

ژنتیک تریم ضروری: از فنوتیپ به ژن، بینش از هر دو مطالعات انسان و موش

Genetics of essential tremor: From phenotype to genes, insights from both human and mouse studies

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Essential tremor; Brain; Genetics; Human population; Mouse models; Pathophysiology; ABA; Allen brain atlas; AβPPswe/PS1ΔE9; amyloid-β protein precursor and presenilin-1; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATP; adenosine tri-ph

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

ژن درمان آنتی اکسیدان در برابر مرگ سلول های عصبی

Antioxidant gene therapy against neuronal cell death

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Antioxidant gene therapy; Brain ischemia; Neurodegenerative disorders; Oxidative stress; Virus-mediated gene delivery; ROS; ΔΨm; mitochondrial membrane potential; 3-NP; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopamine; AADC; aromatic-l-amino decarboxyla

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2014 سفارش ترجمه

دیدگاه های کلیدی برای مکانیسم های دوپامین

Circadian insights into dopamine mechanisms

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ADHD; attention-deficit/hyperactivity disorder; BNST; bed nucleus of the stria terminalis; cAMP; cyclic adenosine monophosphate; DA; dopamine; DAT; dopamine transporter; DOPAC; 3,4-dihydroxyphenylacetic acid; FEO; Food-Entrainable circadian Oscillator; LH

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2014 سفارش ترجمه

سهم دیفرانسیل از ایزوکسین های لیپوکسیژناز به آسیب پذیری ناهمگونی

Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AA; arachidonic acid; AD; Alzheimer's disease; ANOVA; analysis of variance; DA; dopamine; DAB; 3,3′-diaminobenzidine; DOPAC; dihydroxyphenylacetic acid; EDTA; ethylenediaminetetraacetic acid; GFAP; glial acidic fibrillary protein; HETE; hydroxyeicosat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

معنای حرکتی میتوکندری به زندگی عصبی

The meaning of mitochondrial movement to a neuron's life

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Akt-GSK3β; Akt-Glycogen Synthase Kinase 3β; ALS; Amyotrophic Lateral Sclerosis; CCCP; Carbonyl cyanide m-chlorophenyl hydrazine; CMT; Charcot-Marie-Tooth; DA; Dopamine; DISC1; Disrupted In Schizophrenia 1; FEZ1; Fasciculation and Elongation Protein-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

بیماری پارکینسون: از آسیب شناسی به مکانیزم های بیماری مولکولی

Parkinson disease: from pathology to molecular disease mechanisms

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; SNc; substantia nigra pars compacta; PD; Parkinson disease; NMS; nonmotor symptoms; MAO-B; monoamine oxidase-B; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-OHDA; 6-hydroxy dopamine; GBA; glucocerebrosidase; STN

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

متابولیسم گلوتاتیون و بیماری پارکینسون

Glutathione metabolism and Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ABC; ATP-binding cassette transporter; ASK1; apoptosis signal-regulating kinase 1; BBB; blood-brain barrier; BSO; l-buthionine-(S,R)-sulfoximine; COMT; catechol-O-methyltransferase; DA; dopamine; DAT; dopamine transporter; DHBT-1; 7-(2-aminoethyl)-3,4-d

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

ژنتیک و آهن در سیستم زیست شناسی بیماری پارکینسون و برخی از اختلالات مرتبط با آن

Genetics and iron in the systems biology of Parkinson's disease and some related disorders

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; LB; Lewy body; PD; Parkinson's disease; SN; substantia nigra; ROS; reactive oxygen species; IRE/IRP; iron responsive element/iron responsive protein; NBIA; neurodegeneration with brain iron accumulation; KRS; Kufor-Rakeb syndrome; LRRK2; leucine rich re

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

ترکیبات ضد التهابی به طور طبیعی مشتق شده از گیاهان دارویی چینی

Naturally derived anti-inflammatory compounds from Chinese medicinal plants

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Aβ; β-amyloid protein; AD; Alzheimer's disease; AP-1; Activator protein-1; AS; Atherosclerosis; CCl4; Carbon tetrachloride; CFA; Complete Freund's Adjuvant; CIA; Type II collagen-induced arthritis; CMM; Chinese Material Medica; Con A; Concanavalin A; CO

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2013 سفارش ترجمه

Resveratrol prolongs lifespan and improves 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced oxidative damage and behavioural deficits in Drosophila melanogaster

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine; Resveratrol; Parkinson's disease; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Decreased Mcl-1 protein level in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Myeloid cell leukemia 1; Apoptosis; Neurodegeneration; Striatum; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Silymarin prevents apoptosis through inhibiting the Bax/caspase-3 expression and suppresses toll like receptor-4 pathway in the SNc of 6-OHDA intoxicated rats

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Bax; Bcl-2-associated X protein; Bcl2; B-cell lymphoma 2; Caspase; cysteine-aspartic proteases; CNS; central nervous system; DA; dopaminergic; ECL; enhanced chemiluminescence; EDTA; ethylenediaminetetraacetic acid; ELISA; enzyme-linked immunosorbent ass

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A comparative study about EPA-PL and EPA-EE on ameliorating behavioral deficits in MPTP-induced mice with Parkinson's disease by suppressing oxidative stress and apoptosis

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; EPA; eicosapentaenoic acid; PD; Parkinson's disease; ω-3 LCPUFA; Omega-3 long chain polyunsaturated fatty acids; EPA-PL; eicosapentaenoic acid enriched phospholipids; EPA-EE; eicosapentaenoic acid-ethyl ester; DHA; docosahexaenoic acid; MPTP; 1-methyl-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Prion-like propagation of α-synuclein in the gut-brain axis

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; CNS; central nervous system; DA; dopamine; DMV; dorsal motor nucleus of the vagus; ENS; enteric nervous system; GI; gastrointestinal; IL-1; interleukin-1; LBs; Lewy bodies; LPS; lipopolysaccharide; LAG3; lymphocyte-activation gene 3; MPTP; 1-Methyl-4-phen

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effect of the carnosine - α-lipoic acid nanomicellar complex in a model of early-stage Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Parkinson's disease; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Rat; Neuroprotection; Carnosine; α-lipoic acid; Nanomicellar complex of carnosine and α-lipoic acid; Lipid peroxidation; Catecholamines; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPT

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Trx-1 ameliorates learning and memory deficits in MPTP-induced Parkinson's disease model in mice

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson's disease; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; SNpc; substantia nigra pars compacta; MWM; Morris water maze; Trx-1; Thioredoxin-1; TH; Tyrosine hydroxylase; D1R; D1 receptor; ITL; Initial transfer latency; NR2B; N-methyl-D-as

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Endurance Exercise Mediates Neuroprotection Against MPTP-mediated Parkinson's Disease via Enhanced Neurogenesis, Antioxidant Capacity, and Autophagy

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; BrdU; 5-Bromo-2′-Deoxyuridine; CuZnSOD; copper zinc superoxide dismutase; DAT; dopamine transporter; DG; dentate gyrus; EE; endurance exercise; GPX; glutathione peroxidase; HO-1; heme oxygenase I; MnSOD; manganese superoxide dismutase; MPTP; 1-methyl-4-

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Long Noncoding RNA SNHG1 Promotes Neuroinflammation in Parkinson's Disease via Regulating miR-7/NLRP3 Pathway

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; lncRNAs; long noncoding RNAs; LPS; lipopolysaccharide; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NLRP3; nod-like receptor protein 3; PD; Parkinson's disease; SNHG1; small nucleolar RNA host gene 1; SNpc; substantia nigra pars compacta; TNF; tu

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

miR-494-3p modulates the progression of in vitro and in vivo Parkinson's disease models by targeting SIRT3

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson's disease; SOD; superoxide dismutase; LDH; lactate dehydrogenase; TNF-α; tumor necrosis factor-α; IL-1β; interleukin-1β; ROS; reactive oxygen species; SNpc; substantia nigra pars compacta; DA; dopaminergic; miRNAs; microRNAs; snRNA; sm

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effect of a standardized extract of Centella asiatica ECa233 in rotenone-induced parkinsonism rats

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ECa233; Centella asiatica; Mitochondria; Rotenone; Parkinson's disease; ATP; adenosine-5′- triphosphate; CMC; carboxymethylcellulose; DMSO; dimethyl sulfoxide; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HRP; horseradish peroxidase; MDA; malondiald

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Phosphorylated α-Synuclein Accumulations and Lewy Body-like Pathology Distributed in Parkinson's Disease-Related Brain Areas of Aged Rhesus Monkeys Treated with MPTP

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; CN III; oculomotor nucleus; I.M.; intramuscular injection; LBs; Lewy bodies; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NHP; non-human primate; OC; occipital cortex; PD; Parkinson's disease; PFC; prefrontal cortex; P-Ser 129 α-syn; phosphoryla

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; K-ATP; ATP-sensitive potassium; PD; Parkinson's disease; DA; dopaminergic; Kir; inwardly rectifying potassium channel; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; SNc; substantia nigra compacta; Gli; glibenclamide; DMT1; divalent metal transporter

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

mGlu4 allosteric modulation for treating Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Parkinson's disease; Dyskinesia; Glutamate; Dopamine; mGlu4; 6-OHDA; 6-hydroxydopamine; ADX88178; 4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-yl]pyrimidin-2-amine; AIM; abnormal involuntary movements; CODA-RET; complemented donor acceptor reson

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Paraquat and MPTP induce alteration in the expression profile of long noncoding RNAs in the substantia nigra of mice: Role of the transcription factor Nrf2

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Anti-DIG; antibody against digoxigenin; APES; 3-aminopropyl-triethoxysilane; ARE; antioxidant response element; BSA; bovine serum albumin; CNC; coding-non-coding; Cy3; cyanine dye 3; DA; dopamine; DAPI; 4,6-diamidino-2-phenylindole; DEPC; Diethyl pyrocarb

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Ginsenoside Rb1 confers neuroprotection via promotion of glutamate transporters in a mouse model of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Parkinson's disease; Ginsenoside Rb1; Glutamatergic transmission; Glutamate transporters; EAAC1; excitatory amino acid carrier-1; EAATs; excitatory amino acid transporters; GLAST; glutamate/aspartate transporter; GLT-1; glutamate transporter-1; mEPSCs; mi

دانلود رایگان متن کامل مقاله ISI 66 صفحه سال انتشار : 2018 سفارش ترجمه

Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 5-HT; 5-hydroxytryptamine; Aβ; β-amyloid; ABCA8; ATP binding cassette subfamily A member 8; AD; Alzheimer's disease; ADP; adenosine diphosphate; AGD; argyrophilic grain disease; ALS; amyotrophic lateral sclerosis; AMBRA-1; autophagy and beclin 1 regul

دانلود رایگان متن کامل مقاله ISI 131 صفحه سال انتشار : 2018 سفارش ترجمه

Mitochondrial ROS-mediated post-transcriptional regulation of α-synuclein through miR-7 and miR-153

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; α-SYN; alpha-synuclein; ROS; reactive oxygen species; 3′-UTR; 3′-untranslated region; DAT; dopamine transporter; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; α-synuclein; microRNA; 3′-UTR; Mitochondria; Pa

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

A preclinical study on the combined effects of repeated eltoprazine and preladenant treatment for alleviating L-DOPA-induced dyskinesia in Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 5-HT; Serotoninergic; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NHP; Non-human primate; PD; Parkinson's disease; LID; L-DOPA-induced dyskinesia; L-DOPA; L-3,4-dihydroxyphenylalanine; Parkinson's disease; L-DOPA-induced dyskinesia; 5-HT; Adenosin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Icariin; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Phosphatidylinositol 3-kinase; Mitogen-activated protein kinase kinase; Dopamine; Parkinson's disease; DA; dopamine; IGF-1R; insulin-like growth factor-1 receptor; IRS-1; insulin receptor substrate-1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Protective function of SLC30A10 induced via PERK-ATF4 pathway against 1-methyl-4-phenylpyridinium

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; SLC30A10; Parkinson's disease; Endoplasmic reticulum stress; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpiridium ion; ATF4;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Neuroprotective effects of total flavonoid fraction of the Epimedium koreanum Nakai extract on dopaminergic neurons: In vivo and in vitro

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DA; dopamine; ERE; estrogen response element; MES23.5; dopaminergic hybridoma cell line; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SN; substantial nigra; SNpc; substantia nigra pars

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of Zishenpingchan granule prepared from Chinese medicinal substances on the c-Jun N-terminal protein kinase pathway in mice with Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; MAP kinase signaling system; Inflammation; Apoptosis; Parkinson disease; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; BDNF; brain derived neurotrophic factor; GDNF; glia derived neurotrophic factor; GFAP; glial fibrillary protein; Iba-1; ionized calcium binding adaptor molecule 1; IL-1β; interleukin-1β; LPS; lipopolysaccharide; LME; l-leucine-methyl esther; MAPK; mitog

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Subcellular expression of aquaporin-4 in substantia nigra of normal and MPTP-treated mice

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AQP4; aquaporin-4; DA; dopaminergic; GFAP; glial fibrillary acidic protein; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SN; substantia nigra; SNpc; substantia nigra pars compacta; TH; tyrosine hydroxylase; aquaporin-4; a

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperNrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; GPx; glutathione peroxidase; HO-1; heme oxygenase-1; MPP+;  1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Nrf2; nuclear factor erythroid 2 related factor 2; PD; Parkinson's disease; SNpc; substantia nigra pars compacta;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DA; dopamine; DOPAC; dihydroxyphenylacetic acid; HVA; homovanilic acid; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SN; substantia nigra; SNc; substantia nigra pars compacta; SNr; s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Metformin lowers α-synuclein phosphorylation and upregulates neurotrophic factor in the MPTP mouse model of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Parkinson's disease; Metformin; MPTP; PP2A; BDNF; PD; Parkinson's disease; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; AMPK; 5′-adenosine mono-phosphate-activated protein kinase; PP2A; protein phosphatase 2A; TH; tyrosine hydroxylase; BDNF; brai

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Short- and long-term effects induced by repeated 6-OHDA intraventricular administration: A new progressive and bilateral rodent model of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; ICV; intracerebroventricular; MFB; medial forebrain bundle; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PBS; phosphate buffer saline; PD; Parkinson's disease; SNpc; substantia nigra pars compacta; VTA; ventral tegmenta

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AADC; aromatic l-amino acid decarboxylase; DA; dopamine; DAT; dopamine membrane transporter; DBH; dopamine beta-hydroxylase; FR; Fluoro-Ruby; HPLC-ED; high performance liquid chromatography with electrochemical detection; l-DOPA; l-3,4-dihydroxyphenylalan

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 3α-diol; 5α-androstane-3α, 17β-diol; 3β-diol; 5α-androstane-3β, 17β-diol; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; DA; dopamine; DAT; dopamine transporter; DHEA; dehydroepiandrosterone; DHP; 5α-dihydroprogesterone; DHT; dihydrotestost

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Mulberry fruit ameliorates Parkinson's-disease-related pathology by reducing α-synuclein and ubiquitin levels in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Mulberry fruit; α-Synuclein; Parkinson's disease; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Probenecid;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Treadmill exercise produces neuroprotective effects in a murine model of Parkinson's disease by regulating the TLR2/MyD88/NF-κB signaling pathway

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ANOVA; analysis of variance; DAT; dopamine transporter; HPLC; High Performance Liquid Chromatography; IL-1β; interleukin-1β; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MyD88; myeloid differentiation factor-88; NADPH; nicotinamide adenine dinucl

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Chronic cerebral hypoperfusion independently exacerbates cognitive impairment within the pathopoiesis of Parkinson's disease via microvascular pathologys

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson's disease; CHH; chronic cerebral hypoperfusion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; BCCAs; bilateral common carotid arteries stenosis; PDCN; Parkinson's disease with normal cognitive performance; PD-MCI; Parkinson's disease w

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Neuroprotective and Neuro-restorative Effects of Minocycline and Rasagiline in a Zebrafish 6-Hydroxydopamine Model of Parkinson's Disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; MAO; monoamine oxidase; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; zebrafish; Parkinsons's disease; 6-OHDA; locomotor activity; immunohistochemistry; neuro-restoration;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Pathological α-synuclein exacerbates the progression of Parkinson's disease through microglial activation

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AKT; protein kinase B; AP-1; activator protein-1; BV-2; immortalized murine microglia cell line; CD11b; cluster of differentiation 11b; CD36; cluster of differentiation 36; CD44; cluster of differentiation 44; CD68; cluster of differentiation 68; CNS; cen

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DA neuron; dopaminergic neuron; DHE; dihydroethidium; DSP-4; N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride; Iba-1; ionized calcium binding adaptor molecule-1; iNOS; inducible nitric oxide synthase; LC/NE neuron; noradrenergic locus coeruleus

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Expanding the repertoire of L-DOPA's actions: A comprehensive review of its functional neurochemistry

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AADC; aromatic L amino acid decarboxylase; COMT; catechol-O-methyl-transferase; CSF; cerebrospinal fluid; 6-OHDA; 6-hydroxydopamine; DBH; dopamine β-hydroxylase; DOPAC; 3,4-dihydroxyphenylacetic acid; 3-MT; 3-methoxytyramine; DA; dopamine; DAT; dopamine

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Involvement of PKCα and ERK1/2 signaling pathways in EGCG's protection against stress-induced neural injuries in Wistar rats

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 5-HT; 5-hydroxytryptamine or serotonin; AD; Alzheimer's disease; ATP; adenosine triphosphate; BBB; blood-brain barrier; CNS; central nervous system; DA; dopamine; EGCG; epigallocatechin-3-gallate; ERK1/2; extracellular signal-regulated kinase 1/2; GC; g

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Opening of ATP-sensitive K+ (KATP) channels enhance hydroxyl radical generation induced by MPP+ in rat striatum

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DA; dopamine; OH; hydroxyl radical; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+;  1-methyl-4-phenylpyridinium ion; DHBA; dihydroxybenzoic acid; MAO; monoamine oxidase; Cromakalim; Nicorandil; ATP-sensitive K+ (KATP) channel; 1-Methyl-4-pheny

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Targeted methylation sequencing reveals dysregulated Wnt signaling in Parkinson disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Epigenetic regulation; Neurodegenerative diseases; Environmental toxins; Neurogenesis; PD; Parkinson disease; DA; dopaminergic; CGIs; CpG islands; T-DMRs; tissue differential methylation regions; TSS; transcription start sites; MPP+; 1-methyl-4-phenylpyri

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه