دانلود مقالات ISI درباره 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine + ترجمه فارسی

Alteration of nuclear factor-kappaB pathway promote neuroinflammation depending on the functions of estrogen receptors in substantia nigra after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson's disease; SN; substantia nigra; Iba1; ionized calcium binding adaptor molecule 1; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; TNF-α; tumor necrosis factor-alpha; b.w.; body weight; GFAP; glial fib

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The role of TWEAK/Fn14 signaling in the MPTP-model of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; COX-2; cycoloxygenase-2; DOPAC; 3,4-dihydrophenylacetic acid; FN14; fibroblast growth factor-inducible 14; HPLC; high-performance liquid chromatography; HRP; horseradish peroxidase; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NF-κB; nuclear facto

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Characterizations of a synthetic pituitary adenylate cyclase-activating polypeptide analog displaying potent neuroprotective activity and reduced in vivo cardiovascular side effects in a Parkinson's disease model

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Neurodegeneration; Neurodegenerative disorders; PACAP; Dopaminergic neuron survival; SH-SY5Y neuroblastoma cell survival; Vasodilation; Cq; quantification cycle; Eu3; europium(III) cryptate; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

An evaluation of istradefylline treatment on Parkinsonian motor and cognitive deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque models

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Istradefylline; KW-6002; Parkinson's disease; l-DOPA-induced dyskinesia; Cognition; MPTP; CLD; Chronic low dose; CPT; Continuous performance task; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NHP; Non-human primate; PD; Parkinson's disease; LID;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Ginsenoside Rg1 attenuates motor impairment and neuroinflammation in the MPTP-probenecid-induced parkinsonism mouse model by targeting α-synuclein abnormalities in the substantia nigra

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Parkinson'; s disease; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Neuroinflammation; α-Synuclein; Ginsenoside Rg1;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

N-methyltetrahydropyridines and pyridinium cations as toxins and comparison with naturally-occurring alkaloids

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP); 1-methyl-4-phenylpyridinium cation (MPP+); Paraquat; β-carboline; Tetrahydroisoquinoline; Neurotoxins; Neuroprotectants; Parkinson's disease; BBB; blood-brain barrier; βCs; β-carbolines; βC+s; β-ca

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Histone H3 acetylation in the postmortem Parkinson's disease primary motor cortex

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; AcH3; acetylated histone H3; AcH3K9; acetylated histone H3 lysine 9; AcH3K14; acetylated histone H3 lysine 14; AcH3K18; acetylated histone H3 lysine 18; AcH3K23; acetylated his

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

In vitro 6-hydroxydopamine-induced toxicity in striatal, cerebrocortical and hippocampal slices is attenuated by atorvastatin and MK-801

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-Hydroxydopamine; ATOR; atorvastatin; DCF; dichlorofluorescein; DCFH; 2´,7´-dichlorofluorescein; DMSO; dimethyl sulfoxide; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; H2DCFDA; 2,7-dichlorofluorescein diacetate; HMG-CoA; 3-hydro

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of the pituitary adenylate cyclase-activating polypeptide on the autophagic activation observed in in vitro and in vivo models of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Akt; protein kinase B; Bcl-2; B-cell lymphoma 2 anti-apoptotic protein; DA; dopaminergic; DAPI; 2-(4-amidinophenyl)-1 H-indole-6-carboxamidine hydrochloride; FBS; fetal bovine serum; GFP; green fluorescent protein; JNK; c-Jun. N-terminal kinase; LC3 I an

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Abdil solution; antibody dilution solution; A.U.; arbitrary units; BBB; blood brain barrier; BSA; bovine serum albumin; DCPIP; 2,6-dichlorophenolindophenol; DD; deacetylase domain; dpf; days post fertilization; DMB; dynein motor binding; HAD; HDAC associa

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

The afferent signaling complex: Regulation of type I spiral ganglion neuron responses in the auditory periphery

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Cochlea; Inner hair cells; Type I spiral ganglion neurons; Lateral olivocochlear efferents; Ion channels and transporters; Neurotransmitter receptors; Postsynaptic density; Auditory neuropathy and synaptopathy; ABR; auditory brainstem response; ACh; acety

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

A newly discovered neurotoxin ADTIQ associated with hyperglycemia and Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 1-Acetyl-6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline (ADTIQ); Diabetes; Parkinson's disease (PD); Methylglyoxal; ADTIQ; 1-acetyl-6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Salsolinol; 1-methyl-4-ph

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Increased neurotrophic factor levels in ventral mesencephalic cultures do not explain the protective effect of osteopontin and the synthetic 15-mer RGD domain against MPP + toxicity

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; BDNF; brain-derived neurotrophic factor; ED-1; ectodermal dysplasia 1; GDNF; glial-derived neurotrophic factor; GFAP; glial fibrillary acidic protein; MPP +; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahyd

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Voxel-based morphometry of the marmoset brain: In vivo detection of volume loss in the substantia nigra of the MPTP-treated Parkinson's disease model

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Cd; caudate nucleus; DA; dopaminergic; GM; gray matter; LC; locus coeruleus; LH; lateral hypothalamus; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MRI; magnetic resonance imaging; PBS; phosphate-buffered saline; PD; Parkinson's disease; Pu; puta

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The effect of neuronal conditional knock-out of peroxisome proliferator-activated receptors in the MPTP mouse model of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; ANOVA; analysis of variance; DOPAC; 3,4-dihydrophenylacetic acid; HPLC; high-performance liquid chromatography; IL; interleukin; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; MPP; 1-methyl-4-phenylpyridinium; M

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Translational research for Parkinson׳s disease: The value of pre-clinical primate models

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson׳s disease; SNpc; substantia nigra pars compacta; L-DOPA; Levodopa, 3,4-dihydroxyphenylalanine; 6OHDA; 6-hydroxydopamine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; AADC; L-aromatic amino acid decarboxylase; TH; tyrosine hydroxylase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-apoptotic effect of modified Chunsimyeolda-tang, a traditional Korean herbal formula, on MPTP-induced neuronal cell death in a Parkinson's disease mouse model

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ABC; avidin-biotin peroxidase complex; DG; modified Chungsimyeolda-tang; FBS; fetal bovine serum; MYH; modified Youldahanso-tang; PD; Parkinson's disease; MEM; minimal essential medium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+; 1-methyl-4-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7: A miRNA with expanding roles in development and disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ACK1; activated CDC42 kinase 1; BASP1; brain abundant, membrane attached signal protein 1; c-Myc; v-Myc avian myelocytomatosis viral oncogene homolog; CD57; cluster of differentiation 57; CD44; cluster of differentiation 44; ciRS-7; circular RNA sponge fo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DAT; dopamine transporter; PD; Parkinson's disease; DAT-tg; dopamine transporter over-expressing transgenic; DAT-KO; dopamine transporter knock-out; VMAT2; vesicular monoamine transporter 2; VMAT2-kd; vesicular monoamine transporter 2 knock-down; MPTP; 1-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular chaperones and neuronal proteostasis

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 17-AAG; 17-allylamino-17-demethoxygeldanamycin; 17-DMAG; 17-dimethylamino-ethylamino-17-demethoxygeldanamycin; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ARSACS; autosomal recessive spastic ataxia of Charlevoix-Saguena

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Increased brain bio-distribution and chemical stability and decreased immunogenicity of an engineered variant of GDNF

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-Hydroxy-dopamine; BBB; Blood-brain-barrier; CEX; Cation Exchange chromatography; CHO; Chinese Hamster Ovary; DOPAC; Dihydroxyphenylacetic acid; Dopa; 3,4-dihydroxyphenylalanine; DA; Dopamine; ECM; Extracellular matrix; GDNF; Glial cell line-de

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxy-dopamine; Akt, PKB; protein kinase B, serine/threonine-specific protein kinase; BDNF; brain derived neurotrophic factor; CaMKIIβ; calcium-calmodulin-dependent protein kinase II β isoform; cAMP; 3′,5′-cyclic adenosine monophosphate;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Enteric nervous system; Central nervous system; Inflammation; Macrophage; Microglia; Tyrosine hydroxylase; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

HIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DA; dopaminergic; EF-5; 2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide; egln1; egl nine homologue1; GFAP; Glial Fibrillary Acidic Acid; HIF; Hypoxia Inducible Factor; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PBS; phosphat

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Current knowledge and pharmacological profile of berberine: An update

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 5-HT; 5-hydroxytryptamine; 6-OHDA; 6-hydroxydopamine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; BBB; blood brain barrier; BChE; butyrylcholinestesrase; CD; cluster of differentiation; Cdk; cyclin-dependent ki

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

The protein l-isoaspartyl (d-aspartyl) methyltransferase protects against dopamine-induced apoptosis in neuroblastoma SH-SY5Y cells

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; AdoMet; S-adenosyl-l-methionine; CaPIMT1; chick pea PIMT; DA; dopamine; DMSO; dimethyl sulfoxide; gly-LDL; glycated Low-Density Lipoprotein; H2DCFDA; 2′,7′-dichlorodihydrofluorescein diacetate; MAO; monoamine oxidase; MPTP;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of l-tryptophan on l-DOPA-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 5-HT; 5-Hydroxytryptamine; 5-HTP; 5-Hydroxytryptophan; BBB; Blood-brain barrier; DA; Dopamine; l-DOPA; l-3,4-Dihydroxyphenylalanine; l-AADC; l-Amino acid decarboxylase; LID; l-DOPA-induced dyskinesia; MPTP; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Research reportAnti-Parkinson effects of a selective alpha2C-adrenoceptor antagonist in the MPTP marmoset model

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ANOVA; analysis of variance; CNS; central nerve system; DA; dopamine; DA-ergic; dopaminergic; GPi; globus pallidus interna; LC; locus coeruleus; l-DOPA; l-dihydroxy-phenylalanine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NE; noradrenergic; PPN;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Antioxidant action of 7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cytotoxicity

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AD; Alzheimer's disease; ANOVA; one-way analysis of variance; ATCC; American type culture collection; DA; dopamine; 7,8-DHF; 7,8-dihydroxyflavone; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ECL; enhanced chemiluminescence; F

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Short communicationNeuroprotective effect of silymarin in a MPTP mouse model of Parkinson's disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Parkinson's disease; Neuroprotection; Silymarin; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Structure and function of the ARH family of ADP-ribosyl-acceptor hydrolases

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Gαs; α-subunit of the stimulatory guanine nucleotide-binding protein; ARH; ADP-ribosyl-acceptor hydrolase; AIF; apoptosis-inducing factor; mito-PARP1cd; catalytic domain of PARP1 with a mitochondrial t

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The Chinese herbal formula Liuwei dihuang protects dopaminergic neurons against Parkinson's toxin through enhancing antioxidative defense and preventing apoptotic death

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Liuwei dihuang; Traditional Chinese medicine; Neuroprotection; Dopaminergic neurons; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Subthalamotomy-induced changes in dopamine receptors in parkinsonian monkeys

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; DA; dopamine; DAT; dopamine transporter; DL; dorsolateral; DM; dorsomedial; DOPAC; 3,4-dihydroxyphenylacetic acid; GPe; globus pallidus pars externa; GPi; globus pallidus pars interna; HFS; high-frequency stimulation; HPLC; high

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of the Parkinsonian toxin MPP+ on electrophysiological properties of nigral dopaminergic neurons

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Dopamine; D2 autoreceptors; KATP channels; HCN channels; Brain slice; ACSF; artificial cerebrospinal fluid; ATP; adenosine triphosphate; DA; dopamine; DAT; dopamine transporter; GIRK; G protein-coupled inwardly rectifying potassium channels; HCN; hyperpol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

PPARγ activation rescues mitochondrial function from inhibition of complex I and loss of PINK1

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson's disease; PPARγ; peroxisome proliferator-activated receptor gamma; TZDs; thiazolidinediones; RGS; Rosiglitazone; ΔΨm; Mitochondrial membrane potential; ROS; reactive oxygen species; PI; propidium Iodide; TMRM; Tetramethylrhodamine methyl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Beyond the basal ganglia: cFOS expression in the cerebellum in response to acute and chronic dopaminergic alterations

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; DN; dentate nucleus; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; PN; pontine nuclei; SNc; substantia nigra pars compacta; SNr; SN reticulata; STN; subtalamic nucleus; cerebellum; dopamine; halo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Development of allosteric modulators of GPCRs for treatment of CNS disorders

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 5MPEP; 5-methyl-6-(phenylethynyl)-pyridine; 6-OHDA; 6-hydroxydopamine; 7TMR; seven transmembrane receptor; 77-LH-28-1; 1-[3-(4-butyl-1-piperidinyl)propyl]-3,4-dihydro-2(1H)-quinolinone; AC-42; 4-n-butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine; ACh

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: Focus on modulation of CNS monoamine neurotransmitter release

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Enzyme active site structure; Presynaptic inhibition; Exocytotic and non-exocytotic release; Neuroprotection; Parkinson's disease; Affective disorders; MAO; monoamine oxidase; MAO-A; monoamine oxidase isoform A; MAO-B; monoamine oxidase isoform B; COMT; c

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Preconditioning provides neuroprotection in models of CNS disease: Paradigms and clinical significance

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Preconditioning; Neuroprotection; Ischemia; Traumatic brain injury; MCAO; middle cerebral artery occlusion; 2VO; two vessel occlusion; 3-NPA; 3-Nitropropionic acid; 4VO; four vessel occlusion; BCCAO; bilateral common carotid artery occlusion; CSD; cortica

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2014 سفارش ترجمه

α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson disease; SNPc; substantia nigra pars compacta; α-syn; α-synuclein; GTPCH; GTP cyclohydrolase I; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpyridinium; NOS; nitric oxide synthase; DAT; dopamine transporter; B

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2014 سفارش ترجمه

The effect of dopamine on MPTP-induced rotarod disability

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; SN; substantia nigra pars compactor; PD; Parkinson's disease; l-Dopa; l-3,4-dihydroxyphenylalanine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; LIDS; l-Dopa induced dyskinesias; Parkinson's disease; MPTP; Dopamine; Rotarod;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The effects of fast-off-D2 receptor antagonism on L-DOPA-induced dyskinesia and psychosis in parkinsonian macaques

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; D2; dopamine receptor subtype 2; L-DOPA; L-3,4-dihydroxyphenylalanine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; CB1; cannabinoid receptor type 1; NMDA; N-methyl-d-aspartic acid; PDMA; Parkinsonism During MPTP Administra

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Neuroprotective effects of madecassoside in early stage of Parkinson's disease induced by MPTP in rats

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson's disease; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; SN; substantia nigra; DA; dopamine; MDA; malonyldialdehyde; GSH; reduced glutathione; qRT-PCR; quantitative real-time polymerase chain reaction; DOPAC; 3 4-dihydroxyphenylacetic

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Abnormal involuntary movement (AIM) expression following D2 dopamine agonist challenge is determined by the nature of prior dopamine receptor stimulation (priming) in 6-hydroxydopamine lesioned rats

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA; 6-hydroxydopamine; AIMs; abnormal involuntary movements; Apo; apomorphine; i.p.; intraperitoneal; l-Dopa; l-3,4-dihydroxyphenylalanine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's Disease; SKF; SKF38393; TH; tyrosine hydrox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ABC proteins; ATP binding cassette proteins; BBB; blood-brain barrier; Bcrp; breast cancer resistance protein; CsA; cyclosporin A; IP; intra peritoneal; IV; intra venous; Mdr1; multi drug resistance 1; MitoF; 11-fluoroundecyltriphenylphosphonium mesylat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

AIF, reactive oxygen species, and neurodegeneration: A “complex” problem

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AIF; apoptosis inducing factor; DCFH-DA; dichlorodihydrofluorescein; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NMDA; N-methyl d-aspartate; ROS; reactive oxygen species; Mitochondria; Electron transport; Complex

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Parkinson's disease; Neuroprotection; Regulatory T cells; Innate immunity; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Neuroinflammation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Lack of CCR5 modifies glial phenotypes and population of the nigral dopaminergic neurons, but not MPTP-induced dopaminergic neurodegeneration

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD; Parkinson's disease; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP +; 1-methyl-4-phenyl pyridium; MAO; monoamine oxidase; DAT; dopamine transporter; CCR; C-C chemokine receptor; MIP; macrophage inflammatory protein; KO; knockout; WT; wild

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Neuroprotective changes of thalamic degeneration-related gene expression by acupuncture in an MPTP mouse model of parkinsonism: Microarray analysis

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; MPTP; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; DA; Dopamine; 6-OHDA; 6-Hydroxydopamine; TBS; Tris-buffered saline; TH; tyrosine hydroxylase; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; PVDF; polyvinyl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Comparison of motor performance, brain biochemistry and histology of two A30P α-synuclein transgenic mouse strains

Keywords: 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; aSyn; α-synuclein; ANOVA; analysis of variance; DOPAC; 3,4-dihydroxyphenylacetic acid; DA; dopamine; HVA; homovanillic acid; 5-HT; 5-hydroxytryptamine; 6-OHDA; 6-hydroxydopamine; LB; Lewy bodies; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PFA; p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه