Keywords: Obesity; Polyphenol; Adipogenesis; PPARγ; Lipid; Rice; ABTS; 2,2â²-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid; ACO; acyl-CoA oxidase; CYP4A10; cytochrome P450; AMPK; AMP-activated protein kinase; AT; adipose tissue; C/EBPâ; CAAT/enhancer-bindin
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Keywords: Dio2; type II iodothyronine deiodinase; Dio3; type III iodothyronine deiodinase; TRα and TRβ; thyroid hormone receptor α and β; SOD; superoxide dismutase; HSP; heat shock protein; PHGPx; phospholipid hydroperoxide glutathione peroxidase; CPT; carnitin
Keywords: ACOX; acyl-CoA oxidase; DCA; dicarboxylic fatty acid; DHA; docosahexaenoic acid; DHCA; 3α,7α-dihydroxycholestanoic acid; MCK; muscle creatine kinase; MFP; multifunctional protein; PBD; peroxisome biogenesis disorder; PUFA; polyunsaturated fatty acid; RO
Keywords: AOX; acyl-CoA oxidase; CAC; citric acid cycle; DNL; de novo lipogenesis; MRS; magnetic resonance spectroscopy; FSR; fractional synthesis rate; HGP; hepatic glucose production; GSH; glutathione; GNG; gluconeogenesis; GC-MS; gas chromatography mass spectrom
Keywords: Acot; acyl-CoA thioesterase; Acox; acyl-CoA oxidase; BAT; brown adipose tissue; Cpt; carnitine palmitoyltransferase; ETC; electron transport chain; HFD and LFD; high- and low-fat diet; Ppar; peroxisome proliferator-activated receptor; SNS; sympathetic ner
Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease
Keywords: ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; ADIPO-IR; adipose tissue insulin resistance; AMKP; AMP-activated proteinkinase; AUC; the area under the curve; ChREBP; carbohydrate response element binding protein; CPT; carnitine palmitoyltransferase;
Keywords: ACA; Acetyl-CoA Acyltransferase; ACACa; acetyl-CoA carboxylase 1; ACACb; acetyl-CoA carboxylase 2; ACC; Acetyl CoA Carboxylase; ACOX; Acyl-CoA Oxidase; ACS; Acetyl-CoA synthetase; APOA-1; apolipoprotein A-I; BBzP; Butyl benzyl phthalate; BPA; Bisphenol A;
Keywords: ACOX; acyl-CoA oxidase; AO; alcohol oxidase; CCS; copper chaperone of SOD1; DTM; docking/translocation machinery; Gpd1p; glycerol-3-phosphate dehydrogenase 1; LDHA/B/Bx; lactate dehydrogenase isoforms A, B and B readthrough-extended, respectively; PIM; pe
Keywords: ABC; ATP-binding cassette; ACAA1; acetyl-CoA acyltransferase; ACOX; acyl-CoA oxidase; BAAT; bile acid CoA-amino acid N-acyl transferase; C24-bile acid; cholanoic acid; C27-bile acid; cholestanoic acid; CDCA; chenodeoxycholic acid; Cn-DCA; straight chain d
Keywords: Acox; acyl-CoA oxidase; Agpat; acylglycerol-3-phosphate-O-acyltransferase; aP2; adipose fatty acid binding protein; Atgl; adipose triglyceride lipase; AUC; area under the curve; B. wadsworthia; Bilophila wadsworthia; Cd36; cluster of differentiation 36; C
Keywords: ACO; Acyl-CoA oxidase; ATGL; Adipose triglyceride lipase; CPT1; Carnitine palmitoyltransferase 1; FAS; Fatty acid synthase; FAT/CD36; Fatty acid translocase/cluster of differentiation 36; GLUT; Glucose transporter; LPL; Lipoprotein lipase; PFK; Phosphofru
Keywords: Lysosome-associated membrane protein-2; Autophagy; Diabetes; Obesity; Lysosome; ATF4; activating transcription factor 4; ACO; acyl-CoA oxidase; BAT; brown adipose tissue; Cidea; cell death-inducing DNA fragmentation factor-α-like effector A; FGF21; fibro
Keywords: ACO; acyl-CoA oxidase; ACS; acyl-CoA synthase; AMPK; AMP-activated protein kinase; CPT; carnitine palmitoyl transferase; ERK1/2; extracellular signal-regulated protein kinase 1/2; ERR; estrogen-related receptor; FABP; fatty acid binding protein; FAT/CD36;
Keywords: ACC; acetyl-CoA carboxylase; ACL; ATP:citrate lyase; ACP; acyl-carrier protein; AGPase; ADP-glucose pyrophosphate; AOX; acyl-CoA oxidase; ARA; arachidonic acid; BE; branching enzymes; CDP-DAG; CDP-diacylglycerol; DAG; diacylglycerol; DGAT; diacylglycerol
Keywords: ROS; reactive oxygen species; NR; nuclear receptor; FA; fatty acid; TAG; triacylglycerol; MCD; malonyl-CoA decarboxylase; ACC; acetyl-CoA carboxylase; FAS; fatty acid synthase; SCD1; stearoyl-CoA desaturase-1; G-3-P; glycerol 3-phosphate; CPT-1; carnitine
Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio
Keywords: ACOX; acyl-CoA oxidase; ATGL; adipose triacylglyceride lipase; CAT; catalase; Cd; cadmium; CPTI; carnitine palmitoyl transferase 1; COX; cytochrome c oxidase; CsA; cyclosporin A; FAS; fatty acid synthase; 6PGD; 6-phosphogluconate dehydrogenase; G6PD; gluc
Fish oil and fenofibrate inhibit pancreatic islet hypertrophy, and improve glucose and lipid metabolic dysfuntions with different ways in diabetic KK mice
Keywords: ACC; acetyl-CoA carboxylase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AOX; acyl-CoA oxidase; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; FAS; fatty acid synthase; FF; fenofibrate; FO; fish oil; H&E; haematoxylin eosin; HO
Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway
Keywords: Ganoderic Acid A; SREBPs; Obesity; Insulin resistance; Lipid accumulation; ABCA1; ATP-binding cassette transporter 1; ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; BAT; brown adipose tissue; CPT1; carntine palmitoyltransferase 1; CYP7A1; cholesterol
A human relevance investigation of PPARα-mediated key events in the hepatocarcinogenic mode of action of propaquizafop in rats
Keywords: Propaquizafop; Carcinogenicity; Rodent hepatocarcinogenesis; PPARα; Liver; Peroxisome proliferators; Mode of action; Human relevance framework; Enzyme induction; Rats; ACO; Acyl-CoA oxidase; bw; body weight; BrdU; bromodeoxyuridine; CAT; catalase; CYP; c
A novel case of ACOX2 deficiency leads to recognition of a third human peroxisomal acyl-CoA oxidase
Keywords: ACOX; acyl-CoA oxidase; THCA; trihydroxycholestanoic acid; VLCFAs; very long-chain fatty acids; ZSD; Zellweger spectrum disorder; Bile acids; Branched-chain fatty acids; Peroxisomes; Acyl-CoA oxidase;
Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways
Keywords: Arctigenin; Lipotoxicity; Steatosis; Inflammation; Nonalcoholic fatty liver disease; ACC1; acetylcoenzyme A carboxylase 1; ACO; acyl-CoA oxidase; ATG; arctigenin; CPT-1; carnitine palmitoyltransferase 1; FAS; fatty acid synthase; MDA; malondialdehyde; NAF
The olive constituent oleuropein, as a PPARα agonist, markedly reduces serum triglycerides
Keywords: AADAC; arylacetamidedeacetylase; ACADM; acyl-CoA dehydrogenase; ACOX1; acyl-CoA oxidase; ACOT; acyl-CoA thioesterase;; ATGL; adipose triglyceride lipase; BAAT; bile acid CoA; Cd36; cluster of differentiation 36; Ces3/tgh; carboxylesterase 3; DGAT; diacylg
STAT3: The art of multi-tasking of metabolic and immune functions in obesity
Keywords: Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti
Dataset of the human homologues and orthologues of lipid-metabolic genes identified as DAF-16 targets their roles in lipid and energy metabolism
Keywords: ACAA2; Acetyl-CoA acetyltransferase 2; ACACA; Acetyl-CoA carboxylase; ACAD8; Acyl-CoA dehydrogenase family member 8; ACADM; Acyl-CoA dehydrogenase C4 to C12 straight chain; ACOX; Acyl-CoA oxidase; ACSL3/4; Acyl-CoA synthetase long-chain family member 3/4;
Increased urine acylcarnitines in diabetic ApoE-/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia
Keywords: Diabetes; Nephropathy; Hyperlipidemia; Acylcarnitine; Acyl-coenzyme A; Urine; Metabolomics; DN; diabetic nephropathy; TQM; targeted quantitative metabolomics; STZ; streptozotocin; AC; acylcarnitine (abbreviation of each AC species is given in Table S2);
Saponins from the roots of Platycodon grandiflorum ameliorate high fat diet-induced non-alcoholic steatohepatitis
Keywords: ACOX; acyl-CoA oxidase; ARE; antioxidant response element; CKS; Platycodon grandiflorum root-derived saponins; CPT-1; carnitine palmitoyltransferase-1; HFD; High fat diet; HSCs; hepatic stellate cells; NAFLD; non-alcoholic fatty liver disease; NASH; non-a
ReviewVersatility of peroxisomes: An evolving concept
Keywords: VLCFA; very long chain fatty acids; ROS; reactive oxygen species; GOX; glycolate oxidase; CAT; catalase; PMP; peroxisomal membrane protein; RNS; reactive nitrogen species; GSNOR; S-nitrosoglutathione reductase; ACOX; acyl-CoA oxidase; IPN; isopenicillin N
Genome wide identification of microRNAs involved in fatty acid and lipid metabolism of Brassica napus by small RNA and degradome sequencing
Keywords: sRNA; small RNA; miRNA; micro RNA; ACSL; long-chain acyl-CoA synthetase; DAF; day after flowering; GO; gene ontology; KEGG; terms and Kyoto Encyclopedia of Genes and Genomes; ANOVA; Analysis of Variance; qRT-PCR; Quantitative Real time PCR; ARF; auxin res
Renoprotective effect of a novel selective PPARα modulator K-877 in db/db mice: A role of diacylglycerol-protein kinase C-NAD(P)H oxidase pathway
Keywords: ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; AMPK; 5â²-AMP activated protein kinase; CPT-1; carnitine palmitoyltransferase-1; DAG; diacylglycerol; DHE; dihydroethidium; ELISA; enzyme-linked immunosorbent assay; ERR-1α; estrogen-related receptor-1
Stearoyl-CoA desaturase 1 deficiency reduces lipid accumulation in the heart by activating lipolysis independently of peroxisome proliferator-activated receptor α
Keywords: ACC; Acetyl-CoA carboxylase; ACO; Acyl-CoA oxidase; AMPK; 5â²-Adenosine monophosphate-activated protein kinase; ATGL; Adipose triglyceride lipase; BSA; Bovine serum albumin; CPT1; Carnitine palmitoyltransferase 1; DAG; Diacylglycerol; FA; Fatty acid; FFA
Chemical composition and hypoglycaemic effect of polyphenol extracts from Litchi chinensis seeds
Keywords: Litchi seeds; Diabetes; Lipid metabolism; Inflammation; Apoptosis; ACO; Acyl-CoA oxidase; AUC; area under curve; DGAT; diacyl glycerol acyl transferase; ELISA; enzyme-linked immunosorbent assay; FAS; fatty acid synthetase; FBG; fasting blood glucose; FSI;
In vivo ROS and redox potential fluorescent detection in plants: Present approaches and future perspectives
Keywords: 2-OH-E+; 2-hydroxyethidium; NO; nitric oxide; NO2; nitrogen dioxide radical; 1O2; singlet oxygen; 3O2; triplet oxygen; ACO; acyl-CoA oxidase; ALO; aldehyde oxidase; APX; ascorbate peroxidase; AsA-GSH; ascorbate-glutathione cycle; AsA; ascorbate; BODIPY; 4
Research ArticleEnhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease
Keywords: 4-HNE; 4-Hydroxynonenal; ACOX; acyl-CoA oxidase; AKT; RAC-alpha serine/threonine protein kinase; alb-myctg; transgenic mice with overexpression of c-myc in hepatocytes; ALD; alcoholic liver disease; ALT; alanine aminotransferase; Asns; asparagine syntheth
Crabapple fruit extracts lower hypercholesterolaemia in high-fat diet-induced obese mice
Keywords: Crabapple; Hyperlipidaemia; Hypercholesterolaemia; Metabolic syndrome; Anti-oxidation; CYP7A1; Procyanidin (PubChem CID: 107876); Epicatechin (PubChem CID: 72276); Isoastilbin (PubChem CID: 10114809); Quercetin 3-O-glucoside (PubChem CID: 44258003); Avicu
A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD+/NADH ratio and activating PPARα, AMPK and SIRT1 signaling pathway
Keywords: ACC; acetyl-CoA carboxylase; ACOX; acyl-CoA oxidase; AMPK; AMP-activated protein kinase; BMSO; bitter melon seed oil; c9,t11-CLA; cis-9, trans-11 isomer of conjugated linoleic acid; α-ESA; α-eleostearic acid; FASN; fatty acid synthase; FOXO1; forkhead b
iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling
Keywords: AA; arachidonic acid; Acox1; acyl-CoA oxidase; ATGL; adipocyte triglyceride lipase; CCTα; phosphate cytidylyltransferase 1, choline α; CEPT; choline/ethanolaminephosphotransferase 1; CE; cholesterol esters; CHOL; cholesterol; CM; chylomicrons; CPT1; car
Comparative effects of hawthorn (Crataegus pinnatifida Bunge) pectin and pectin hydrolyzates on the cholesterol homeostasis of hamsters fed high-cholesterol diets
Keywords: HP; haw pectin; HPH; haw pectin hydrolyzates; HPPS; haw pectin pentasaccharide; SD; standard diet; HCD; high-cholesterol diet; TC; total cholesterol; TG; triglyceride; HDL-C; high-density lipoprotein cholesterol; NEFA; nonesterified fatty acid; ACO; acyl-
New insights into the peroxisomal protein inventory: Acyl-CoA oxidases and -dehydrogenases are an ancient feature of peroxisomes
Keywords: ACAD; acyl-CoA dehydrogenase; ACOX; acyl-CoA oxidase; FAD; flavin adenine dinucleotide; MTS; mitochondrial targeting signal; Pex; peroxin; PMP; peroxisomal membrane protein; PTS; peroxisomal targeting signal; ROS; reactive oxygen species; Peroxisome; Usti
Novel role of TLR4 in NAFLD development: Modulation of metabolic enzymes expression
Keywords: NAFLD; non-alcoholic fatty liver disease; TLR; toll like receptor; LDLrKO; low density lipoprotein receptor knockout; HFD; high fat diet; Apo; apolipoprotein; MTTP; microsomal triglyceride transfer protein; GPAT; glycerol phosphate acyltransferase; ACOX;
The dipeptide H-Trp-Glu-OH (WE) shows agonistic activity to peroxisome proliferator-activated protein-α and reduces hepatic lipid accumulation in lipid-loaded H4IIE cells
Keywords: WE; H-Trp-Glu-OH; PPARs; peroxisome proliferator-activated proteins; LBD; ligand-binding domain; SPR; surface plasmon resonance; TR-FRET; time-resolved fluorescence resonance energy transfer; FATP4; fatty-acid transport protein 4; ACS; acyl-CoA synthetase
The local corticotropin-releasing hormone receptor 2 signalling pathway partly mediates hypoxia-induced increases in lipolysis via the cAMP-protein kinase A signalling pathway in white adipose tissue
Keywords: Hypoxia; Corticotropin-releasing hormone receptor 2; White adipose tissue; Lipolysis; CRHR2; corticotrophin-releasing hormone receptor type 2; Ucn2; urocortin 2; Ucn3; urocortin 3; WAT; white adipose tissue; BAT; brown adipose tissue; PKA; protein kinase
Mangiferin treatment inhibits hepatic expression of acyl-coenzyme A:diacylglycerol acyltransferase-2 in fructose-fed spontaneously hypertensive rats: a link to amelioration of fatty liver
Keywords: ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ChREBP; carbohydrate response element binding protein; CPT; carnitine palmitoyltransferase; DGAT; acyl-coenzyme A:diacylglycerol acyltransf
Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice
Keywords: ACC; acetyl-CoA carboxylase; ACOX; acyl-CoA oxidase; ACS; acyl-CoA synthetase; AK; ankaflavin; ALT; alanine aminotranferase; AMPK; AMP-activated kinase; AST; aspartate transaminase; BSA; bovine serum albumin; CPT-1; carnitine palmitoyl transferase I; CV;
Effects of combined exposure to 17α-ethynylestradiol and dibutyl phthalate on the growth and reproduction of adult male zebrafish (Danio rerio)
Keywords: 17α-Ethynylestradiol (EE2); Dibutyl phthalate (DBP); Vitellogenin; Acyl-CoA oxidase; Male zebrafish
trans-Caryophyllene is a natural agonistic ligand for peroxisome proliferator-activated receptor-α
Keywords: PPAR; peroxisome proliferator-activated receptor; LBD; ligand-binding domain; SPR; surface plasmon resonance; TR-FRET; time-resolved fluorescent resonance energy transfer; TG; triglyceride; HTG; hypertriglyceridemia; RXR; retinoid X receptor; EO; essentia
Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes
Keywords: Ad; adiponectin; NEB; negative energy balance; AdipoR1; adiponectin receptor 1; AdipoR2; adiponectin receptor 2; AMPK; AMP-activated protein kinase; PPARα; peroxisome proliferator-activated receptor α; SREBP-1c; sterol regulatory element-binding protein
Enzymatically synthesized glycogen reduces lipid accumulation in diet-induced obese rats
Keywords: ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; cDNA; complementary DNA; CHL; cholesterol; CPT; carnitine palmitoyltransferase; CT; computed tomography; ESG; enzymatically synthesized glycogen; FAS; fatty acid synthase; HF; high fat; LCAD; long-chain
Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation
Keywords: ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; ACS; acyl-CoA synthetase; AMPK; AMP-activated protein kinase; CD36; fatty acid translocase/CD36; CPT1; carnitine palmitoyltransferase 1; FA; fatty acids; NEFA; non-esterified FA; FATP1; fatty acid transp
Regulation of lipid disorders by ethanol extracts from Zingiber zerumbet in high-fat diet-induced rats
Keywords: Acyl-CoA oxidase; Cytochrome P450 isoform 4A1; High-fat diet; Peroxisome proliferator activated receptor α; Zingiber zerumbet;
Herbal medicines for the prevention of alcoholic liver disease: A review
Keywords: ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; ALD; alcoholic liver disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; AOX; acyl-CoA oxidase; CAT; catalase; COX-2;