Keywords: طولانی شدن جایگزین تلومرها; ALT; alternative lengthening of telomeres; CDK; cyclin-dependent kinase; DDR; DNA damage response; dNTP; deoxyriboNucleotide TriPhosphate; DPC; DNA-protein crosslink; DSB; double-strand break; FDA; Food and Drug Administration; HRR; homologous recombinati
مقالات ISI طولانی شدن جایگزین تلومرها (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: طولانی شدن جایگزین تلومرها; ALT; alternative lengthening of telomeres; BP; base pair; CLL; chronic lymphatic leukemia; CSS; cancer specific survival; CI; Confidence interval; DFS; disease free survival; EFS; event free survival; FISH; fluorescent in situ hybridization; GEP-NET; gast
Keywords: طولانی شدن جایگزین تلومرها; Alternative lengthening of telomeres; DNA damage; DNA repair; Epithelial-mesenchymal transition; Metastasis; Signal transduction; Telomeres; Telomere homeostasis;
Keywords: طولانی شدن جایگزین تلومرها; LSCC; laryngeal squamous cell carcinoma; ALT; alternative lengthening of telomeres; shRNAs; short hairpin RNAs; GFP; green fluorescein protein; RT-PCR; reverse transcription polymerase chain reaction; flow-FISH; flow cytometry fluorescent in situ hybridiz
Keywords: طولانی شدن جایگزین تلومرها; Telomeres; Telomerase; Human tumour cells; Gamma irradiation; DNA damage; ALT; alternative lengthening of telomeres; ANOVA; analysis of variance; CST; CTC1, STN1 and TEN1 complex; DSB; double-stranded DNA break; hTR; human telomerase RNA; PDL; population
Keywords: طولانی شدن جایگزین تلومرها; Glioma; Infiltrating glioma; Genetic; Epigenetic; Molecular; Isocitrate dehydrogenase; Epidermal growth factor receptor; Alternative lengthening of telomeres
Development of a New Monochrome Multiplex qPCR Method for Relative Telomere Length Measurement in Cancer
Keywords: طولانی شدن جایگزین تلومرها; scg; single-copy genes; mcs; multiple-copy sequences; T; telomere quantity; S; scg quantity; M; mcs quantity; DNA; deoxyribonucleic acid; PCR; polymerase chain reaction; MMQPCR; monochrome multiplex quantitative PCR; EDTA; ethylenediaminetetraacetic acid;
Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity
Keywords: طولانی شدن جایگزین تلومرها; ALT; Alternative lengthening of telomeres; APBs; ALT-associated PML bodies; BIR; Break-induced replication; CO-FISH; Chromosome orientation fluorescence in situ hybridization; DDR; DNA damage response; DOX; Doxycycline; DSBs; Double-strand breaks; HR; Hom
The role of SMARCAL1 in replication fork stability and telomere maintenance
Keywords: طولانی شدن جایگزین تلومرها; SIOD; Schimke immune-osseous dysplasia; DSB; double-stranded break; ssDNA; single-stranded DNA; RPA; replication protein A; HU; hydroxyurea; BIR; break-induced replication; ALT; alternative lengthening of telomeres; DNA replication; DNA replication stress
In vivo imaging of DNA double-strand break induced telomere mobility during alternative lengthening of telomeres
Keywords: طولانی شدن جایگزین تلومرها; ALT; alternative lengthening of telomeres; HR; homologous recombination; DSB; double-strand break; MSD; mean square displacement; ER; modified estrogen receptor domain; DD; destabilization domain; 4-OHT; 4-hydroxytamoxifen; ALT; Live cell imaging; Confoca
The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells
Keywords: طولانی شدن جایگزین تلومرها; ALT; alternative lengthening of telomeres; CST; the CTC1/STN1/TEN1 trimeric complex; APBs; ALT-associated promyelocytic leukemia bodies; PML; promyelocytic leukemia; ECTR; extrachromosomal circular telomere repeats; TC; t-circle; CC; C-circle; HDR; homolo
Interaction of Quindoline derivative with telomeric repeat-containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
Keywords: طولانی شدن جایگزین تلومرها; ALT; alternative lengthening of telomeres; ATM; ataxia telangiectasia mutated; CD; circular dichroism; ChIP; chromatin immunoprecipitation; DAPI; 4â²,6-diamidino-2-phenylindole; DDR; DNA damage response; DMSO; dimethyl sulfoxide; DSBs; DNA double-strand
Quantification of telomere features in tumor tissue sections by an automated 3D imaging-based workflow
Keywords: طولانی شدن جایگزین تلومرها; 3D-TIM; 3D Targeted Imaging; ALT; alternative lengthening of telomeres; APB; ALT-associated PML-NB; CLSM; confocal laser scanning fluorescence microscopy; ECTR; extrachromosomal telomeric repeat; FFPE; formalin-fixed, paraffin-embedded; FISH; fluorescence
ReviewTargeting telomerase and telomeres to enhance ionizing radiation effects in in vitro and in vivo cancer models
Keywords: طولانی شدن جایگزین تلومرها; TMM; telomere maintenance mechanism; T/TTC; telomere/telomerase targeting compound; G4; G-quadruplex; DSB; double strand break; ALT; alternative lengthening of telomeres; GBM; glioblastoma multiforme; AS-ODN; antisense oligonucleotide; TIF; telomere-induc
Regulated expression of the lncRNA TERRA and its impact on telomere biology
Keywords: طولانی شدن جایگزین تلومرها; TERRA; telomere repeat-containing RNA; TRF1/2; telomeric repeat-binding factors 1 and 2; POT1; protection of telomeres 1; TIN2; TRF1-interacting nuclear factor 2; TPP1; adrenocortical dysplasia protein homologue (also called ACD, PTOP, PIP1 & TINT1); RAP1
Getting it done at the ends: Pif1 family DNA helicases and telomeres
Keywords: طولانی شدن جایگزین تلومرها; DSB; double strand break; G4; G-quadruplex; TERRA; (telomere repeat containing RNA); ALT; alternative lengthening of telomeres; BIR; break induced replication; Sc; Saccharomyces cerevisiae; TA; telomere addition; CST; Cdc13-Stn1-Ten1; ChIP; chromatin immu
The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA
Keywords: طولانی شدن جایگزین تلومرها; Cancer; Telomerase; Short telomere syndromes; Biochemistry; Molecular modelling; ALT; alternative lengthening of telomeres; TERT; telomerase reverse transcriptase; TR; telomerase RNA; DKC; dyskerin; TEN; telomerase essential N-terminus; TRBD; telomerase R
DNA damage processing at telomeres: The ends justify the means
Keywords: طولانی شدن جایگزین تلومرها; 6-4PP; pyrimidine (6-4) pyrimidine photoproducts; ALT; alternative lengthening of telomeres; BER; base excision repair; CPD; cyclobutane pyrimidine dimer; DDR; DNAdamage response; DSB; DNA double strand break; dsDNA; double stranded DNA; G4; G-quadruple
High frequency of p16 and p14 promoter hypermethylation and marked telomere instability in salivary gland tumors
Keywords: طولانی شدن جایگزین تلومرها; PA; pleomorphic adenoma; CXPA; carcinoma ex pleomorphic adenoma; TSG; tumor suppressor gene; RTL; relative telomere length; ALT; alternative lengthening of telomeres; Promoter hypermethylation; p16; p14; Telomere length; Parotid gland tumors;
ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity
Keywords: طولانی شدن جایگزین تلومرها; ZSCAN4; TRF1; Cancer; Telomeres; Telomerase; ALT pathway; ALT; alternative lengthening of telomeres; BIFC; bimolecular fluorescence complementation; Co-IP; co-immunoprecipitation; ESC; embryonic stem cells; GST; glutathione S-transferase; PinX1; PIN2/TERF
Alternative lengthening of telomeres phenotype in malignant vascular tumors is highly associated with loss of ATRX expression and is frequently observed in hepatic angiosarcomas
Keywords: طولانی شدن جایگزین تلومرها; Angiosarcoma; Telomere; Alternative lengthening of telomeres; TERT; ATRX
The G-quadruplex-stabilising agent RHPS4 induces telomeric dysfunction and enhances radiosensitivity in glioblastoma cells
Keywords: طولانی شدن جایگزین تلومرها; G4; G quadruplex; TIF; telomere induced dysfunctional foci; GBM; glioblastoma multiforme; ALT; alternative lengthening of telomeres; hTERT; human telomerase catalytic subunit; PCC; premature chromosome condensation; cPDL; cumulative population doubling le
The chromatin remodeller ATRX: a repeat offender in human disease
Keywords: طولانی شدن جایگزین تلومرها; ATRX; G4-quadruplex DNA; DNA replication; alternative lengthening of telomeres
The Roles of Telomerase in the Generation of Polyploidy during Neoplastic Cell Growth
Keywords: طولانی شدن جایگزین تلومرها; CIN; chromosomal instability in neoplasia; ALT; alternative lengthening of telomeres;
Is telomerase a viable target in cancer?
Keywords: طولانی شدن جایگزین تلومرها; ALT; alternative lengthening of telomeres; hTERT; human telomerase reverse transcriptase; hTR; human telomerase RNA; TRAP; telomere repeat amplification protocol; CTL; cytotoxic T lymphocytes; NSCLC; non small cell lung cancer; HLA; human leukocyte antige
Human telomerase represses ROS-dependent cellular responses to Tumor Necrosis Factor-α without affecting NF-κB activation
Keywords: طولانی شدن جایگزین تلومرها; hTERT; human telomerase reverse transcriptase catalytic subunit; hTR; human telomerase RNA component; ROS; reactive oxygen species; TNF-α; tumor necrosis factor-α; NAC; N-acetyl-L-cysteine; CHX; cycloheximide; ERK1/2; extracellular signal-regulated kina
Telomerase activity in pleural malignant mesotheliomas
Keywords: طولانی شدن جایگزین تلومرها; Malignant mesothelioma; Telomerase; Alternative lengthening of telomeres; Immortalisation; Telomere maintenance mechanism; Pleura;
Acycloguanosyl 5â²-thymidyltriphosphate, a Thymidine Analogue Prodrug Activated by Telomerase, Reduces Pancreatic Tumor Growth in Mice
Keywords: طولانی شدن جایگزین تلومرها; Suicide Gene Therapy; Human Telomerase Reverse Transcriptase; hTERT; Telomere; ACV; acyclovir; ACV-TP-dA; acycloguanosyl 2â²-deoxy-5â²-adenosyltriphosphate; ACV-TP-dC; acycloguanosyl 5â²-cythydyltriphosphate; ACV-TP-dG; acycloguanosyl 2â²-deoxy-5â²-g
Sizing the ends: Normal length of human telomeres
Keywords: طولانی شدن جایگزین تلومرها; Telomere measurements; Telomere length heterogeneity; Heredity of telomeres; Telomerase; Alternative lengthening of telomeres;
Remarkable interference with telomeric function by a G-quadruplex selective bisantrene regioisomer
Keywords: طولانی شدن جایگزین تلومرها; Alternative lengthening of telomeres; Bisantrene; G-quadruplex; Telomerase; Telomere
PML3 interacts with TRF1 and is essential for ALT-associated PML bodies assembly in U2OS cells
Keywords: طولانی شدن جایگزین تلومرها; Alternative lengthening of telomeres; ALT-associated PML bodies; TRF1; PML3
Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers
Keywords: طولانی شدن جایگزین تلومرها; Alternative Lengthening of Telomeres; ALT activity assay; ALT-associated PML body; Telomeric circle; ALT-positive cancer;
Roles of Werner syndrome protein in protection of genome integrity
Keywords: طولانی شدن جایگزین تلومرها; γ-H2AX; phosphorylated histone H2AX; 4-NQO; 4-nitroquinoline 1-oxide; 5-OHdC; 5-hydroxycytidine; 5-OHU; 5-hydroxyuracil; 8-oxodA; 8-oxoadenine; 8-oxodG; 8-oxoguanine; ALT; alternative lengthening of telomeres; APE1; apurinic/apyrimidinic endonuclease 1;
Telomere exchange and asymmetric segregation of chromosomes can account for the unlimited proliferative potential of ALT cell populations
Keywords: طولانی شدن جایگزین تلومرها; Telomere; Cell senescence; Proliferative potential; Alternative lengthening of telomeres; ALT; Cancer; Modeling
Alternative lengthening of telomeres (ALT) and chromatin: Is there a connection?
Keywords: طولانی شدن جایگزین تلومرها; Telomere; Alternative lengthening of telomeres; Epigenetic modifications; Histone methylation; DNA methylationALT, alternative lengthening of telomeres; PML bodies, promyelocytic leukemia nuclear bodies; APBs, ALT-associated PML bodies; DNMT, DNA methyltr
Telomere dysfunction in aging and cancer
Keywords: طولانی شدن جایگزین تلومرها; hTERT; human telomerase reverse transcriptase catalytic subunit; hTR; human telomerase RNA; DSB; double-strand breaks; TRF1/2; telomere repeat binding factor 1/2; ALT; alternative lengthening of telomeres; DNA-PKcs; DNA-dependent protein kinase catalytic