Hypermethylation of the Keap1 gene inactivates its function, promotes Nrf2 nuclear accumulation, and is involved in arsenite-induced human keratinocyte transformation
Keywords: عنصر پاسخ آنتی اکسیدان; ROS; reactive oxygen species; Nrf2; nuclear factor E2-related factor 2; ARE; antioxidant response element; HO-1; heme oxygenase 1; SOD; superoxide dismutase; CAT; catalase; Keap1; Kelch-like ECH-associated protein 1; Bach1; BTB and CNC homolog 1; FBS; fet