Keywords: هستند; iNOS; nitric oxide synthase; HMGB1; high-mobility group box 1; HO-1; heme oxygenase-1; ZnPP; zinc protopor-phyrin; LPS; lipopolysaccharide; Nrf2; NF-E2-related factor 2; TNF-α; tumor necrosis factor-alpha; MAPKs; mitogen-activated protein kinases; PI3K;
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Keywords: هستند; CADs; cinnamic acid derivatives; ILs; ionic liquids; p-CA; p-coumaric acid; CA; caffeic acid; bmim; 1-butyl-3-methyl imidazolium; omim; 1-octyl-3-methyl imidazolium; PF6; hexafluorophosphate; BF4; tetrafluoroborate; TF2N; bis(trifluoromethanesulfonyl)imid
Keywords: هستند; AR; androgen receptor; ARE; androgen response element; BMP-15; bone morphogenetic protein-15; CRE; cyclic AMP (cAMP) response element; CREB; cAMP response element-binding protein, cytochrome P450 superfamily aromatase A (CYP19A) and B (CYP19B); DAX-1; Dos
Keywords: هستند; 4-HNE; 4-hydroxynonenal; 15d-PGJ2; 15-deoxy-â12,14-prostaglandin J2; AP-1; activator protein-1; As3 +; trivalent arsenite; α-SMA; a-smooth muscle actin; ARE; antioxidant response element; ATRA; all-trans retinoic acid; BDL; bile duct ligation; BHMT; b
Keywords: هستند; ROS; reactive oxygen species; Nrf2; nuclear factor erythroid 2-related factor 2; BLM; bleomycin; PF; pulmonary fibrosis; ARE; antioxidant response element; CAPE; caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester; HE; hematoxylin and eosin; SOD; su
Keywords: هستند; ARE; antioxidant response element; ATP; adenosine triphosphate; BDNF; brain-derived neurotrophic factor; CAT; catalase; COX; cyclooxygenase; CREB; cAMP-response element-binding-protein (CREB); DNA; deoxyribonucleic acid; EFE; ethyl ferulate (ethyl 4-hydro
Keywords: هستند; AEC; alveolar epithelial cell; AT2; alveolar epithelial type II; AM; alveolar macrophage; ARE; antioxidant response element; BALF; bronchoalveolar lavage fluid; JNK; c-Jun N-terminal kinase; EGFR; epidermal growth factor receptor; ECM; extracellular matri
Keywords: هستند; AhR; aryl hydrocarbon receptor; AKT/PKB; protein kinase B; AOM; azoxymethane; AP; Acticoa power; AP-1; activator protein-1; ARE; antioxidant response element; CDK; cyclins-dpendent kinase; CLPr; cacao liquor proanthocyanidins; COX-2; cyclooxygenase-2; CYP
Keywords: هستند; ACD; anemia of chronic disease; AID; absolute iron deficiency; ARE; antioxidant-responsive elements; asc; ascorbic acid; DMT1; divalent metal transporter 1; eNOS; endothelial nitric oxide synthase; EPO; erythropoietin; FBXL5; F-box and leucine-rich repeat
Keywords: هستند; ARE; antioxidant response element; APAP; acetaminophen; EGF; epidermal growth factor; ERK; Extracellular signal-regulated kinase; ECM; extracellular matrix; HO-1; heme oxygenase-1; HSC; hepatic stellate cells; HCC; hepatocellular carcinoma; ITC; isothiocy
Keywords: هستند; Bcl-2; B cell lymphoma 2; Bcl-xL; B cell lymphoma-extra large; ARE; antioxidant-response element; Cul3; cullin 3; Cyt c; cytochrome c; Drp1; dynamin-related protein 1; ERK; extracellular signal-regulated kinase; GSH; glutathione; GST; glutathione S-tran
Keywords: هستند; ARE; antioxidant response element; BVR; biliverdin reductase; CD; cytosine deaminase; DBD; DNA binding domain; Epo; erythropoietin; 5-FC; 5-fluorocytosine; GALC; galactocerebrosidase; HIF; hypoxia inducible factor; HO-1; heme oxygenase-1; HRE; hypoxia res
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration
Keywords: هستند; ER; endoplasmic reticulum; AMD; age-related macular degeneration; RPE; retinal pigment epithelium; PUFAs; polyunsaturated fatty acids; ROS; reactive oxygen species; NRF-2; nuclear factor-erythroid 2-related factor-2; ARE; antioxidant response element; Kea
Pilot-scale produced fermented lentil protects against t-BHP-triggered oxidative stress by activation of Nrf2 dependent on SAPK/JNK phosphorylation
Keywords: هستند; ACE; angiotensin I converting enzyme; ACN; acetonitrile; ARE; antioxidant response element; t-BHP; tert-butyl hydroperoxide; DCF; dichlorofluorescein; DCFDA; dichlorofluorescein diacetate; DMEM; High-glucose Dulbecco's Modified Eagle's Medium; FA; for
Bardoxolone methyl induces neuritogenesis in Neuro2a cells
Keywords: هستند; Akt; v-Akt Murine Thymoma Viral Oncogene; ARE; Antioxidant Responsive Element; BDNF; Brain Derived Neurotrophic Factor; CDDO; 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; CHOP; C/EBP homologous protein; DR5; Death Receptor 5; ERK; Extracellular signal Re
Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury
Keywords: هستند; Nuclear factor erythroid 2-related factor 2; Nod-like receptor protein 3 inflammasome; Thioredoxin1; Thioredoxin interacting protein; Inflammation; NLRP3; nod-like receptor protein 3; TXNIP; thioredoxin interacting protein; Trx1; thioredoxin1; Nrf2; nucle
Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes
Keywords: هستند; AhR; aryl hydrocarbon receptor; AP1; activating protein 1; ARE; antioxidant-response element; CAR; constitutive androstane receptor; CYP; cytochrome P450; DREs; dioxin-responsive elements; EMSA; electromobility gel shift assay; FBS; fetal bovine serum; GS
Qing brick tea (QBT) aqueous extract protects monosodium glutamate-induced obese mice against metabolic syndrome and involves up-regulation Transcription Factor Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) antioxidant pathway
Keywords: هستند; MetS; metabolic syndrome; QBT; Qing brick tea; HOMA IR; insulin resistance index; TG; triglyceride; CHO; total cholesterol; MDA; malonaldehyde; ROS; reactive oxygen species; SOD; superoxide dismutase; GPx; glutathione peroxidase; CAT; catalase; GR; glutat
Prostate-specific antigen (PSA) as a possible biomarker in non-prostatic cancer: A review
Keywords: هستند; KLK; ACPT; CAG; Siglec-9; AR; ARE; PSA; Biomarker; Cancer screening; Early detection of cancer;
Silencing of long isoforms of nuclear factor erythroid 2 like 1 primes macrophages towards M1 polarization
Keywords: هستند; ARE; antioxidant response element; ARG1; arginase 1; CCL; chemokine (C-C motif) ligand; CNC-bZIP; Cap 'n' Collar basic region leucine zipper; IFNγ; interferon gamma; IL; interleukin; LPS; lipopolysaccharide; MRC1; macrophage mannose receptor 1; NFE2L
Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches
Keywords: هستند; Tobacco heating products; In vitro; Lung epithelial; Cigarette smoke; High content screening; Reporter assay; ARE; antioxidant response element; DMSO; dimethyl sulphoxide; HCI; Health Canada intense smoking regimen; HCIm; modified Health Canada Intense s
Mkp-1 cross-talks with Nrf2/Ho-1 pathway protecting against intestinal inflammation
Keywords: هستند; ARE; antioxidant response element; BHA; butylated hydroxyanisole; CD; Crohn's disease; ChIP; Chromatin immunoprecipitation; CHX; cycloheximide; COX-2; cyclooxygenase-2; DMSO; dimethyl sulfoxide; DSS; dextran sulfate sodium; Ho-1; heme oxygenase 1; IBD; in
Effect of melatonin on attenuating the isoflurane-induced oxidative damage is related to PKCα/Nrf2 signaling pathway in developing rats
Keywords: هستند; MLT; melatonin; GSH; glutathione; SOD; superoxide dismutase; ROS; reactive oxygen species; GA; general anesthesia; Nrf2; nuclear factor erythroid 2-related factor 2; Keap 1; kelch-like EHC-associated protein 1; ARE; antioxidant response element; PKC; prot
Protective effect of ethyl acetate fraction of Drynaria quercifolia against CCl4 induced rat liver fibrosis via Nrf2/ARE and NFκB signalling pathway
Keywords: هستند; AST; Aspartate transaminase; ALT; Alanine transaminase; ALP; Alkaline phosphatase; SB; Serum Bilirubin; H & E; Hematoxylin and eosin; COX-1 & 2; Cyclooxygenase 1 & 2; LOX; Lipoxygenase; TNF- α; Tumour necrosis factor-α; α-SMA; α-smooth muscle actin; M
γ-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction
Keywords: هستند; ALT; alanine aminotransferase; ARE; antioxidant responsive element; AST; aspartate transaminase; ATRA; all--retinoid acid; CCl4; carbon tetrachloride; DCFH-DA; 2â²,7â²-dichlorofluorescin diacetate; γ-man; γ-mangostin; GSH; glutathione; HO-1; heme oxyg
Ci8 short, a novel LPS-induced peptide from the ascidian Ciona intestinalis, modulates responses of the human immune system
Keywords: هستند; LPS; LipoPolySaccharide; PBMCs; Peripheral Blood Mononuclear Cells; MHC; Major Histocompatibility Complex; ZAP-70; 70 kDa TCR ζ chain Associated Protein kinase; TCR; T Cell Receptor; iTreg; induced regulatory T cells; LAP; TGF-β1/Latency Associated Pro
Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer
Keywords: هستند; ARE; antioxidant response element; CPT1; carnitine palmitoyltransferase I; CPTII; carnitine palmitoyltransferase II; associated 9 (Cas9); clustered regulatory interspaced short palindromic repeat (CRISPR); DEN; diethyl nitrosamine; DMBA; 7, 12 dimethylben
Neuroprotection against 6-OHDA toxicity in PC12 cells and mice through the Nrf2 pathway by a sesquiterpenoid from Tussilago farfara
Keywords: هستند; 6-OHDA; 6-hydroxydopamine; Act. D; actinomycin D; AD; Alzheimer's disease; APO; apomorphine; ARE; antioxidant response element; CHX; cycloheximide; DAT; dopamine transporter; DTT; dithiothreitol; ECN; 7β-(3-ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy
Insulin is a potential antioxidant for diabetes-associated cognitive decline via regulating Nrf2 dependent antioxidant enzymes
Keywords: هستند; ARE; Nrf2-antioxidant responsive element; CAT; catalase; DMEM; Dulbecco's Modified Eagle's Medium; DMSO; dimethyl sulfoxide; DCFH-DA; 2',7'-dichlorodihydro-fluorescence diacetate; FBS; fetal bovine serum; GSH-Px; glutathione peroxidase; H2O2; hydr
Environmentally relevant concentrations of di(2-ethylhexyl)phthalate exposure alter larval growth and locomotion in medaka fish via multiple pathways
Keywords: هستند; ACh; acetylcholine; AChE; acetylcholinesterase; AP-1; activator protein-1; ARE; antioxidant response element; CAT; catalase; DEHP; di(2-ethylhexyl)phthalate; dpe; day(s) post-exposure; ERK; extracellular signal-regulated kinase; GPx; glutathione peroxidas
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro
Keywords: هستند; Nuclear factor erythroid-2-related factor 2 (Nrf2); Acetaminophen (APAP); Acute liver injury; Oxidative stress; Ginsenoside Rg1; ALT; alanine transaminase; ARE; antioxidant element; AST; aspartate transaminase; CAT; catalase; GCL; glutamate-cysteine ligas
Redox stress and signaling during vertebrate embryonic development: Regulation and responses
Keywords: هستند; ARE; antioxidant response element; BSO; buthionine sulfoximine; Eh; redox potential; GCL; glutamylcysteinyl ligase; GRX; glutaredoxin; GSH; glutathione; GSR; glutathione reductase; GSS; glutathione synthetase; GSSG; glutathione disulfide; Keap1; Kelch-lik
Acacia nilotica leaf improves insulin resistance and hyperglycemia associated acute hepatic injury and nephrotoxicity by improving systemic antioxidant status in diabetic mice
Keywords: هستند; Keap1; (Kelch-like ECH-associated protein 1); Nrf2; (Nuclear factor erythroid 2-related factor 2); ARE; (antioxidant response element); ADME; (Absorption, distribution, Metabolism, excretion); Catechol (PubChem CID: 289); Pyrogallol (PubChem CID: 1057); P
Trans-cinnamic acid attenuates UVA-induced photoaging through inhibition of AP-1 activation and induction of Nrf2-mediated antioxidant genes in human skin fibroblasts
Keywords: هستند; γ-GCLC; γ-glutamyl cysteine ligase; AMPK; 5â² AMP-activated protein kinase; AP-1; activator protein-1; ARE; antioxidant response element; CKII; casein kinase II; DAPI; 4â²,6-Diamidino-2-phenylindole dihydrochloride; DCFH2-DA; 2â²,7â²-dichlorofluores
The colourless carotenoids phytoene and phytofluene: From dietary sources to their usefulness for the functional foods and nutricosmetics industries
Keywords: هستند; ABA; abscisic acid; ABTS; 2,2-azinobis-3-ethylbenzothiazoline-6-sulfonic acid; ARE; antioxidant response element; BCAR; β-carotene; BHT; butylated hydroxytoluene; CD; control diet; CD36; cluster of differentiation 36; c.d.b.; conjugated double bonds; COX
Rubus idaeus L. (red raspberry) blocks UVB-induced MMP production and promotes type I procollagen synthesis via inhibition of MAPK/AP-1, NF-κβ and stimulation of TGF-β/Smad, Nrf2 in normal human dermal fibroblasts
Keywords: هستند; Normal human dermal fibroblasts; Ultraviolet B; Rubus idaeus L; Matrix metalloproteinase; Type I procollagen; UV; Ultraviolet; NHDFs; normal human dermal fibroblasts; RI; Rubus idaeus L.; MMP-1; matrix metalloproteinase-1; MMP-3; matrix metalloproteinase-
High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance
Keywords: هستند; AKR; aldo-keto reductase; ARE; antioxidant response element; CD44; cluster of differentiation 44; CSC; cancer stem cell; GCLC; glutamate-cysteine ligase catalytic subunit; GPX; glutathione peroxidase; GSH; glutathione; HO-1; heme oxygenase-1; HA; hyaluron
Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription
Keywords: هستند; ARE; antioxidant response element; CaMKII; Ca2+/calmodulin-dependent kinase II; GCLC; glutamate-cysteine ligase; GR; glutathione reductase; GSH; reduced glutathione; GSSG; oxidized glutathione; IκK; inhibitor of nuclear factor kappa-B kinase; Keap-1; Kel
MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2
Keywords: هستند; ARE; antioxidant response element; CK; creatine kinase; DAPI; 4â²,6â²- Diamidino-2-phenylindole; DOX; doxorubicin; ECG; electrocardiograms; FOXO3a; Forkhead box O3; GCLM; glutamate-cysteine ligase modifier subunit; GSH; glutathione; GSH-Px; glutathione
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: هستند; 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway
Keywords: هستند; ARE; antioxidative response element; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; BRCA1; breast cancer susceptibility protein 1; BRCT; BRCA1 C-terminal; BER; base excision repair; CaMKII; calcium/calmodulin-dependent protein kinase II; CNS;
The PKCδ-Nrf2-ARE signalling pathway may be involved in oxidative stress in arsenic-induced liver damage in rats
Keywords: هستند; Arsenic poisoning; Liver damage; Oxidative stress; PKCδ; Nrf2; ARE;
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease
Keywords: هستند; AGEs; advanced glycation end-products; ARE; antioxidant-response element; AP; argpyrimidine (Náº-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-l-ornithine); BBB; blood-brain barrier; Casp-3; Caspase-3; CCM; Cerebral Cavernous Malformation; CNS; central nervous
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice
Keywords: هستند; AEL; aqueous extract of L. chuanxiong rhizome; ARE; antioxidant response element; COX-2; cyclooxygenase-2; DI; didox; DN; diabetic nephropathy; EEL; ethanol extract of L. chuanxiong rhizome; ELISA; enzyme linked immunosorbent assay; ESRD; end stage renal
Cardioprotective role of azafrin in against myocardial injury in rats via activation of the Nrf2-ARE pathway
Keywords: هستند; Myocardial infarction; Ischaemia-reperfusion injury; Nrf2-ARE pathway; Azafrin; Oxidative stress; ARE; antioxidant response element; AST; aspartate aminotransferase; CK-MB; MB isoenzyme of creatine kinase; cTnI; cardiac troponin I; CVD; cardiovascular dis
The effects of Mucuna pruriens on the renal oxidative stress and transcription factors in high-fructose-fed rats
Keywords: هستند; Mucuna pruriens; High-fructose; Transcription factors; ARE; antioxidant response element; HO-1; heme-oxygenase 1; IKK; IκB kinase; Keap1; Kelch like-ECH-associated protein 1; MDA; malondialdehyde; NF-κB; nuclear factor kappa-light-chain-enhancer of acti
Up-regulation of HO-1 by Nrf2 activation protects against palmitic acid-induced ROS increase in human neuroblastoma BE(2)-M17 cells
Keywords: هستند; Neurological diseases; Heme oxygenase-1; Palmitic acid; Reactive oxygen species; BE(2)-M17 cells; AD; Alzheimer's disease; ARE; antioxidant response elements; BSA; bovine serum albumin; DHE; dihydroethidium; DCFH-DA; 2â²,7â²-Dichlorofluorescein diacetat
Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway
Keywords: هستند; Tan C; Tanshindiol C; oxLDL; oxidized low-density lipoprotein; Nrf2; NF-E2-related factor 2; ARE; antioxidant-response element; Sirt1; Sirtuin 1; Prdx1; peroxiredoxin 1; ABCA1; adenosine triphosphate-binding cassette (ABC) transporter A1; ABCG1; ATP-bindi
Discovery of natural flavonoids as activators of Nrf2-mediated defense system: Structure-activity relationship and inhibition of intracellular oxidative insults
Keywords: هستند; Isoflavone; 7-O-methylbiochanin A; Oxidative stress; Nrf2 activator; ARE; antioxidant response element; COPD; chronic obstructive pulmonary disease; γ-GCS; γ-glutamyl cysteine synthetase; GSH; glutathione; HO-1; heme oxygenase-1; Keap1; Kelch-like ECH-a
Identification of novel Nrf2 activators from Cinnamomum chartophyllum H.W. Li and their potential application of preventing oxidative insults in human lung epithelial cells
Keywords: هستند; AO; acridine orange; ARE; antioxidant response element; As(III); sodium arsenite; CC; column chromatography; CHX; cycloheximide; COPD; chronic obstructive pulmonary disease; DAPI; 6-diamidino-2-phenylindole; EB; ethidium bromide; γ-GCS; γ-glutamylcystei