Keywords: ASK1; Cytokines; Rheumatoid arthritis; Fibroblast-like synoviocytes; Inflammation;
مقالات ISI (ترجمه نشده)
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Keywords: ASK1; apoptosis signal-regulating kinase 1; ASK2; apoptosis signal-regulating kinase 2; DMSO; dimethyl sulphoxide; hERG; human ether-a-go-go-related gene; JNK; c-Jun N-terminal kinase; MKK7; mitogen activated kinase kinase 7; MTT; 3-(4,5-dimethylthiazol-2
Keywords: ATP; Adenosine 5c-triphosphate; ALT; Alanine aminotransferase; aa; Amino acid; ASK1; Apoptosis signal- regulating kinase 1; AST; Aspartate aminotransferase; BASH; Both alcoholic and non-alcoholic liver disease; CCR2/CCR5; C-C chemokine receptor types 2 an
Keywords: NASH; NAFLD; HCV; HBV; ROS; AFLD; alcoholic fatty liver disease; AMPK; adenosine monophosate-activated protein kinase; ASH; alcoholic steatohepatitis; ASK1; mitogen-activated protein kinase kinase kinase 5; ATP; adenosine triphosphate; CoA; coenzyme A;
Keywords: ASK1; apoptosis signal-regulating kinase 1; DAPI; 4â²,6 diamidino-2-phenylindole dihydrochloride; DHE; dihydroethidium; IF; immunofluorescence; JNK; c-Jun N-terminal kinase; MWM; Morris water maze; NADPH; Nicotinamide adenine dinucleotide phosphate; ROS;
Keywords: αSMA; alpha-smooth muscle actin; ABCG2; ATP-binding cassette sub-family G member 2; ACE; angiotensin-converting enzyme; ASK1; apoptosis signal-regulating kinase 1; BF; bright field; CD90; cluster of differentiation 90; CF; cardiac fibroblast; COPD; chron
Keywords: AF; S-triethyl phosphine gold(I)-2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside (Auranofin); AP-1; activator protein 1; ARE; antioxidant response element; ASK1; apoptosis signal-regulating kinase 1; [Au(dppe)2]Cl; [bis(diphenylphosphino)ethane]gold(I)
Keywords: Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells; ACE; angiotensin converting enzyme; aFGF; acidic FGF; Ang II; angiotensin II; AP-1; activating protei
Keywords: 5-HT(2B); 5-hydroxytryptamine 2B receptor; ACE; angiotensin-converting enzyme; AMPK; AMP-activated protein kinase; ARB; AT1R blocker; ASK1; apoptosis signal-regulating kinase 1; AT1R; angiotensin II type 1 receptor; ATX; autotaxin; BDL; bile duct ligation
Keywords: â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: 5-HT; 5-hydroxytryptamine; 5-HTT; 5-hydroxytryptamine transporter; AC; adenylyl cyclase; AD; Alzheimer's disease; Akt; protein kinase B; AMPAR; α-amino-3-hydroxy-5-mthhyl-4-isoxazolepropionic acid receptor; apCAM; Aplysia cell adhesion molecules; ASD;
Keywords: Thioredoxin; Redox; Oxidative stress; Signal transduction; ASK1; Cell fate;
Keywords: AMPK; 5â² adenosine monophosphate activated protein kinase; ASK1; apoptosis signal-regulating kinase 1; Atg; autophagy Related Cysteine Peptidase; BIRD-2; Bcl-2/IP3R disrupter; CaM; calmodulin; CaMKII; Ca2+/Calmodulin-dependent kinase II; Cat; Catalase;
Keywords: AP-1; activator protein 1; ASK1; apoptosis signal-regulating kinase 1; DHE; Dehydroepiandrosterone; DMEN-F12; Dulbecco's modified eagle medium; DCFH2-DA; 2â²-7â²- dichlorodihydrofluorescein diacetate; GSH; glutathione; HDA2; Histone deacetylase 2; IAA;
Keywords: ASK1; Apoptosis signal-regulating kinase 1; CNS; Central nervous system; DC; Dendritic cell; GATA3; GA-TA-binding protein-3; HIV; Human immunodeficiency virus; HL-60; Human promyelocytic leukemia cell line; IFN-γ; Interferon-γ; IL-1β; Interleukin-1β;
Keywords: Endothelial dysfunction; Endoplasmic reticulum stress; Cardiovascular risk; Chronic inflammation; AP; activator protein; ASK1; apoptosis-signaling-kinase 1; ATF; activating transcription factor; b-ZIP; basic leucine zipper; CHOP; C/EBP homologous protein;
Keywords: ALT; alanine transaminase; ASK1; apoptosis signal-regulating kinase 1; AST; aspartate transaminase; Bcl-2; B-cell lymphoma-2; CAT; catalase; COX-2; cyclooxygenase-2; DCFH-DA; 2â², 7â²-dichlorodihydrofluorescein diacetate; GP-X; glutathione peroxidase; G
Keywords: Acetaminophen; ASK1; Hepatotoxicity; c-Jun N-terminal kinase; Oxidant stress
Keywords: As1; As(Cys)3; As2; As(GS)3; As3; As(Penicilliamine)3; As4; As(SCH2CH2SO3Na)3; As5; As(Mercaptopurine)3; As6; As(2-mercaptopyridine)3; As7; As(2-mercaptopyridine N-oxide)3; ATO; arsenic trioxide; ASK1; apoptosis signal-regulating kinase-1; Cys; cysteine;
Keywords: AMPK; AMP-activated protein kinase; ASK1; apoptosis signal-regulating kinase 1; Atg; autophagy-related; ARE; AU-rich element; AUF; ARE RNA binding protein; BRF; butyrate response factor; CaMK; Ca2Â +/calmodulin-dependent protein kinase; CUGBP; CUG-binding
Keywords: ASK1; apoptosis signal-regulating kinase; ALS; amyotrophic lateral sclerosis; Apaf-1; apoptotic protease-activating factor; ATF6; activating transcription factor 6; Atg12; autophagy-related gene 12; C9ORF72; chromosome 9 open reading frame 72; CHIP; carbo
Keywords: AKAPs; A-kinase anchoring proteins; AKT; protein kinase b; Ang-II; angiotensin II; ASK1; apoptosis signal-regulating kinase 1; BH4; tetrahydrobiopterin; CaMKII; Ca/calmodulin-dependent kinase II; cGMP; cyclic guanosine monophosphate; CHF; chronic heart fa
Keywords: endoplasmic reticulum stress; unfolded protein response; retinal degeneration; cell death; apoptosis; inflammation; AMD; age-related macular degeneration; ASK1; apoptosis signal-regulating kinase 1; ATF; activating transcription factor; Bip; immunoglobuli
Keywords: 5-FU; 5-fluorouracil; AR; apoptotic resistance; ASK1; apoptosis signal-regulating kinase 1; BD,; bruceine D; COX-2; cyclooxygenase-2; EGCG,; epigallocatechin-3-gallate; EGFR,; epidermal growth factor receptor; EriB; eriocalyxin B; ERK,; extracellular sign
Keywords: APAP; Acetaminophen; AP-1; Activator protein 1; ASK1; Apoptosis signaling kinase; BMD; Benchmark dose; BMDL; Lower confidence limit of benchmark dose; BrdU; Bromodeoxyuridine; bw; Body weight; JNK1; c-Jun NH2-terminal kinase 1; CT; Carbon tetrachloride; B
Keywords: ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; BiP; binding immunoglobulin protein; bZIP; basic leucine zipper; CDK; cyclin-dependent kinase; CDKI; CD
Keywords: 2DG; 2-Deoxy-D-glucose; 2-ME; 2-methoxyestradiol; 3NP; 3-nitropropionic acid; ASK1; apoptosis signal-regulating kinase 1; Atg; autophagy-related gene; ATM; ataxia-telangiectasia mutated; Bif-1; Bax-interacting factor-1; BNIP3; Bcl-2/E1B interacting protei
Keywords: ALP; alkylphospholipid; ASK1; apoptosis signal-regulating kinase 1; CT; CTP:phosphocholine cytidylyltransferase; DISC; death-inducing signaling complex; EGF; epidermal growth factor; ER; endoplasmic reticulum; ERK; extracellular-signal-regulated kinase; J
Keywords: AGER; advanced glycosylation end product-specific receptor; ALOX5; arachidonate 5-lipoxygenase; ANT; adenine nucleotide translocase; ASK1; apoptosis signal-regulating kinase 1; aSMase; acidic sphingomyelinase; ATF6; activating transcription factor 6; CFLA
Keywords: ABC; ATP-binding cassette transporter; ASK1; apoptosis signal-regulating kinase 1; BBB; blood-brain barrier; BSO; l-buthionine-(S,R)-sulfoximine; COMT; catechol-O-methyltransferase; DA; dopamine; DAT; dopamine transporter; DHBT-1; 7-(2-aminoethyl)-3,4-d
Keywords: α-syn; α-synuclein; ASK1; Apoptosis signaling-regulating kinase 1; CMA; Chaperone-mediated autophagy; DAT; Dopamine transporter; ETC; Electron transport chain; iPS; Induced pluripotent stem; LAMP-2A; Lysosome-associated membrane protein 2A; LB; Lewy bod
Cytoprotective mechanisms of DJ-1 against oxidative stress through modulating ERK1/2 and ASK1 signal transduction
Keywords: DJ-1; Oxidative stress; Signal transduction; Cell signaling; ERK; MAPK; ASK1; Daxx; Trx1; JNK; p38;
Treatment targets for M2 microglia polarization in ischemic stroke
Keywords: PACAP; pituitary adenylate cyclase-activating polypeptide; OGA; beta-N-acetylglucosaminidase; FAM19A3; TAFA3, TAFA family (TAFA1-5); TPA; tissue plasminogen activator; GSH; glutathione-SH; NGF; nerve growth factor; BCL-2/BCL-X1; B cell leukemia/lymphoma
Involvement of NADPH oxidase 1 in UVB-induced cell signaling and cytotoxicity in human keratinocytes
Keywords: UV; Ultraviolet; ROS; Reactive Oxygen Species; O2-; Superoxide; OH; Hydroxyl radical; H2O2; Hydrogen peroxide; NOX; NADPH oxidase; PBS; Phosphate-buffered saline; DNA; Deoxyribonucleic acid; RNA; Ribonucleic acid; DPI; Diphenyleneiodonium; NAC; N-acetyl c
Age-dependent regulation of antioxidant genes by p38α MAPK in the liver
Keywords: Akt; Protein kinase B; AP-1; Activator protein-1; ASK1; Apoptosis signal-regulating kinase 1; ATF2; activating transcription factor 2;; ChIP; Chromatin immunoprecipitation;; DEN; Diethyl nitrosamine;; EGFR; Epidermal growth factor receptor; G6PDH; Glucose
The multifaceted role of glutathione S-transferases in cancer
Keywords: Glutathione-S transferase; Carcinogenesis; Biomarkers; Drug resistance; Tumor suppressor; AD; Aricaidine; AP-1; Activator protein 1; ASK1; Apoptosis signal-regulating kinase; CSC; cancer stem cells; EGFR; Epidermal growth factor receptor; GSH; glutathione
The isoflavones and extracts from Maclura tricuspidata fruit protect against neuronal cell death in ischemic injury via induction of Nox4-targeting miRNA-25, miRNA-92a, and miRNA-146a
Keywords: FME50; 50% EtOH extract of Maclura tricuspidata fruits; CFI; cudraisoflavone I; CFH; cudraisoflavone H; Nox; NADPH oxidase; OGD/Râ¯+â¯glucose; oxygen-glucose deprivation/reoxygenationâ¯+â¯glucose; MCAO/R; middle cerebral artery occlusion/reperfusion;
A MAPK/c-Jun-mediated switch regulates the initial adaptive and cell death responses to mitochondrial damage in a neuronal cell model
Keywords: AP-1; activating protein-1; ASK1; apoptosis signal-regulating kinase 1; BDNF; brain-derived neurotrophic factor; ERK; extracellular signal-regulated kinase; IEG; immediate early gene; JNK; c-Jun amino N-terminal kinase; MAPK; mitogen-associated protein ki
Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin - Thioredoxin system. 1. Understanding commonalities and differences among cell types
Keywords: ASK1; apoptosis signal-regulating kinase 1; Cat; catalase; GSH; glutathione; GPx1; glutathione peroxidase 1; Grx; glutaredoxin; KEAP1; Kelch-like ECH-associated protein 1; NRF2; nuclear factor erythroid 2-related factor 2; Prx; typical 2-Cys peroxiredoxin
Chronic exposure of the RAW246.7 macrophage cell line to H2O2 leads to increased catalase expression
Keywords: ROS; reactive oxygen species; GSH; glutathione; SOD; superoxide dismutase; PTPs; protein tyrosine phosphatases; NEM; N-ethylmaleimide; DTNB; 5,5-dithio-bis-(2-nitrobenzoic acid); PMA; phorbol 12-myristate 13-acetate; ASK1; apoptosis signal-regulating kina
JNK1 as a signaling node in VDR-BRAF induction of cell death in AML
Keywords: AP-1; Activator protein 1, c-Jun and dimerization partners; AKT; Serine/threonine protein kinase B (PKB); AML; Acute myeloid leukemia; AraC; Cytarabine/Arabinocytosine; ASK1; Apoptosis signal regulating kinase 1; BCL2; B-cell lymphoma 2; BIM; Bcl-2-like p
Gap junctional intercellular communication and endoplasmic reticulum stress regulate chronic cadmium exposure induced apoptosis in HK-2 cells
Keywords: AKT; protein kinase B; ASK1; apoptosis signal-regulating kinase 1; ER; endoplasmic reticulum; GJIC; gap junctional intercellular communication; IRE1α; inositol-requiring enzyme 1; ROS; reactive oxygen species; UPR; unfolded protein response; XBP-1s; spli
Apoptosis Signal-regulating Kinase 1 Silencing on Astroglial Inflammasomes in an Experimental Model of Ischemic Stroke
Keywords: ALS; amyotrophic lateral sclerosis; ASK1; apoptosis signal-regulating kinase 1; BSA; bovine serum albumin; CNS; central nervous system; Ct; cycling threshold; DAPI; 4â²,6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; GFAP; glial fibrillary acidic p
ER stress and cancer: The FOXO forkhead transcription factor link
Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating
Sec6 enhances cell migration and suppresses apoptosis by elevating the phosphorylation of p38 MAPK, MK2, and HSP27
Keywords: Sec6; p38 MAPK; MK2; HSP27; MAPK; Mitogen-activated protein kinases; MAP3K; MAPK kinase kinase; MAP2K; MAPK kinase; TAK1; TGFβ-activated kinase 1; ASK1; apoptosis signal-regulating kinase 1; MLK; mixed-lineage kinase; CREB; cAMP response element binding
ROS signalling in the biology of cancer
Keywords: AEJ; alternative end joining; ALL; acute lymphoblastic leukaemia; AML; acute myeloid leukaemia; Apaf-1; apoptotic protein activating factor 1; APL; acute promyelocytic leukaemia; ASK1; apoptosis signal regulating kinase 1; Bcr-Abl; breakpoint cluster-Abel
Apoptosis signal regulating kinase-1 and NADPH oxidase mediate human amylin evoked redox stress and apoptosis in pancreatic beta-cells
Keywords: ASK1; apoptosis signal regulating kinase-1; BME; β-mercaptoethanol; GSH; glutathione; hA; human amylin; hIAPP; human islet amyloid polypeptide; HFIP; hexafluoride isopropanol; JNK; c-Jun N-terminal kinase; Lac; lactacystin; MAP; mitogen activated protein
Connective tissue growth factor (CTGF) from basics to clinics
Keywords: AP1; activator protein 1; ASK1; apoptosis signal-regulating kinase 1; AT1R; angiotensin 2 type 1 receptor; AT2R; angiotensin 2 type 2 receptor; BCL-2; B-cell lymphoma 2; BMP4; bone morphogenic protein 4; BMP7; bone morphogenic protein 7; BMPs; bone morpho
A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis
Keywords: ASK1; apoptosis signal regulating kinase 1; Cul3; cullin 3; DEF; dimethylfumarate; DEM; diethylmaleate; 15d-PGJ2; 15-deoxy-Î12,14-prostaglandin J2; FBS; fetal bovine serum; 5-HI; 5-hydroxyoxindole derivative; HO-1; heme oxygenase-1; iNOS; inducible NO sy
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Keywords: Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf