Keywords: پروتون پریون سلولی; Alzheimer's disease; Amyloid-beta; Cellular prion protein; Fyn; Saracatinib;
مقالات ISI پروتون پریون سلولی (ترجمه نشده)
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Keywords: پروتون پریون سلولی; AA; amino acid; Aβo; oligomeric β-amyloid; Aβ; β-amyloid; AD; Alzheimer's disease; α7nAChR; α7 nicotinic acetylcholine receptor; ALS; amyotrophic lateral sclerosis; APLP1; amyloid beta precursor-like protein 1; APP; amyloid precursor protein; β-A
Keywords: پروتون پریون سلولی; PrPC; cellular prion protein; PrPSc; aggregated form of prion protein; NTR; N-terminal region; CTD; C-terminal domain; α2; helix 2; α3; helix 3; CD; circular dichroism; FTIR; Fourier transform infrared; DLS; dynamic light scattering; wt; wild-type; SEC;
Keywords: پروتون پریون سلولی; Polymer nanocomposites; Conducting polymers; Voltammetric sensors; Electrochemical biosensors; DPV; Differential pulse voltammetry; SWV; Square wave voltammetry; LSV; Linear sweep voltammetry; CV; Cyclic voltammetry; AdSDPV; Adsorptive stripping different
Keywords: پروتون پریون سلولی; Cellular prion protein; Natural killer cells; Activation; Cytokines;
Keywords: پروتون پریون سلولی; PrPC; cellular prion protein; PrPSc; scrapie conformer; DRM; detergent resistant membranes; GPI-AP; glycosylphosphatidylinositol-anchored proteins; ERC; endosomal recycling compartment; ERAD; endoplasmic reticulum associated-proteasomal degradation; RML;
Keywords: پروتون پریون سلولی; PrPC; cellular prion protein; PrPSc; scrapie form of prion protein; [Ca2+]i; intracellular calcium; MPs; microparticles; PMPs; platelet-derived microparticles; Thr; thrombin; PrP; prion peptide; Prion; Platelets; Intracellular calcium; Calpain; Microparti
Keywords: پروتون پریون سلولی; Cellular prion protein; Hypoxia; Lactate dehydrogenase; Monocarboxylate transporter 1; Neuroprotection;
Keywords: پروتون پریون سلولی; Neuroinflammation; Cellular prion protein; Cytokines; Vascular dementia; Vascular encephalopathy;
Keywords: پروتون پریون سلولی; Brain insulin resistance; Fructose; Cellular prion protein; NR2B subunit; Stroke;
Keywords: پروتون پریون سلولی; Cellular prion protein; SEC; IMAC; Purification; Western blot
Keywords: پروتون پریون سلولی; Aβ; amyloid-β; AD; Alzheimer's disease; ALP; autophagy-lysosome pathway; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ApoER2; apolipoprotein E receptor 2; APP; Aβ precursor protein; BDNF; brain-derived neurotrophic factor; CSF; cere
Keywords: پروتون پریون سلولی; PrPC; cellular prion protein; PrP-KO; PrP knockout; WT; wild-type; Cellular prion protein; PrP; PrP-KO; Behavior; Transgenic mice;
Keywords: پروتون پریون سلولی; Cellular prion protein; Protein subtype; PrPC heterogeneity; Protein overlay in a complex; Glycoprotein profile;
Keywords: پروتون پریون سلولی; AA; ascorbic acid; BSE; Bovine spongiform encephalopathies; B3LYP; Becke 3 parameter Lee Yang Parr; BP86; Becke Perdew86; CD; Circular dichroism; CJD; Creutzfeldt-Jakob disease; CPMD; Car-Parrinello molecular dynamics; DFT; Density functional theory;
Monomeric amyloid-β reduced amyloid-β oligomer-induced synapse damage in neuronal cultures
Keywords: پروتون پریون سلولی; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-β; PrPC; cellular prion protein; cPLA2; cytoplasmic phospholipase A2; CSP; cysteine-string protein; ELISA; enzyme-linked immunoassay; Fab; fragment antigen-binding; GPI; glycosylphosph
PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease
Keywords: پروتون پریون سلولی; Alzheimer's disease; Mouse model; Non-receptor tyrosine protein kinase; Pyk2; Src; 5XFAD; mice transgenic for human APP and presenilin1 with 5 mutations found in familial Alzheimer's disease; AAV; adeno-associated virus; Aβ; amyloid β; AD; Alzheimer's d
Monoclonal Antibody DL11C8 Identifies ADAM23 as a Component of Lipid Raft Microdomains
Keywords: پروتون پریون سلولی; ADAM23; a disintegrin and metalloprotease protein 23; CNS; central nervous system; conA; concanavalin A-Sepharose; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; PrPc; cellular prion protein; TNF; tumor necrosis factor; WGA; wheat germ a
Residue-specific mobility changes in soluble oligomers of the prion protein define regions involved in aggregation
Keywords: پروتون پریون سلولی; Prion protein; Protein misfolding; Beta oligomer; Solution NMR; PrPSc; infectious particle of misfolded prion protein; PrP; prion protein; PrPc; cellular prion protein; BSE; bovine spongiform encephalopathy; CWD; chronic wasting disease; CJD; Creutzfeldt
PrPC expression and calpain activity independently mediate the effects of closed head injury in mice
Keywords: پروتون پریون سلولی; Cellular prion protein; Calpain; Closed head injury; Traumatic brain injury; SNJ-1945;
The metalloproteinase ADAM10: A useful therapeutic target?
Keywords: پروتون پریون سلولی; APL; Acute Promyelocytic Leukemia; ADAM; A Disintegrin And Metalloproteinase; AP2; Adaptor Protein-2; AD; Alzheimer's Disease; Aβ; Amyloid beta; APP; Amyloid Precursor Protein; ACE; Angiotensin Converting Enzyme; APRIL; A Proliferation-Inducing Ligand; B
l-Arginine ethylester enhances in vitro amplification of PrPSc in macaques with atypical L-type bovine spongiform encephalopathy and enables presymptomatic detection of PrPSc in the bodily fluids
Keywords: پروتون پریون سلولی; Atypical bovine spongiform encephalopathy; Protein misfolding cyclic amplification; Arginine ethylester; Bodily fluid; Nonhuman primate; PrPSc; Pathogenic form of prion protein; PrPC; cellular prion protein; CJD; Creutzfeldt-Jakob disease; BSE; Bovine s
Electrochemical detection of amyloid-β oligomer with the signal amplification of alkaline phosphatase plus electrochemical–chemical–chemical redox cycling
Keywords: پروتون پریون سلولی; Amyloid-β oligomer; Cellular prion protein; Electrochemical biosensor; Alkaline phosphatase; Redox cycling
Protein misfolding cyclic amplification (PMCA): Current status and future directions
Keywords: پروتون پریون سلولی; TSEs; transmissible spongiform encephalopathies; PrPTSE; disease associated misfolded PrP; PrPC; cellular prion protein; PrPres; proteinase K resistant misfolded PrP; PrP27-30; proteinase K resistant core of misfolded PrP; rPrP; recombinant PrP; PMCA; p
Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing
Keywords: پروتون پریون سلولی; AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-
Molecular cloning and sequence analysis of prion protein gene in Xiji donkey in China
Keywords: پروتون پریون سلولی; TSEs; transmissible spongiform encephalopathies; CJD; Creutzfeldt-Jakob disease; vCJD; variant Creutzfeldt-Jakob diseases; BSE; bovine spongiform encephalopathy; CWD; chronic wasting disease; FME; feline spongiform encephalopathy; TME; mink spongiform
De novo galectin-3 expression influences the response of melanoma cells to isatin-Schiff base copper (II) complex-induced oxidative stimulus
Keywords: پروتون پریون سلولی; [Cu(isaepy)2](ClO4)2; [bis-(2-oxindol-3-yl-imino)-2-(2-aminoethyl) pyridine-N,N'] copper (II) perchlorate; [Zn(isaepy)Cl2]; [dichloro (2-oxindol-3-yl-imino)-2-(2-aminoethyl) pyridine-N,Nâ²] zinc (II); AMPK; adenosine monophosphate-activated protein kin
Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP
Keywords: پروتون پریون سلولی; CAD; collisionally activated dissociation; CHO; Chinese hamster ovary; GPI; glycosylphosphatidylinositol; MS; mass spectrometry; MS/MS; tandem mass spectrometry; PRNP; the gene encoding the prion protein; PrPC; cellular prion protein; PrPSc; scrapie isofo
Persistence of the bovine spongiform encephalopathy infectious agent in sewage
Keywords: پروتون پریون سلولی; BSE; bovine spongiform encephalopathy; CWD; chronic wasting disease; TSE; transmissible spongiform encephalopathies; PrPc; cellular prion protein; PrPSc; scrapie-associated prion protein; PrPRes; protease-resistant prion protein; Prions; BSE; PrPRes; Infe
Overexpression of cellular prion protein (PrPC) prevents cognitive dysfunction and apoptotic neuronal cell death induced by amyloid-β (Aβ1-40) administration in mice
Keywords: پروتون پریون سلولی; Aβ; amyloid-β; AD; Alzheimer's disease; ANOVA; analysis of variance; Ca2+; calcium; DMSO; dimethyl sulfoxide; E; east; i.c.v.; intracerebroventricular; i.p.s.p.; inhibitory postsynaptic potentials; K+; potassium; KRB; Krebs-Ringer bicarbonate buffer
Developmental expression of cellular prion protein and apoptotic molecules in the rat cerebellum: Effects of platinum compounds
Keywords: پروتون پریون سلولی; cisPt; cisplatin; EGL; external granular layer; IGL; internal granular layer; ML; molecular layer; PCL; Purkinje cell layer; PD; postnatal day; PrPc; cellular prion protein; Pt; platinum; PtAcacDMS; [Pt(O,Oâ²-acac)(γ-acac)(DMS)]; Cellular prion protein;
Prolongation of prion disease-associated symptomatic phase relates to CD3+ T cell recruitment into the CNS in murine scrapie-infected mice
Keywords: پروتون پریون سلولی; PrPc; cellular prion protein; PrPSc; prion protein scrapie; rAd; recombinant adenovirus; TSE; transmissible spongiform encephalopathy; AA; amino acid; Wt; wild-type; CTL; cytotoxic T lymphocytes; CNS; central nervous system; OligoCpG; oligodeoxy nucleotid
Molecular cloning and polymorphism analysis of the prion protein gene in Tan sheep of Ningxia, China
Keywords: پروتون پریون سلولی; TSE; transmissible spongiform encephalopathies; CJD; Creutzfeldt-Jakob disease; BSE; bovine spongiform encephalopathy; PrP; prion protein; PrPc; cellular prion protein; PRNP; prion protein gene; SNPs; single nucleotide polymorphisms; ARQ; A136R154Q171;
Salt bridges in prion proteins are necessary for high-affinity binding to the monoclonal antibody T2
Keywords: پروتون پریون سلولی; BSE; bovine spongiform encephalopathy; CD; circular dichroism; ka; association rate constant; kd; dissociation rate constant; KD; dissociation constant; PAGE; polyacrylamide gel electrophoresis; PrP; prion protein; PrPC; cellular prion protein; PrPSc; abn
Cellular prion protein (PrPC) and superoxide dismutase (SOD) in vascular cells under oxidative stress
Keywords: پروتون پریون سلولی; Superoxide dismutase; Cellular prion protein; Rabbit aortic smooth muscle cells; Copper concentration; Endoplasmic reticulum stress
Resistance against apoptosis by the cellular prion protein is dependent on its glycosylation status in oral HSC-2 and colon LS 174T cancer cells
Keywords: پروتون پریون سلولی; Cellular prion protein; N-linked glycosylation; Tunicamycin; Cancer; Oxidative stress
Cellular prion protein in the central nervous system of mammals. Anatomoclinical associations
Keywords: پروتون پریون سلولی; Cellular prion protein; Prionopathies; Alzheimer's disease; Mammals; ProteÃna priónica celular; PrionopatÃas; Enfermedad de Alzheimer; MamÃferos;
Cellular prion protein overexpression disturbs cellular homeostasis in SH-SY5Y neuroblastoma cells but does not alter p53 expression: a proteomic study
Keywords: پروتون پریون سلولی; prion protein; signal transduction; cytoskeleton; protein folding; annexin V; transgelin 2; ADHX; alcohol dehydrogenase class III; ANXA5; annexin V; CV028; UPF0027 protein; DMEM; Dulbecco's modified Eagle medium; FCS; fetal calf serum; FKBP4; FK506-bindin
Characterization of a specific interaction between ADAM23 and cellular prion protein
Keywords: پروتون پریون سلولی; Disintegrin; Metalloprotease; ADAM23; Cellular prion protein; Prions; Glycosylation
The role of glycophosphatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro
Keywords: پروتون پریون سلولی; Transmissible spongiform encephalopathy; Prion; Prion protein; Conformational conversion; Glycophosphatidylinositol anchor; GPI; glycophosphatidylinositol; NBH; normal hamster brain homogenate; PI-PLC; phosphatidylinositol-specific phospholipase C; PK; pr
Enhanced prion protein stability coupled to DNA recognition and milieu acidification
Keywords: پروتون پریون سلولی; PrP; prion protein; PrPSc; prion scrapie; mrPrP; recombinant murine prion protein; PrPC; cellular prion protein; TSEs; transmissible spongiform encephalopathies; GdmCl; guanidinium chloride; NA; nucleic acid.; Prion; DNA; Stability; Unfolding; pH; Urea; G
Cellular prion protein modulates age-related behavioral and neurochemical alterations in mice
Keywords: پروتون پریون سلولی; aging; cellular prion protein (PrPC); behavior; acetylcholinesterase (AChE); synaptophysin; caspase-3; AChE; acetylcholinesterase; AD; Alzheimer's disease; ANOVA; analysis of variance; DAB; 3,3â²-diaminobenzidine; DG; dentate gyrus; DTNB; dithiobisnitrob
Cellular prion protein in mammary gland and milk fractions of domestic ruminants
Keywords: پروتون پریون سلولی; Apocrine secretion; Cellular prion protein; Mammary gland; Milk
Research ReportMild cognitive deficits associated to neocortical microgyria in mice with genetic deletion of cellular prion protein
Keywords: پروتون پریون سلولی; PrPC; cellular prion protein; Prnp; gene that codify PrPC protein; Prnp+/+; PrPC expressing mouse; Prnp0/0; PrPC-null mice; FL; freeze-lesion; MCD; malformation of cortical development; LTP; long-term potentiation; LTM; long-term memory; STM; short-term m
CRBL cells: Establishment, characterization and susceptibility to prion infection
Keywords: پروتون پریون سلولی; PrP; prion protein; PrPC; cellular prion protein; PrPSc; scrapie prion protein disease; CJD; Creutzfeldt-Jakob; p53â/â; p53 null; CRBL; a cell line established from the cerebellum; N2a; Neuro2a; ScN2a; scrapie-infected N2a; SMB; scrapie-infected mouse
The ubiquitin-proteasome system in spongiform degenerative disorders
Keywords: پروتون پریون سلولی; AD; Alzheimer's disease; AgRP; Agouti related protein; AIDS; acquired immune deficiency syndrome; APP; amyloid precursor protein; ASPA; aspartoacylase gene; Atrn; attractin; BSE; bovine spongiform encephalopathy; CD; Canavan's spongiform leukodystroph
Involvement of cellular prion protein in the nociceptive response in mice
Keywords: پروتون پریون سلولی; Cellular prion protein; Thermal and chemical nociception; Inflammation;
Cellular prion protein regulates the motor behaviour performance and anxiety-induced responses in genetically modified mice
Keywords: پروتون پریون سلولی; Cellular prion protein; Motor behaviour; Plus-maze test; Open field test; Rota-rod test; Anxiety
The neurochemical nature of PrPc-containing cells in the rat brain
Keywords: پروتون پریون سلولی; CB; calbindin; CBP; calcium-binding proteins; CJD; Creutzfeldt-Jakob disease; CR; calretinin; FFI; Fatal Familial Insomnia; PNN; perineuronal nets; PrPC; cellular prion protein; PrPSc; scrapie prion protein; PV; parvalbumin; TSEs; transmissible spongiform
Short-term memory formation and long-term memory consolidation are enhanced by cellular prion association to stress-inducible protein 1
Keywords: پروتون پریون سلولی; Cellular prion protein; STI1; Memory; Learning