دانلود مقالات ISI درباره Cmax + ترجمه فارسی

Polysialic acid-modifying liposomes for efficient delivery of epirubicin, in-vitro characterization and in-vivo evaluation

Keywords: AUC(0-t); area under the drug concentration-time curve values; Cmax; maximum concentration; CLz; total clearance; DiR; 1,1′-dioctadecyl-3,3,3′,3′-tetramethyl indotricarbocyanine iodide; DiR-CL; DiR-labeled common liposomes; DiR-SL; DiR-labeled PSA-B

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Neuropharmacological efficacy of the traditional Japanese Kampo medicine yokukansan and its active ingredients

Keywords: Aβ; amyloid β; AD; Alzheimer's disease; ADL; activities of daily living; BBB; blood-brain barrier; BPSD; behavioral and psychological symptoms of dementia; BrdU; bromodeoxyuridine; Cmax; maximum concentration; CHOP; C/EBP homologous protein; CYP; cyto

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

1-Alpha, 25-dihydroxyvitamin D3 alters the pharmacokinetics of mycophenolic acid in renal transplant recipients by regulating two extrahepatic UDP-glucuronosyltransferases 1A8 and 1A10

Keywords: AcMPAG; acyl mycophenolic acid glucuronide; ChIP; chromatin immunoprecipitation; Cmax; maximum concentration; DR; direct repeat; MMF; mycophenolate mofetil; MPA; mycophenolic acid; MPAG; mycophenolic acid glucuronide; PK; pharmacokinetics; PD; pharmacodyn

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Gastrodia elata and epilepsy: Rationale and therapeutic potential

Keywords: Epilepsy; Gastrodia elata; Gastrodin; Phenolic compounds; Anticonvulsant properties; AED; antiepileptic drug; AUC; area under the concentration-time curve; Cmax; peak plasma concentration; CNS; central nervous system; ED50; median effective dose; G. elata

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Rhinitis, sinusitis, and upper airway diseaseShort-term subcutaneous grass pollen immunotherapy under the umbrella of anti-IL-4: A randomized controlled trial

Keywords: Allergic rhinitis; subcutaneous allergen immunotherapy; anti-IL-4; FluoroSpot; intradermal late-phase response; AE; Adverse event; AIT; Allergen immunotherapy; Cmax; Maximum drug plasma concentration; CRTH2; Chemoattractant receptor-homologous molecule

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

Tolerability, exposure and pharmacokinetics in healthy subjects of a Chinese herbal medicine MaZiRenWan (MZRW): Study protocol for a randomized open-labelled, three-arm phase 0/1 clinical trial

Keywords: MZRW; MaZiRenWan; AUC; the area under the plasma concentration-time curve; Cmax; the peak plasma concentration of an ingredient after administration; tmax; the time to reach Cmax; t1/2; the elimination half-life; CL; clearance; ADME; the absorption, distr

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study

Keywords: ACN; acetonitrile; AD; Alzheimer disease; AUCtotal; area under curve/bioavailability; CAS; catalytic anionic site; Cmax; maximal plasma concentration; CL; clearance; FDA; US Food and drug administration; hAChE/AChE; human acetylcholinesterase/acetylcholin

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

LC-MS/MS for Therapeutic Drug Monitoring of anti-infective drugs

Keywords: Liquid chromatography-tandem mass spectrometry (LC-MS/MS); Therapeutic Drug Monitoring (TDM); Pharmacokinetics/pharmacodynamics (PK/PD); Anti-infectives; Matrix effects; Antimicrobial stewardship (AMS); Free drug concentration; Laboratory proficiency test

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Use of response surface methodology to determine optimum diets for Venerupis corrugata larvae: effects of ration and microalgal assemblages

Keywords: b0; Constant coefficient of the model; bi; Coefficient of linear effect of the model; bij; Coefficient of interaction effect of the model; bii; Coefficients of squared effect of the model; I; Isochrysis galbana; Imax; Concentration of I. galbana that maxi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Andrographis paniculata: Dissolution investigation and pharmacokinetic studies of four major active diterpenoids after multiple oral dose administration in healthy Thai volunteers

Keywords: 1; andrographolide; 2; 14-deoxy-11, 12-didehydroandrographolide; 3; neoandrographolide; 4; 14-deoxyandrographolide; AUC; area under plasma concentration-time curve; Cmax; maximum concentration; Cl; clearance; EDTA; ethylenediaminetetraacetic acid; F; bioa

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Bioequivalence and food effect of heat-stressed and nonâ¿¿heat-stressed dapagliflozin 2.5- and 10-mg tablets

Keywords: AUC0â¿¿t; area under the plasma concentrationâ¿¿time curve from time 0 to the last quantifiable concentration; AUC0â¿¿inf; area under the plasma concentrationâ¿¿time curve from time 0 to infinity; Cp; plasma concentration; Cmax; maximum Cp; Dapagliflozin;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Drug-induced cholestasis risk assessment in sandwich-cultured human hepatocytes

Keywords: BAs; bile acids; Cmax; maximum plasma concentration; CDF(DA); 5-(6)-carboxy-2′,7′-dichlorofluorescein (diacetate); DIC(I); drug-induced cholestasis (index); DILI; drug-induced liver injury; IMI; Innovative Medicine Initiative; MIP-DILI; Mechanism-Base

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Stable loading and delivery of disulfiram with mPEG-PLGA/PCL mixed nanoparticles for tumor therapy

Keywords: DSF; disulfiram; mPEG-PLGA; methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide); PCL; poly(ε-caprolactone); NPs; nanoparticles; DMF; N,N′-dimethylformamide; CH3CN; acetonitrile; DLS; dynamic light scattering; TEM; transmission electron microscop

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2016 سفارش ترجمه

Combined therapy using bevacizumab and turmeric ethanolic extract (with absorbable curcumin) exhibited beneficial efficacy in colon cancer mice

Keywords: Bevacizumab; Colorectal cancer; Curcumin; Turmeric; Turmerone; 5-FU; 5-fluorouracil; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under concentrationâ¿¿time curve; Cmax; maximum concentration; CK; creatine kinase; FBS; fetal b

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

Quercetin-loaded freeze-dried nanomicelles: Improving absorption and anti-glioma efficiency in vitro and in vivo

Keywords: ATCC; American Tissue Culture Collection; BBB; blood-brain barrier; CMC; critical micelle concentration; DL; drug loading; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DPH; 1,6-diphenyl-1,3,5-hexatriene; EE; encapsulation efficiency

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: The case of kidney toxicity induced by aristolochic acid I

Keywords: Physiologically based kinetic (PBK) model; Aristolochic acid I (AAI); Kidney toxicity; In vitro-in vivo extrapolation; Risk assessment; Physiologically based pharmacokinetic (PBPK) model; AA; aristolochic acid; AAI; aristolochic acid I; AAII; aristoloch

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacokinetic synergy from the taxane extract of Taxus chinensis improves the bioavailability of paclitaxel

Keywords: Taxus chinensis var. mairei; Paclitaxel; Bioavailability; Pharmacokinetic synergy; Tissue distribution; Cytotoxicity; PTX; paclitaxel; P-gp; P-glycoprotein; CYP; cytochrome P450; MRP2; multidrug resistance protein 2; Cmax; peak plasma concentration; Tmax;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Dietary pretreatment with green tea polyphenol, (−)-epigallocatechin-3-gallate reduces the bioavailability and hepatotoxicity of subsequent oral bolus doses of (−)-epigallocatechin-3-gallate

Keywords: ALT; alanine aminotransferase; AUC0→6h; exposure over 6 h; Cmax; maximum concentration; EGCG; (−)-epigallocatechin-3-gallate; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GPX; glutathione peroxidase; GSR; glutatione reductase; GST; glutathione-S

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

High-performance liquid chromatography-tandem mass spectrometry method for the determination of perampanel, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist in human plasma

Keywords: AED; anti-epileptic drugs; AMPA; α-amin-3-hydroxyl-5methyl-4isoxazolepropionic acid; AUC; area under the plasma concentration-time curve; AUC0-inf; AUC extrapolated to infinity; AUC0-last; AUC to the last time points; AUMC; area under the first mom

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of the toxicology and pharmacokinetics of recombinant factor VIII Fc fusion protein in animals

Keywords: aPTT; activated partial thromboplastin time; AUC∞; area under the curve from zero to time infinity; AUClast; area under the curve up to the last measurable concentration; BW; body weight; CL; clearance; Cmax; maximum plasma concentration; ECG; electroca

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticlePharmacokinetics and safety of co-administered paritaprevir plus ritonavir, ombitasvir, and dasabuvir in hepatic impairment

Keywords: HCV; hepatitis C virus; Cmax; maximal plasma concentration; AUC; area under the plasma concentration-time curve; DAA; direct-acting antiviral agent; NS; nonstructural; CYP; cytochrome P450; Paritaprevir/r; paritaprevir administered with ritonavir; SVR12;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of the toxicology, pharmacokinetics, and local tolerance of recombinant factor IX Fc fusion protein in animals

Keywords: aPTT; activated partial thromboplastin time; AUClast; area under the time versus plasma concentration curve from the time of dose administration to the last measurable concentration; BW; body weight; CL; clearance; Cmax; maximum plasma concentration; ECG;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Pharmacoscintigraphy studies to assess the feasibility of a controlled release formulation of ziprasidone

Keywords: AUCinf; area under the serum concentration-time profile from time 0 extrapolated to infinite time; BA; bioavailability; Cmax; maximum serum concentration; Tmax; time for Cmax; SCT; swellable core technology; CCSD; coated crystals made by spray drying; IR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of the Plasmatic and Parenchymal Elution Kinetics of Two Different Irinotecan-Loaded Drug-Eluting Embolics in a Pig Model

Keywords: AUC; area under the curve; Cmax; maximum concentration;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Idarubicin-Loaded ONCOZENE Drug-Eluting Embolic Agents for Chemoembolization of Hepatocellular Carcinoma: In Vitro Loading and Release and In Vivo Pharmacokinetics

Keywords: AE; adverse event; AUC0-24 h; area under the concentration-time curve from 0-24 hours; Cmax; maximum concentration; DEE; drug-eluting embolic; HCC; hepatocellular carcinoma; LLOQ; lower limit of quantification; MDR; multidrug resistance; PK; pharmacok

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Lack of effect of perampanel on QT interval duration: Results from a thorough QT analysis and pooled partial seizure Phase III clinical trials

Keywords: AE; adverse event; AED; antiepileptic drug; ANOVA; analysis of variance; AUC; area under the concentration-time curve; BMI; body mass index; CI; confidence interval; Cmax; maximum plasma concentration; ECG; electrocardiogram; hERG; human ether-à-go-go-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of the dopamine β-hydroxylase (DβH) inhibitor nepicastat in participants who meet criteria for cocaine use disorder

Keywords: Cocaine; Dopamine-β-hydroxylase; Nepicastat; SYN117; AE; Adverse Event; ANOVA; Analysis of Variance; AUC; Area Under the Curve; BP; Blood Pressure; Cmax; Maximum Concentration; DA; Dopamine; DβH; Dopamine-β-hydroxylase; DSM; Diagnostic and Statistical

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Safety and Tolerability of Omecamtiv Mecarbil During Exercise in Patients With Ischemic Cardiomyopathy and Angina

Keywords: exercise tolerance; heart failure; ischemic cardiomyopathy; omecamtiv mecarbil; AE; adverse event; Cmax; maximum plasma concentration; CPK; creatine phosphokinase; ECG; electrocardiogram; ETT; exercise treadmill test; IV; intravenous; LV; left ventricula

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Preclinical pharmacokinetic evaluation and metabolites identification of methyl salicylate-2-O-β-d-lactoside in rats using LC-MS/MS and Q-TOF-MS methods

Keywords: AS; salicylic acid; AUC; area under the blood concentration-time curve; Cmax; maximum concentration; ESI; electrospray ionization; IS; internal standard; LC-MS/MS; liquid chromatography-mass spectrometry/mass spectrometry; MSL; methyl salicylate-2-O-β-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleDrug-drug interaction profile of the all-oral anti-hepatitis C virus regimen of paritaprevir/ritonavir, ombitasvir, and dasabuvir

Keywords: PTV/r; paritaprevir/ritonavir; OBV; ombitasvir; DSV; dasabuvir; DAA; direct-acting antiviral agent; HCV; hepatitis C virus; Cmax; maximum observed plasma concentration; AUC; area under the plasma concentration-time curve; SVR; sustained virologic response

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms and latest clinical studies of new NK1 receptor antagonists for chemotherapy-induced nausea and vomiting: Rolapitant and NEPA (netupitant/palonosetron)

Keywords: AE; adverse event; AUC; area under the curve; 5-HT3; serotonin subtype 3; CINV; chemotherapy-induced nausea/vomiting; Cmax; maximum serum concentration; CNS; central nervous system; CR; complete response; CYP; cytochrome P450; ECG; electrocardiogram; FLIE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A randomised, placebo-controlled, Phase II, dose-ranging trial of once-daily treatment with olodaterol, a novel long-acting β2-agonist, for 4 weeks in patients with chronic obstructive pulmonary disease

Keywords: Olodaterol; COPD; Long-acting β2-agonist; Once-daily; AE; adverse event; AUC0-6; area under the curve from 0 to 6 h; COPD; chronic obstructive pulmonary disease; Cmax; maximum concentration; FEV1; forced expiratory volume in 1 s; FVC; forced vital ca

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiovascular pharmacologyCardiovascular safety pharmacology profile of etamicastat, a novel peripheral selective dopamine-ß-hydroxylase inhibitor

Keywords: DBH; dopamine-ß-hydroxylase; LC-MS/MS; liquid chromatography - mass spectrometry; AUC; area under plasma concentration-time curve; tmax; time to maximum concentration; t1/2; terminal half-life; Cmax; maximum concentration; LLOQ; lower limit of quanti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of EGCG content in green tea extract on pharmacokinetics, oxidative status and expression of inflammatory and apoptotic genes in the rat ocular tissues

Keywords: AUC; area under curve; Cmax; maximum concentration; EC; (−)-epicatechin; EGC; (−)-epigallocatechin; EGCG; (−)-epigallocatechin gallate; GC; (−)-gallocatechin; GCG; (−)-gallocatechin gallate; GPx3; glutathione peroxidase-3; GSH; reduced glutathio

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

A randomized, three-period crossover study of umeclidinium as monotherapy in adult patients with asthma

Keywords: Asthma; Fixed-dose combination; Muscarinic antagonist; Inhaled corticosteroid; Trough FEV1; Ae; amount of dose excreted unchanged in urine; AE; adverse event; ALT; alanine aminotransferase; AUC; area under the curve; BID; twice daily; bpm; beats per minut

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

New insights into the bioavailability of red raspberry anthocyanins and ellagitannins

Keywords: ADME; absorption, disposition, metabolism and excretion; Cmax; peak plasma concentration; CID; collision-induced dissociation; ESI; electrospray interface; GIT; gastrointestinal tract; PDA; photodiode array; Tmax; time to reach peak plasma concentration;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Les bases pharmacologiques de la thérapeutique. Analyse pharmacologique du résumé des caractéristiques d'un produit ( le « RCP ») pour le thérapeute

Keywords: résumé des caractéristiques d'un produit; RCP; pharmacologie; thérapeutique; summary of product caracteristics; SPC; pharmacology; therapeutics; AMM; autorisation de mise sur le marché; ANSM; Agence Nationale de Sécurité du Médicament et des pro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Toxicological evaluation of two flavors with modifying properties: 3-((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)-2,2-dimethyl-N-propylpropanamide and (S)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1

Keywords: AUC; area under the curve; CL; plasma clearance; Cmax; peak plasma concentration; EIC; extracted ion chromatogram; FDA; Food and Drug Administration; FEMA; Flavor and Extract Manufacturers Association of the United States; FL-no; FLAVIS number; FMP; flavo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Advances and challenges in PBPK modeling - Analysis of factors contributing to the oral absorption of atazanavir, a poorly soluble weak base

Keywords: API; active pharmaceutical ingredient; ART; antiretroviral therapy; AUC; area under the curve; BCRP; breast cancer resistance protein; BCS; biopharmaceutics classification system; Caco-2; heterogeneous human epithelial colorectal adenocarcinoma cells; Cma

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Reliability of the TTC approach: Learning from inclusion of pesticide active substances in the supporting database

Keywords: AChE; acetylcholinesterase; ADI; Acceptable Daily Intake; ChE; cholinesterase; Cmax; peak plasma concentration achieved after administration of a substance; DAR; Draft Assessment Report; EC; European Commission; EEG; electroencephalogram; EFSA; European F

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Comparison of physiologic and pharmacologic parameters in Asian and mauritius cynomolgus macaques

Keywords: Cynomolgus macaque; Background parameters; Physiologic comparison; Pharmacologic comparison; Asian macaque; Mauritius macaque; AUC; area under the curve; Cmax; maximum concentration; ELISA; Enzyme-Linked Immunosorbent Assay; KLH; keyhole limpet hemocyanin

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Intranasal microemulsion for targeted nose to brain delivery in neurocysticercosis: Role of docosahexaenoic acid

Keywords: ABZ; albendazole; ABZ-SO; Albendazole sulfoxide; ACN; acetonitrile; ALP; alkaline phosphatase; ANOVA; analysis of variance; AUC; area-under-the-curve; BBB; blood brain barrier; Cmax; maximum concentration; CUR; Curcumin; CYPs; cytochrome P450; DHA; docosa

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2)

Keywords: ABC; ATP-binding cassette; ALK; anaplastic lymphoma kinase; AUC; area under the plasma concentration-time curve; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; Cmax; maximum drug concentration in plasma; EML4; echinoderm microtubule-ass

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

Adaptation of the quality by design concept in early pharmaceutical development of an intranasal nanosized formulation

Keywords: API; active pharmaceutical ingredient; Cmax; maximum plasma concentration; CQA; critical quality attribute; CPP; critical process parameter; EMA; European Medicines Agency; FDA; Food and Drug Administration; HA; sodium hyaluronate; ICH; International Conf

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2015 سفارش ترجمه

Current knowledge and pharmacological profile of berberine: An update

Keywords: 5-HT; 5-hydroxytryptamine; 6-OHDA; 6-hydroxydopamine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; BBB; blood brain barrier; BChE; butyrylcholinestesrase; CD; cluster of differentiation; Cdk; cyclin-dependent ki

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Human systemic exposure to [14C]-paraphenylenediamine-containing oxidative hair dyes: Absorption, kinetics, metabolism, excretion and safety assessment

Keywords: AA; arylamine(s); AUC; area under the curve; BMI; body mass index; bw; body weight; Cmax; maximal plasma concentration; HPLC/MS/MS; high performance liquid chromatography-tandem/mass spectrometry; IARC; International Agency for the Research of Cancer; Ke;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

14th Annual Meeting of the Safety Pharmacology Society: Threading through peripheral and central nervous system presentations

Keywords: Aβ; Aβ-amyloid protein; AANEM; American Academy of Neuromuscular and Electrodiagnostic Medicine; AAN; American Academy of Neurology; AD; Alzheimer's Disease; API; Alzheimer's Prevention Initiative-APOE4; ADF; Abuse Deterrent Formulations; ADNI; Alzheime

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of the potent and selective DP1 receptor antagonist, asapiprant (S-555739), in animal models of allergic rhinitis and allergic asthma

Keywords: AHR; airway hyper-responsiveness; AUC; area under the curve; BALF; bronchoalveolar lavage fluid; cAMP; cyclic adenosine monophosphate; CRTH2; chemoattractant receptor homologous molecule expressed on Th2 cells; Cmax; maximum concentration achieved after d

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2015 سفارش ترجمه

Ex vivo reversal of the anticoagulant effects of edoxaban

Keywords: aPTT; Activated partial thromboplastin time; Cmax; Maximum plasma concentration; FEIBA; Factor VIII inhibitor bypass activity; FEU; Fibrinogen equivalent units; FX; Factor X; FXa; Factor Xa; LMWH; Low-molecular-weight heparin; NOACs; Novel oral anticoagul

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Liquid chromatography-tandem mass spectrometric assay for the cyclin-dependent kinase inhibitor AT7519 in mouse plasma

Keywords: AUC0−∞; area under the plasma concentration-time curve; CDK; cyclin-dependent kinase; Cmax; maximum plasma concentration; EDTA; ethylenediaminetetraacetic acid; i.p.; intraperitoneal; IS; internal standard; MYCN; V-myc myelocytomatosis viral related

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه