دانلود مقالات ISI درباره Cmax + ترجمه فارسی

Pharmacokinetics of oral vitamin D3 and calcifediol

Keywords: AUC; area under the concentration vs time curve; Cmax; maximum concentration; Clast; concentration quantified before the next study drug intake; GMR; geometric mean ratio; HPLC; high performance liquid chromatography; tmax; time to reach Cmax; RCT; random

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Simplified LC-MS/MS method enabling the determination of azithromycin in human plasma after a low 100 mg dose administration

Keywords: AZI; azithromycin; Cmax; maximum plasma concentration; D-AZI; descladinose azithromycin; IS; internal standard; LLE; liquid-liquid extraction; m/z; mass/charge ratio; n; number of observations; Azithromycin; Liquid chromatography/tandem mass spectrometr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The relationship between in vivo antiviral activity and pharmacokinetic parameters of peramivir in influenza virus infection model in mice

Keywords: PK; pharmacokinetic; IV; intravenous; PD; pharmacodynamic; AUC; area under the concentration-time curve; Cmax; maximum concentration; IC50; 50% inhibitory concentration; IC95; 95% inhibitory concentration; T>IC95; time that drug concentration exceeds IC

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The influence of body size on the pharmacodynamic and pharmacokinetic response to clopidogrel and prasugrel: A retrospective analysis of the FEATHER study

Keywords: ACS; acute coronary syndrome; ADP; adenosine diphosphate; AM; active metabolite; AUC; area under the concentration-time curve; BMI; body mass index; BSA; body surface area; BW; body weight; CAD; coronary artery disease; Clop; clopidogrel; Cmax; maximum co

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Regular ArticleThe kidneys play an important role in the clearance of rFVIIa in rats

Keywords: AT; anti-thrombin; BSA; bovine serum albumin; C0; concentration at time 0 after iv administration; CL; clearance; CLNR; non-renal clearance; CLR; renal clearance; CMax; maximum concentration measured; EDTA; Ethylenediaminetetraacetic acid; ELISA; enzyme-l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

AXT914 a novel, orally-active parathyroid hormone-releasing drug in two early studies of healthy volunteers and postmenopausal women

Keywords: AE; adverse event; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUCtau; area under the time versus blood level curve in one dosing interval; BMD; bone mineral density; CaSR; calcium-sensing receptor; Cmax; maximum (peak) concentration;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Non-clinical pharmacokinetics and pharmacodynamics of rVIII-SingleChain, a novel recombinant single-chain factor VIII

Keywords: AUC; area under the observed average plasma concentration vs. time curve; AUC0-last; AUC up to the last quantifiable sampling time; CI; confidence interval; CL; clearance; Cmax; maximum plasma concentration; ELISA; enzyme-linked immunosorbent assay; FL; f

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Target-mediated clearance and bio-distribution of a monoclonal antibody against the Kunitz-type protease inhibitor 2 domain of Tissue Factor Pathway Inhibitor

Keywords: AUC; area under the curve; Cl; clearance; DAB; 3,3′-diaminobenzidine; dIF; double immunofluorescence; EGFR; epidermal growth factor receptor; GAG; glycosaminoglycans; GPI; glycosylphosphatidylinositol; FVIII; Factor VIII; FIX; Factor IX; FXa; Factor Xa;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Influence of the physiological variability of fasted gastric pH and tablet retention time on the variability of in vitro dissolution and simulated plasma profiles

Keywords: BCS; biopharmaceutics classification system; Cmax; maximum plasma concentration; GI; gastrointestinal; IIV; interindividual variability; IOV; interoccasion variability; MMC; migrating motoric complex; RSD; relative standard deviation; Gastric pH variabili

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory activity of sesaminol and sesaminol triglycoside on cytochrome P450 enzymes and their pharmacokinetics in rats

Keywords: STG; sesaminol triglycoside; CYPs; cytochrome P450; Cmax; the maximum plasma concentration; Tmax; the time to reach maximum plasma concentration; t1/2; the half-lives; AUC; the area under the drug concentration-time curve; Cl; clearance; Vd; volume of d

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Bioanalytical method for evaluating the pharmacokinetics of the GCP-II inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA)

Keywords: GCP-II; glutamate carboxypeptidase-II; PSMA; prostate specific membrane antigen; NAALADase; N-acetylated-alpha-linked acidic dipeptidase; NAAG; N-acetyl-aspartyl glutamate; 2-PMPA; 2-phosphonomethyl pentanedioic acid; 2-PMSA; 2-phosphonomethyl succinic ac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A study of Semen Strychni-induced renal injury and herb-herb interaction of Radix Glycyrrhizae extract and/or Rhizoma Ligustici extract on the comparative toxicokinetics of strychnine and brucine in rats

Keywords: AUC; area under concentration-time curve; Cmax; maximum plasma concentration; CYP450; cytochrome P450; P-gp; P-glycoprotein; CMC-Na; sodium carboxymethylcellulose; IS; internal standard; RG; Radix Glycyrrhizae; RL; Rhizoma Ligustici; GL; Radix Glycyrrhi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Reversal of New, Factor-specific Oral Anticoagulants by rFVIIa, Prothrombin Complex Concentrate and Activated Prothrombin Complex Concentrate: A Review of Animal and Human Studies

Keywords: AF; atrial fibrillation; aPCC; activated prothrombin complex concentrates; BID; twice daily; Cmax; maximal plasma concentration; F; coagulation factor; FEIBA; factor eight inhibitor bypass activity; PCC; prothrombin complex concentrates; rFVIIa; activated

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The effects of Glycyrrhizae uralenis and its major bioactive components on pharmacokinetics of daphnetin in Cortex daphnes in rats

Keywords: CD; Cortex daphnes; GU; Glycyrrhizae uralenis; CD-GU; combination of CD and GU; TCHM; traditional Chinese herbal medicine; CYP; cytochrome; UGT; UDP-glucuronosyltransferase; Cmax; peak plasma concentration; Tmax; time to Cmax; AUC0-t; area under the c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

A UPLC-MS/MS method for in vivo and in vitro pharmacokinetic studies of psoralenoside, isopsoralenoside, psoralen and isopsoralen from Psoralea corylifolia extract

Keywords: P; psoralen; IP; isopsoralen; PO; psoralenoside; IPO; isopsoralenoside; UPLC-MS/MS; ultra performance liquid chromatography tandem mass spectrometry; PCE; Psoralea corylifolia extract; PBGF; purified benzofuran glycosides fraction; TCM; traditional Chin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacokinetics and Antitumor Efficacy of Chemoembolization Using 40 µm Irinotecan-Loaded Microspheres in a Rabbit Liver Tumor Model

Keywords: ALP; alkaline phosphatase; AST; aspartate aminotransferase; AUC; area under the curve; Cmax; maximum concentration; CRLM; colorectal liver metastases; DE; drug-eluting; TANDEM-IRI; irinotecan-loaded drug-eluting microspheres (Embozene TANDEM Microspheres)

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacokinetic characterization of mangosteen (Garcinia mangostana) fruit extract standardized to α-mangostin in C57BL/6 mice

Keywords: ACN; acetonitrile; AUC; area under the curve; AUCinf; area under the curve from 0 to infinity; AUClast; area under the curve from 0 to 24 hours; Cmax; maximal concentration; LC-MS/MS; liquid chromatography-tandem mass spectrometry; MFE; mangosteen fruit

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition

Keywords: CYP; cytochrome P450; UGT; UDP-glucuronosyltransferase; S-Rg3; 20(S)-ginsenoside Rg3; R-Rg3; 20(R)-ginsenoside Rg3; S-Rh2; 20(S)-ginsenoside Rh2; R-Rh2; 20(R)-ginsenoside Rh2; NADP+; β-nicotinamide adenine dinucleotide phosphate; LC-MS/MS; liquid chrom

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Reversal of rivaroxaban-induced anticoagulation with prothrombin complex concentrate, activated prothrombin complex concentrate and recombinant activated factor VII in vitro

Keywords: ACCP; American College of Chest Physicians; ANOVA; analysis of variance; aPCC; activated prothrombin complex concentrate; CAT; calibrated automated thrombogram; Cmax; maximum concentration (of thrombin); CT; clotting time; DMSO; dimethyl sulphoxide; ETP;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Lack of Efficacy of an Inhibitor of PDE4 in Phase 1 and 2 Trials of Patients With Nonalcoholic Steatohepatitis

Keywords: Fatty Liver Disease; Therapeutic Targets; Treatment; PDE4; AE; adverse event; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under the plasma drug concentration time curve; AUCtau; area under the plasma drug concentration time c

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Médicaments et grossesse : modifications pharmacocinétiques et place du suivi thérapeutique pharmacologique

Keywords: grossesse; pharmacocinétique; suivi thérapeutique des médicaments; réponse thérapeutique tératogène; pregnancy; pharmacokinetics; therapeutic drug monitoring; treatment outcome; teratogen; Cmax; concentration plasmatique maximale; CYP; cytochrome P

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Original ResearchFull Report: Clinical-LiverTelaprevir Twice Daily Is Noninferior to Telaprevir Every 8 Hours for Patients With Chronic Hepatitis C

Keywords: OPTIMIZE; Clinical Trial; Protease Inhibitor; DAA; AE; adverse event; AUC24,ss; area under the plasma concentration-time curve from time of administration up to 24 hours; CI; confidence interval; Cmax; maximum concentration; Cmax,ss; maximum steady-state

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Frontiers in Liver TransplantationDrug-drug interactions with oral anti-HCV agents and idiosyncratic hepatotoxicity in the liver transplant setting

Keywords: ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; AUC; Area under the curve; BOC; Boceprevir; BSEP; Bile salt export pump; Cmax; Maximum concentration; CNI; Calcineurin inhibitors; CYP; Cytochrome P450; DAA; Direct acting antivirals; DDI; Dr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacokinetic interactions between topiramate and pioglitazone and metformin

Keywords: ANOVA; analysis of variance; AUC12; area under concentration-time curve over dosing interval of 12 h; AUC24; area under concentration-time curve over dosing interval of 24 h; BID; twice daily dosing; CI; confidence interval; CL/F; oral clearance; Cm

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Intramuscular Administration of Paliperidone Palmitate Extended-Release Injectable Microsuspension Induces a Subclinical Inflammatory Reaction Modulating the Pharmacokinetics in Rats

Keywords: prodrugs; nanoparticles; muscle; disposition; biocompatibility; pharmacokinetics; paliperidone palmitate; sustained release; histopathology; inflammation; API; active pharmaceutical ingredient; AUC; area under the (plasma concentration vs. time) curve; CL

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

The effects of wine-processing on ascending and descending: The distribution of flavonoids in rat tissues after oral administration of crude and wine-processed Radix scutellariae

Keywords: TCM; Traditional Chinese Medicine; LLOQ; lower limits of quantification; QC; quality control; DP; declustering potential; CE; collision energy; CXP; collision exit potential; RE; relative error; FDA; Food and Drug Administration; t1/2; the half-time; Cmax

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Grupo de Trabajo Conjunto sobre cirugía no cardiaca: Evaluación y manejo cardiovascular de la Sociedad Europea de Cardiología (ESC) y la European Society of Anesthesiology (ESA)

Keywords: Guías de Práctica Clínica; Cirugía no cardiaca; Evaluación preoperatoria del riesgo cardiaco; Pruebas cardiacas preoperatorias; Revascularización arterial coronaria preoperatoria; Manejo cardiaco perioperatorio; Tratamiento antitrombótico; Bloquead

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2014 سفارش ترجمه

Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

Keywords: α-ZAL; α-zearalanol; α-ZEL; α-zearalenol; β-ZAL; β-zearalanol; β-ZEL; β-zearalenol; ACN; acetonitrile; AUC; area under the plasma concentration-time curve; BW; body weight; Cl; clearance; Cmax; maximum plasma concentration; DON; deoxynivalenol;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleAntiviral activity of boceprevir monotherapy in treatment-naive subjects with chronic hepatitis C genotype 2/3

Keywords: AE; adverse event; ANOVA; analysis of variance; AUC; area under the plasma concentration-time curve; BMI; body mass index; Cmax; maximum observed plasma concentration; CHC; chronic hepatitis C; CLss/F; apparent total body clearance at steady state; DAA; d

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

An in vitro investigation of the cardiovascular effects of the 5-HT4 receptor selective agonists, velusetrag and TD-8954

Keywords: 5-HT; 5-hydroxytryptamine or serotonin; ADP; adenosine diphosphate; cDNA; complementary deoxyribonucleic acid; CHO-K1; Chinese hamster ovary K1; C-IBS; constipation predominant irritable bowel syndrome; CIC; chronic idiopathic constipation; Cmax; maximum

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Increased volume of distribution for recombinant activated factor VII and longer plasma-derived factor VII half-life may explain their long lasting prophylactic effect

Keywords: pdFVII; Plasma-derived factor VII; rFVIIa; Recombinant activated factor VII; FVII; Factor VII; NCA; Non-Compartmental Analysis; OCA; One-Compartmental Analysis; Hb; Hemoglobin; T½; Half-life; Cmax; Peak plasma concentration of a drug after administration

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibitory effects of astaxanthin, β-cryptoxanthin, canthaxanthin, lutein, and zeaxanthin on cytochrome P450 enzyme activities

Keywords: CYP; cytochrome P450; AS; astaxanthin; βC; β-cryptoxanthin; CA; canthaxanthin; LU; lutein; ZE; zeaxanthin; NADP+; β-nicotinamide adenine dinucleotide phosphate; LC-MS/MS; liquid chromatography-tandem mass spectrometry; Cmax; maximum plasma concentr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: Examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia

Keywords: 5-HT2; 5-hydroxytryptamine; 6-OHDA; 6-hydroxydopamine; AM; allosteric modulator; AUC; area under curve; AUCINF; area under curve extrapolated to infinity; AUClast; area under curve from dosing to observation; AUMC; area under first moment curve; CL; total

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387

Keywords: AUC; area under the plasma concentration-time curve; Cmax; maximum drug concentration in plasma; Tmax; the time after administration of a drug when the maximum plasma concentration is reached; BBB; blood-brain barrier; BCRP; breast cancer resistance p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Concentration-dependent inhibitory effects of baicalin on the metabolism of dextromethorphan, a dual probe of CYP2D and CYP3A, in rats

Keywords: S. baicalensis; Scutellaria baicalensis; CYP; cytochrome P450; CYP2D; cytochrome P450 2D; CYP3A; cytochrome P450 3A; DXM; dextromethorphan; BG; baicalin; RLMs; rat liver microsomes; Km; substrate concentration at half-maximal product formation rate; Ki; i

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Hemolytic and pharmacokinetic studies of liposomal and particulate amphotericin B formulations

Keywords: AmB; Amphotericin B; RBCs; red blood cells; RES; reticulo-endothelial system; FD; non-microencapsulated free dimeric AmB formulation; F; Fungizone®; HF; heated-Fungizone; MD; microencapsulated dimer AmB; FP; non-microencapsulated free poly-aggregated AmB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacokinetics, pharmacodynamics and toxicity of a combination of metoprolol succinate and telmisartan in Wistar albino rats: Safety profiling

Keywords: LC-MS/MS; Liquid Chromatography-Mass Spectroscopy/Mass Spectroscopy; MET; metoprolol succinate; TEL; telmisartan; IS; Internal Standard; CPCSEA; Committee for the Purpose of Control and Supervision of Experiments on Animals; IAEC; Institutional Animal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: New set of data for predictive in silico ADME models

Keywords: ADME; absorption distribution metabolism and excretion; AEDs; antiepileptic drugs; AUC; area under the plasma drug concentration-time curve; BBB; blood-brain barrier; CBZ; carbamazepine; CBZ-E; carbamazepine-10,11-epoxide; Cmax; maximum peak concentra

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacokinetic study of salvianolic acid A in beagle dog after oral administration by a liquid chromatography-mass spectrometry method: A study on bioavailability and dose proportionality

Keywords: SAA; salvianolic acid A; IS; internal standard; CH3CN; acetonitrile; MeOH; methanol; HCOOH; formic acid; HCl; hydrochloric acid; EtOAc; ethyl acetate; VC; vitamin C; HPLC; high performance liquid chromatography; LC/MS/MS; liquid chromatography/tandem mass

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

Transarterial Sorafenib Chemoembolization: Preliminary Study of Technical Feasibility in a Rabbit Model

Keywords: Cmax; peak plasma concentration; HCC; hepatocellular carcinoma; HIF; hypoxia-inducible factor; LC-MS/MS; liquid chromatography/tandem mass spectrometry; SRM; selected reaction monitoring; UHPLC; ultra-high-pressure liquid chromatography; VEGF; vascular

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacokinetics of Intravesical Versus Oral Oxybutynin in Healthy Adults: Results of an Open Label, Randomized, Prospective Clinical Study

Keywords: urinary bladder; oxybutynin; desethyloxybutynin; pharmacokinetics; adverse effects; ADR; adverse drug reaction; AE; adverse effect/event; AUC; area under plasma concentration time curve; AUC∞; AUC extrapolated to infinity; Cmax; peak plasma concentratio

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Internal Mammary Artery Harvesting Influences Antibiotic Penetration Into Presternal Tissue

Keywords: ACT; time of aortic cross clamp; AUC; area under the concentration curve; BMI; body mass index; BUN; blood urea nitrogen; CABG; coronary artery bypass grafting; Cmax; maximum drug concentration; CO; cardiac output; CPB; cardiopulmonary bypass; DSWI; deep

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Anti-inflammatory effects of sophocarpine in LPS-induced RAW 264.7 cells via NF-κB and MAPKs signaling pathways

Keywords: Cmax; maximum plasma concentration; COX-2; cyclooxygenase-2; Erk1/2; extracellular signal-regulated kinase 1/2; IκB; inhibitor κB; IL-6; interleukin-6; iNOS; inducible nitric oxide synthase; JNK; c-Jun NH2-terminal kinase; LDH; lactate dehydrogenase; LP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacokinetics and tissue distribution of resveratrol, emodin and their metabolites after intake of Polygonum cuspidatum in rats

Keywords: PC; Polygonum cuspidatum; S/G; sulfates/glucuronides; LLOQ; lower limit of quantitation; LOD; limit of detection; Cmax; the peak plasma concentration; tmax; the time to peak concentration; AUC0-t; the areas under the plasma concentration-time curves; MR

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Improved dissolution and pharmacokinetic behavior of dipyridamole formulation with microenvironmental pH-modifier under hypochlorhydria

Keywords: ANOVA; analysis of variance; AUC; area under the curve of blood concentration vs. time; BA; bioavailability; Cmax; maximum concentration; CV; coefficient of variation; DP; dipyridamole; DPG; granule formulation of dipyridamole; FA; fumaric acid; HCl; hydr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Inductive modulation on P-glycoprotein and cytochrome 3A by resveratrol, a constituent of grapes

Keywords: CsA; cyclosporine; P-gp; P-glycoprotein; CYP3A4; cytochrome P450 3A4; RDS; resveratrol dietary supplement; HPLC; high-performance liquid chromatography; Cmax; the peak blood concentration; AUC0-t; the areas under the curves from time zero to last; MRT;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Liquorice reduced cyclosporine bioavailability by activating P-glycoprotein and CYP 3A

Keywords: AUC0-t; the areas under the curves from time zero to last; Cmax; the peak blood concentration; CsA; cyclosporine; CYP3A4; cytochrome P450 3A4; GA; glycyrrhetic acid; GZ; glycyrrhizin; LE; liquorice extract; MRT; mean residence time; P-gp; P-glycoprotein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein

Keywords: AUC0-6 h; Area under the plasma concentration time curve from 0 to 6 h; B/P; Brain/Plasma; BSA; Bovine serum albumin; Cmax; Maximum drug concentration; CNS; Central nervous system; DDI; Drug-drug interaction; EPS; Extrapyramidal symptoms; FBS; Fetal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Novel formulations of dipyridamole with microenvironmental pH-modifiers for improved dissolution and bioavailability under hypochlorhydria

Keywords: ANOVA; analysis of variance; API; active pharmaceutical ingredient; AA; adipic acid; D; l-aspartic acid; AUC; area under the curve of plasma concentration vs. time; BCS; biopharmaceutics classification system; CA; citric acid monohydrate; Cmax; maximum co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11)

Keywords: ACN; anthocyanin; BCRP; breast cancer resistance protein; Cmax; maximum plasma concentration; CHO; Chinese hamster ovary; DDI; drug-drug interaction; ES; estrone sulfate; fu; fraction unbound in plasma; FDA; Food and Drug Administration; HEK; human embr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه