Keywords: dsDNA; double-stranded DNA; MIF; macrophage migration inhibitory factor; Ang-2; angiopoietin 2; CENPF; centromere protein F; Her2/neu; human epidermal growth factor receptor 2; MUC1; mucin 1; IMP2; insulin-like growth factor mRNA-binding family member 2;
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Keywords: BM; brain metastasis; AE; adverse event; CI; confidence interval; CTLA4; cytotoxic T-lymphocyte antigen-4; CT; computed-tomography; GPA; Graded Prognostic Assessment score; IORR; intracerebral objective response rate; IQR; interquartile range; NSCLC; nonâ
Keywords: 5â²AMP; 5â² adenosine monophosphate; ADO; adenosine; DSAs; anti-donor specific antibodies; APC; antigen-presenting cell; CXCL-9; chemokine (C-X-C motif) ligand 9; cAMP; cyclic adenosine monophosphate; CTLA4; cytotoxic T-lymphocyte associated protein 4;
Keywords: APC; antigen presenting cell; APOBEC; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like; BRCA1/2; breast cancer 1/2; BCSS; breast cancer specific survival; B2M; β-2-microglobulin; CAF; cancer associated fibroblast; CCL; chemokine ligand; CD
Keywords: Flow cytometry; Intracellular protein; Monoclonal antibody; Primary immunodeficiency disease; Surface protein; ADA; adenosine deaminase; ALPS; autoimmune lymphoproliferative syndrome; APECED; autoimmune polyendocrinopathy-candidiasis-ectodermal dystrop
Keywords: 5-FU; 5-fluorouracil; AF; atrial fibrillation; ALK; anaplastic lymphoma kinase; APD; action potential duration; APL; acute promyelocytic leukemia; BCR-ABL; breakpoint cluster region-Abelson; BTK; Bruton tyrosine kinase; CD20; cluster of differentiation 20
Keywords: Brain; Metastasis; Immunotherapy; CTLA4; PD1/PDL1; Biomarkers;
Keywords: Primary immunodeficiency; malignancy; tumor predisposition; immune surveillance; pre-existing condition; ALL; Acute lymphoblastic leukemia; ALPS; Autoimmune lymphoproliferative syndrome; AT; Ataxia teleangiectasia; CHH; Cartilage-hair hypoplasia; CID; Com
Keywords: AP-1; activating protein 1; APC; antigen presenting cell; CAR; chimeric antigen receptors; Cbl-b; casitas B-lineage lymphoma; DAG; diacylglycerol; cSMAC; central supramolecular activation cluster; CTLA4; cytotoxic T lymphocyte antigen 4; dSMAC; distal sup
Keywords: ADA; antidrug antibody; ALI/ARDS; acute lung injury/acute respiratory distress syndromes; Ab; antibody; ADC; antibody drug conjugate; ADCC; antigen-dependent cellular cytotoxicity; BAL; bronchoalveolar lavage; BsAbs; bispecific antibodies; CCL; CC chemoki
Keywords: Tumor immunology; Immunotherapy; T cells; CTLA4; PD-1;
Keywords: Personalized medicine; primary immunodeficiency disorders; immune dysregulation; autoimmunity; therapy; mutation; APDS; Activated phosphoinositide 3-kinase syndrome; CMC; Chronic mucocutaneous candidiasis; CTLA4; Cytotoxic lymphocyte antigen 4; GOF; Gain
Keywords: Immune checkpoint inhibitors; Therapeutic monoclonal antibodies; CTLA4; PD-1 - PDL-1 axis; Immune-related adverse events;
Keywords: MTX; methotrexate; TNF; tumor necrosis factor; IL; interleukin; CTLA4; cytotoxic T-lymphocyte antigen 4; IFX; infliximab; ADA; adalimumab; GLM; golimumab; CZP; certolizumab pegol; ETN; etanercept; TCZ; tocilizumab; ABA; abatacept; RTX; rituximab; UTK; ust
Keywords: IC; immune checkpoint; ICB; immune checkpoint blocker; irAE; immune-related adverse event; NSCLC; non-small cell lung cancer; ORR; overall response rate; OS; overall survival; RCC; renal cell carcinoma; Neoplasms; Aged; Toxicity; Immunotherapy; Medical on
Keywords: ARCON; accelerated radiotherapy with carbogen and nicotinamide; cAMP; cyclic adenosine monophosphate; CA4P; combretastatin A-4 phosphate; CAIX; carbonic anhydrase IX; CNS; central nervous system; CT; computed tomography; CTLA4; cytotoxic T-lymphocyte asso
Keywords: Autoimmunity; primary immunodeficiency diseases; BÂ cells; T cells; AID; Activation-induced cytidine deaminase; AIHA; Autoimmune hemolytic anemia; AIRE; Autoimmune regulator; ALPS; Autoimmune lymphoproliferative disease; ANA; Anti-nuclear autoantibody; AP
Keywords: Ago2; argonaute 2; CDE; clathrin-dependent endocytosis; CIE; clathrin-independent endocytosis; CPP; cell penetrating peptides; CTLA4; cytotoxic T-lymphocyte-associated antigen 4; ECM; extracellular matrix; EPR; enhanced permeability and retention; ERC; en
Keywords: Atopic dermatitis; laser capture microdissection; IL-34; claudins 8 and 4; immune; barrier; AD; Atopic dermatitis; CE; Cornified envelope; CLDN; Claudin; CSF-1R; Colony-stimulating factor 1 receptor; CTLA4; Cytotoxic T-lymphocyte antigen 4; DC; Dendritic
Keywords: TAAs; Tumor-associated antigens; MUC1; Mucin 1; HER2/neu; Human epidermal growth factor receptor 2; CEA; Carcinoembryonic antigen; HLA; Human leukocyte antigen; TSA; Tumor-specific antigen; TAP; Transporter associated with antigen processing; ER; Endoplas
Keywords: CRH; corticotropin-releasing hormone; CTLA4; cytotoxic T lymphocyte antigen 4; IFN-γ; interferon gamma; DC; dendritic cell; E2; estradiol-17β; ER; estrogen receptor; hCG; human chronic gonadotropin; HPA; hypothalamic-pituitary-adrenal; NF-κB; nuclear f
Keywords: Co-stimulatory molecules; CD40 ligand; CD40; CTLA4; CTLA4Ig; Abatacept;
Generating the Abscopal Effect by Combining Proapoptotic Peptides With IL-12-Based Immunotherapy
Keywords: CTLA4; Cytotoxic T lymphocyte-associated antigen 4; DCs; Dendritic cells; IL-12; Interleukine-12; MDSCs; Myeloid-derived suppressor cells; NK cells; Natural killer cells; PAPs; Proapoptotic peptides; PD1; Programmed cell death protein 1; Tregs; Regulatory
Human Leukocyte Antigen class II polymorphisms among Croatian patients with type 1 diabetes and autoimmune polyglandular syndrome type 3 variant
Keywords: AITD; autoimmune thyroid disease; APS3v; autoimmune polyglandular syndrome type 3 variant; AT; autoimmune thyroiditis; CTLA4; cytotoxic T lymphocyte antigen 4; ELISA; enzyme immunoassay; FOXP3; forehead box P3; GAD; glutamic acid decarboxylase; GD; Graves
Association of the 16q24.3 region gene variants rs1805007 and rs4785763 with heightened risk of melanoma in Latvian population
Keywords: ACD; adrenocortical dysplasia protein homolog gene; AFG3L1P; AFG3-like matrix AAA peptidase subunit 1 of the pseudogene; BAP1; BRCA1 associated protein-1 gene; BRAF; serine/threonine-protein kinase B-Raf; CDK4; cyclin-dependent kinase 4; CDK10; cyclin-dep
The expression of mCTLA-4 in skin lesion inversely correlates with the severity of psoriasis
Keywords: CTLA4; Cytotoxic T lymphocyte antigen-4; sCTLA-4; soluble Cytotoxic T lymphocyte antigen-4; mCTLA-4; membrane Cytotoxic T lymphocyte antigen-4; IOD; Integrated option density; IMQ; Imiquimod; PASI; psoriasis area and severity index; Treg; regulatory T; CT
Concern over cost of and access to cancer treatments: A meta-narrative review of nivolumab and pembrolizumab studies
Keywords: ASCO; American Society of Clinical Oncology; BRAF; B-raf proto-oncogene, serine/threonine kinase; CTLA4; cytotoxic T-lymphocyte associated protein 4; ESMO; European Society for Medical Oncology; FDA; Food and Drug Administration; ICER; incremental cost-ef
miR-487a-3p upregulated in type 1 diabetes targets CTLA4 and FOXO3
Keywords: T1D; Microarray; Expression; miR-487a-3p; CTLA4; FOXO3;
Vitamin D3 inhibits the proliferation of T helper cells, downregulate CD4+ T cell cytokines and upregulate inhibitory markers
Keywords: Cytokine; T cell; Vitamin D3; PD1; CTLA4;
Predictive markers of anti-VEGF and emerging role of angiogenesis inhibitors as immunotherapeutics
Keywords: Angiogenesis; Immunotherapy; VEGF; CTLA4; PD-L1/PD-1; Predictive biomarkers; Clinical trials; Cancer immunity; Inflammation;
FOXOs in cancer immunity: Knowns and unknowns
Keywords: 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot
Correlation between messenger RNA expression and protein expression of immune checkpoint-associated molecules in bladder urothelial carcinoma: A retrospective study
Keywords: Bladder cancer; Molecular marker; RT-PCR; Immunohistochemistry; Immune checkpoints; PD-1; CTLA4;
Polymerase proofreading domain mutations: New opportunities for immunotherapy in hypermutated colorectal cancer beyond MMR deficiency
Keywords: CRC; colorectal cancer; mCRC; metastatic CRC; CTLA4; cytotoxic T-lymphocyte-associated antigen 4; EGFR; epithelial growth factor receptor; HR; hazard ratio; MAP; mitogen-activated protein; mAb; monoclonal antibody; MEK; mitogen-activated protein/extracell
Evaluation of peripheral blood T lymphocyte surface activation markers and transcription factors in patients with early stage non-small cell lung cancer
Keywords: NSCLC; T-cells; Transcription factors; Lung cancer; Checkpoint antigens; PD-1; CTLA4;
Hematologic neoplasms: Dendritic cells vaccines in motion
Keywords: DCs; dendritic cells; TAA; tumor-associated antigens; APC; antigen presenting cells; mDCs; myeloid dendritic cells; pDCs; plasmacytoid dendritic cells; HLA; human leukocyte antigen; Ag Antigens; abs antibodies; PBMCs; peripheral blood mononuclear cells; G
Analysis of non-small cell lung cancer microenvironment indicates preponderance of T cell exhaustion marker expression
Keywords: CTLA4; cytotoxic T-lymphocyte-associated protein 4; LAG3; lymphocyte activated gene 3; PD-1; programmed cell death protein 1; CFSE; carboxyfluorescein succinimidyl ester; CD25 neg; CD25Dep cells; Lung cancer; Microenvironment; T cell; Exhaustion marker;
Modulation of cytotoxic responses by targeting CD160 prolongs skin graft survival across major histocompatibility class I barrier
Keywords: HVEM; herpesvirus entry mediator; BTLA; B- and T-lymphocyte attenuator; CTLA4; cytotoxic T-lymphocyte antigen; CD; cluster of differentiation; CRD; cysteine-rich domain; mHVEM.Ig; mouse HVEM extracellular domain bound to mouse IgG2a Fc fragment; mCD160.Ig
Management of Muscle-Invasive Urothelial Cancer and the Emerging Role of Immunotherapy in Advanced Urothelial Cancer
Keywords: AKT; AKT serine/threonine kinase 1; BCG; bacillus Calmette-Guérin; CTLA4; cytotoxic T-lymphocyte-associated protein 4; EGFR; epidermal growth factor receptor; FDA; Food and Drug Administration; FGFR; fibroblast growth factor receptor; GC; gemcitabine p
Development of novel avenues to overcome challenges facing CAR T cells
Keywords: AICD; activation-induced cell death; AMP; adenosine monophosphate; APC; antigen-presenting cells; ATP; adenosine triphosphate; CAFs; cancer-associated fibroblasts; CAR; chimeric antigen receptor; CEA; carcinoembryonic antigen; CTLA4; cytotoxic T-lymphocyt
Thymus transplantation for complete DiGeorge syndrome: European experience
Keywords: DiGeorge syndrome; athymia; thymus transplantation; AIRE; Autoimmune regulator; ATG; Antithymocyte globulin; cDGS; Complete DiGeorge syndrome; CHARGE; Coloboma, heart defects, atresia choanae, retardation of growth and development, genital abnormalities,
Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells
Keywords: ASNS; asparagine synthetase; AXL; proto-oncogene tyrosine kinase receptor AXL; BRAF; B-Raf proto-oncogene serine/threonine kinase/v-raf murine sarcoma viral oncogene homolog B; CCL2; chemokine C-C motif ligand 2; CE; coexpression coefficient; CHAC1; ChaC
Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas
Keywords: Immunotherapy; GPC3; MAGEC2; Galectin 9; APC; antigen-presenting cells; BTLA; BÂ and T lymphocyte attenuator; CFSE; carboxyfluorescein diacetate succinimidyl ester; CTL; cytotoxic T cells; CTLA4; cytotoxic T-lymphocyte associated protein 4; GAL-9; galecti
Increased Expression of Cytotoxic T-LymphocyteâAssociated Protein 4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure
Keywords: Immune Regulation; Liver Disease; Treatment; Infection Susceptibility; AALF; acetaminophen-induced acute liver failure; ALF; acute liver failure; APAP; acetaminophen; CLD; chronic liver disease; CTLA4; cytotoxic T-lymphocyteâassociated molecule-4; DC; d
Interleukin (IL)-24 transforms the tumor microenvironment and induces anticancer immunity in a murine model of colon cancer
Keywords: IL-24; interleukin-24; PBMCs; peripheral blood mononuclear cells; MDA; melanoma differentiation-associated gene; IFN-γ; interferon-α; CTLA4; cytotoxic T-lymphocyte-associated protein 4; PD1; programmed cell death 1; TILs; tumor infiltrating lymphocytes;
Immune signature of urothelial cancer associated with grade, recurrence, and invasion
Keywords: Urothelial cancer; Cytokines; NFκB; CTLA4;
CRAC channels, calcium, and cancer in light of the driver and passenger concept
Keywords: CRAC channels; Calcium; STIM; STIM1; STIM2; Orai; Orai1; Orai2; Orai3; TRPV5; TRPV6; Cancer; Tumor; Cancer driver gene; Cancer passenger gene; CTLA4; Checkpoint therapy; Cytotoxic T lymphocytes (CTL); Natural killer (NK) cells; Tumor microenvironment;
Surfactant protein D induces immune quiescence and apoptosis of mitogen-activated peripheral blood mononuclear cells
Keywords: Surfactant protein D; PBMC; Lymphocytes; Monocytes; Inflammation; CTLA4
Association of functional genetic variants of CTLA4 with reduced serum CTLA4 protein levels and increased risk of idiopathic recurrent miscarriages
Keywords: CTLA4; haplotype; linkage disequilibrium; polymorphisms; recurrent miscarriage;
Immune deficiencies, infection, and systemic immune disordersIL-2 consumption by highly activated CD8 TÂ cells induces regulatory T-cell dysfunction in patients with hemophagocytic lymphohistiocytosis
Keywords: Regulatory T cells; familial hemophagocytic lymphohistiocytosis; IL-2; immune homeostasis; perforin; lymphocytic choriomeningitis virus; CTLA4; Cytotoxic T lymphocyte-associated antigen 4; FHL; Familial hemophagocytic lymphohistiocytosis; Foxp3; Forkhea
The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes
Keywords: CTLA4; cytotoxic T-lymphocyte-associated protein 4; DEG; differentially expressed gene; FDR; false discovery rate; GSVA; gene set variation analysis; K16; keratin 16; PASI; Psoriasis Area and Severity Index; TH; T helper; Treg; regulator T cell;