Keywords: سیکلین وابسته به کیناز 2; ACE; angiotensin converting enzyme; AO; acridine orange; BAD; Bcl-2-associated death promoter; BAX; BCL2-associated X protein; B cells; B lymphocytes; Bcl-2; B-cell lymphoma 2; CCL18; chemokine (CC motif) ligand 18; CD; cluster of differentiation; CDK2; c
مقالات ISI سیکلین وابسته به کیناز 2 (ترجمه نشده)
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Keywords: سیکلین وابسته به کیناز 2; 4- Shogaol (PubChem CID: 9794897); 6- Shogaol (PubChem CID: 5281794); Apigenin (PubChem CID: 5280443); Berberine (PubChem CID: 2353); Bergamottin (PubChem CID: 5471349); Caffeic acid (PubChem CID: 689043)Capsaicin (PubChem CID: 1548943); Cardamonin (PubCh
Keywords: سیکلین وابسته به کیناز 2; 17β-HSD; 17-beta hydroxysteroid dehydrogenase; MLHI; MutL Ecoli homolog 1; 2,5-HD; 2,5-n-hexandione; MMPs; Matrix metalloproteinases; AHr; Aryl Hydrocarbon receptor; MRP1; Multi-drug Resistance protein 1; Akr1c; Aldo-keto reductase family; NF-κβ; Nucle
Keywords: سیکلین وابسته به کیناز 2; Endothelial cell senescence; Genetic; Vascular ageing; Age-related diseases; Stem cell; Ang II; angiotensin II; APOE; apolipoprotein E; AQP1; aquaporin 1; ASS1; argininosuccinate synthase 1; CDK2; cyclin-dependent kinase 2; CDKN2A; cyclin-dependent kinase
Keywords: سیکلین وابسته به کیناز 2; ARG; arctigenin; GSH; glutathione; G0/G1; Gap 0/Gap 1; NPAT; nuclear protein of the ataxia telangiectasia locus; CDK2; cyclin-dependent kinase 2; CDK7; cyclin-dependent kinase 7; akt-1; alpha serine/threonine-protein kinase; Arctigenin (ARG); Mechanism; S
MicroRNA-143a-3p modulates preadipocyte proliferation and differentiation by targeting MAPK7
Keywords: سیکلین وابسته به کیناز 2; aP2; adipocytefatty acid-binding protein; p21; cyclin-dependent kinase inhibitor 1; CDK2; cyclin-dependent kinase 2; Cyclin B; cell cycle protein B; Cyclin E; cell cycle protein E; CDK3; cyclin-dependent kinases 3; CDK4; cyclin-dependent kinases 4; C/EBPÎ
Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair
Keywords: سیکلین وابسته به کیناز 2; CDK4/6; cyclin-dependent kinases 4 and 6; CDK2; cyclin-dependent kinase 2; iCDK4/6; inhibitor of CDK4/6; LEE011; inhibitor of CDK4/6, ribociclib, Kisqali; PD0332991; inhibitor of CDK4/6, palbociclib, Imbrance; NU6140; cyclin-dependent kinase 2 (CDK2) inhi
Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor
Keywords: سیکلین وابسته به کیناز 2; Nicotinic acetylcholine receptor; Ion channel; Allosteric modulation; Virtual screening; 5-HT; 5-hydroxytryptamine; DB04763; 1-N-(4-sulfamoylphenethyl)-2,4,6-trimethylpyridinium tetrafluoroborate; AUC; area under the curve; CAII; carbonic anhydrase II; CD
Progesterone arrested cell cycle progression through progesterone receptor isoform A in pancreatic neuroendocrine neoplasm
Keywords: سیکلین وابسته به کیناز 2; Pan-NEN; pancreatic neuroendocrine neoplasm; PR; progesterone receptor; PRA; PR isoform A; PRB; PR isoform B; CCNA2; cyclin A2; CCNB1; cyclin B1; CDK1; cyclin-dependent kinase 1; CDK2; cyclin-dependent kinase 2; WHO; World Health Organization; Neuroendocr
Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway
Keywords: سیکلین وابسته به کیناز 2; Advanced oxidation protein products; S-phase arrest; Reactive oxygen species; β-catenin; Cyclin-dependent kinase 2; Liver regeneration;
Bavachalcone from Cullen corylifolium induces apoptosis and autophagy in HepG2 cells
Keywords: سیکلین وابسته به کیناز 2; C. corylifolium; Bavachalcone; Apoptosis; Cell cycle; Autophagy; CCE; Cullen corylifolium ethanol extract; HCC; hepatocellular carcinoma; NAFLD; Nonalcoholic fatty liver disease; Bax; bcl-2-associated X protein; Bcl-2; b-cell lymphoma 2; Bid; BH3 interact
PM2.5-induced alterations of cell cycle associated gene expression in lung cancer cells and rat lung tissues
Keywords: سیکلین وابسته به کیناز 2; PM2.5; p53; p21; Cell division cycle 2; Cyclin-dependent kinase 2; Cyclin B;
MicroRNA-27a-3p affects estradiol and androgen imbalance by targeting Creb1 in the granulosa cells in mouse polycytic ovary syndrome model
Keywords: سیکلین وابسته به کیناز 2; miRNA; microRNA; miR-27-3p; microRNA-27a-3p; mGC; mouse granulosa cell; E2; estradiol; GC; granulosa cell; Creb1; cyclic AMP response element (CRE)-binding protein 1; Cyp19a1; cytochrome P450 family 19 subfamily A polypeptide 1; DHT; dihydrotestosterone;
PARP1 orchestrates epigenetic events setting up chromatin domains
Keywords: سیکلین وابسته به کیناز 2; ARH3; ADP-ribosyl hydrolase 3; ARTD; ADP-ribosyltransferases diphtheria toxin-like; BRCA1; breast cancer type 1 susceptibility protein; CBP; CREB-binding protein; CCDN1; cyclin-dependent kinase 2; CTCF; CCCTC-binding factor; DMR1; differentially methylate
Trisubstituted purine inhibitors of PDGFRα and their antileukemic activity in the human eosinophilic cell line EOL-1
Keywords: سیکلین وابسته به کیناز 2; PDGFRα; platelet derived growth factor receptor alpha; CDK2; cyclin-dependent kinase 2; TK; tyrosine kinase; MAPK; mitogen-activated protein kinase; STAT; signal transducers and activators of transcription;
G2/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph3PAu[SC(OR)Â =Â NPh], RÂ =Â Me, Et, and iPr, during zebrafish development
Keywords: سیکلین وابسته به کیناز 2; Annexin V-FITC; Recombinant annexin V conjugated to fluorescein isothiocyanate; APAF-1; Apoptotic protease activating factor 1; ATR; Ataxia telangiectasia and Rad3-related; Bax; Apoptosis regulator; Bcl-2; B-cell lymphoma 2; BIRC-5; Baculoviral inhibitor
Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines
Keywords: سیکلین وابسته به کیناز 2; Cyclin-dependent kinase 2; ATP-competitive type I inhibitors; Pyrazolo[1,5-a]pyrimidine; Quantum mechanical scoring; Protein-ligand binding; Molecular dynamics; Water thermodynamics; X-ray crystal structure;
Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal
Keywords: سیکلین وابسته به کیناز 2; CAR; constitutive androstane receptor; CDK2; cyclin-dependent kinase 2; ChIP assay; chromatin immunoprecipitation assay; CYP; cytochrome P450; FOXO1; forkhead box protein O1; PCK1; phosphoenolpyruvate carboxykinase 1; PPARα; peroxisome proliferator-activ
Novel miR-5582-5p functions as a tumor suppressor by inducing apoptosis and cell cycle arrest in cancer cells through direct targeting of GAB1, SHC1, and CDK2
Keywords: سیکلین وابسته به کیناز 2; CRC; colorectal cancer; miRNA; microRNA; MTS; (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium); GAB1; GRB2-associated binding protein 1; SHC1; SRC homology 2 domain containing 1; GRB2; growth factor receptor-bound
Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors
Keywords: سیکلین وابسته به کیناز 2; Cyclin-dependent kinase 2; Kinase inhibitors; Anti-tumor agent; 1H-pyrrolo[2,3-b]pyridine; [3Â +Â 2] cycloaddition; 1,4-Triazole; 1,5-Triazole; 3D-QSAR CoMFA; CCR2; CC chemokine receptor 2; CCL2; CC chemokine ligand 2; CCR5; CC chemokine receptor 5;
Discovery of novel indirubin-3′-monoxime derivatives as potent inhibitors against CDK2 and CDK9
Keywords: سیکلین وابسته به کیناز 2; Indirubin-3′-oxime derivatives; Cyclin-dependent kinase 2; Cyclin-dependent kinase 9; Structure–activity relationship
miR-200c-SUMOylated KLF4 feedback loop acts as a switch in transcriptional programs that control VSMC proliferation
Keywords: سیکلین وابسته به کیناز 2; ATRA; all-trans retinoic acid; cdk2; cyclin-dependent kinase 2; HASMC; human aortic smooth muscle cell; HDAC2; histone deacetylase 2; KLF; Krüppel-like factor; LSD1; lysine-specific demethylase 1; miR; microRNA; NCoR; nuclear receptor corepressor; p21; p
Activation of Src family tyrosine kinases by ferric ions
Keywords: سیکلین وابسته به کیناز 2; CCK; cholecystokinin; CDK2; cyclin-dependent kinase 2; DMEM; Dulbecco's Modified Eagle Medium; HBS; HEPES-buffered saline; SFK; Src-family tyrosine kinases; Calcium; Kinase; Ferric; Iron; Phosphotyrosine;
Myostatin knockout using zinc-finger nucleases promotes proliferation of ovine primary satellite cells in vitro
Keywords: سیکلین وابسته به کیناز 2; Satellite cells; Myostatin; Gene expression; Mutant; Proliferation; PSC; primary satellite cell; TGF-β; transforming growth factor β; CDK2; cyclin-dependent kinase 2; p21; cyclin-dependent kinase inhibitor 1; DMEM; Dulbecco's modified eagle medium; FBS;
Distinct functions of steroidogenic factor-1 (NR5A1) in the nucleus and the centrosome
Keywords: سیکلین وابسته به کیناز 2; CDK2; cyclin-dependent kinase 2; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; SF-1; Steroidogenic Factor 1 NR5A1, Ad4BP; SUMO; small ubiquitin like modifier; MT; microtubule; SF-1; Adrenal; Gonad; Centros
STAT1 requirement for PKR-induced cell cycle arrest in vascular smooth muscle cells in response to heparin
Keywords: سیکلین وابسته به کیناز 2; IFN; interferon; PKR; protein kinase, RNA-activated; VSMC; vascular smooth muscle cell; Cdk2; cyclin-dependent kinase 2; STAT1; signal transducer and activator of transcription-1; ds; double-stranded; JAK1; janus kinase 1; ATRA; all-trans retinoic acid; F
Characterization of Cdc2 kinase in the red claw crayfish (Cherax quadricarinatus): Evidence for its role in regulating oogenesis
Keywords: سیکلین وابسته به کیناز 2; Cdc2; cyclin-dependent kinase 2; MPF; maturation-promoting factor; GVBD; germinal vesicle breakdown; GSI; gonadosomatic index; PBS; phosphate buffered saline; IHC; immunohistochemical; RT-PCR; real-time reverse transcription polymerase chain reaction; qRT
MicroRNA profiling during rat ventricular maturation: A role for miR-29a in regulating cardiomyocyte cell cycle re-entry
Keywords: سیکلین وابسته به کیناز 2; miRNA; microRNAs; CCND2; cyclin D2; CDK2; cyclin-dependent kinase 2; P2; postnatal day 2; P4W; 4Â weeks of age; GAPDH; glyceraldehyde-3 phosphate dehydrogenase; UTR; untranslated regions; MicroRNA; Cardiomyocyte; Proliferation; Microarray; MicroRNA-29a;
Isradipine prevents rotenone-induced intracellular calcium rise that accelerates senescence in human neuroblastoma SH-SY5Y cells
Keywords: سیکلین وابسته به کیناز 2; [Ca2+]i; intracellular Ca2+ concentrations; CDK2; Cyclin-dependent kinase 2; DHP; dihydropyridine; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethylsulfoxide; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetra-acetic acid; ELISA; en
An ATP analog-sensitive version of the tomato cell death suppressor protein kinase Adi3 for use in substrate identification
Keywords: سیکلین وابسته به کیناز 2; Adi3; AvrPto-dependent Pto-interacting protein 3; CDK2; cyclin-dependent kinase 2; Gal83; galactose-specific gene 83; MBP; maltose binding protein; NDPK; nucleoside diphosphate kinase; PCD; programmed cell death; PKA; protein kinase A (or cAMP-dependent p
Phosphorylation prevents C/EBPβ from the calpain-dependent degradation
Keywords: سیکلین وابسته به کیناز 2; cdk2; cyclin-dependent kinase 2; C/EBP; CCAAT/enhancer-binding protein; GSK3β; glycogen synthase kinase-3β; PPAR; peroxisome proliferator-activated receptor; rC/EBPβ; recombinant C/EBPβ; C/EBPβ; Phosphorylation; Degradation; Calpain;
The BRCA1 alternative splicing variant Î14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells
Keywords: سیکلین وابسته به کیناز 2; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; AURKA; Aurora kinase A; BC; breast cancer; BRCA1/2; breast cancer-associated gene 1/2; BRCT; BRCA1 C-terminal domain; B2M; beta-2-microglobulin; Cdk2; cyclin-dependent kinase
Post-translational modification of pregnane x receptor
Keywords: سیکلین وابسته به کیناز 2; PXR; pregnane x receptor; NR; nuclear receptor; PCN; pregnenalone 16α-carbonitrile; Rif; rifampicin; G6Pase; glucose-6-phosphatase; PEPCK; phosphoenolpyruvate carboxykinase; CYP3A; cytochrome P450 3A; CREs; cyclic AMP response elements; PKA; cyclic AMP-d
Vitamin D3 up-regulated protein 1 deficiency accelerates liver regeneration after partial hepatectomy in mice
Keywords: سیکلین وابسته به کیناز 2; Akt; ERK1/2; Growth factor; Liver regeneration; VDUP1; BrdU; 5-bromo-2´-deoxy-uridine; CDK2; cyclin-dependent kinase 2; CDK4; cyclin-dependent kinase 4; EGF; epidermal growth factor; ERK1/2; extracellular signal-regulated kinase 1/2; GSK3β; glycogen syn
Vitamin D-dependent suppression of endothelin-induced vascular smooth muscle cell proliferation through inhibition of CDK2 activity
Keywords: سیکلین وابسته به کیناز 2; Vitamin D; Vascular smooth muscle cells; Cell cycle; Cyclin-dependent kinase 2
Integrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation
Keywords: سیکلین وابسته به کیناز 2; Progesterone receptor; Cell cycle; Cyclin D; p21; p27; Cyclin-dependent kinase 2
Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer’s disease
Keywords: سیکلین وابسته به کیناز 2; Cyclin-dependent kinase 5; p25; Cyclin-dependent kinase 2; Alzheimer’s disease
A flavonoid gossypin binds to cyclin-dependent kinase 2
Keywords: سیکلین وابسته به کیناز 2; Cyclin-dependent kinase 2; Flavonoids; Gossypin; QSAR
Cyclin-dependent kinase 2 signaling regulates myocardial ischemia/reperfusion injury
Keywords: سیکلین وابسته به کیناز 2; Myocardial ischemia; Cardioprotection; Apoptosis; Cyclin-dependent kinase 2; Retinoblastoma gene
Improved enrichment strategies for phosphorylated peptides on titanium dioxide using methyl esterification and pH gradient elution
Keywords: سیکلین وابسته به کیناز 2; Phosphorylation; Phosphopeptides; Enrichment; Phosphoproteomics; Titanium dioxide; Methyl esterification; Cyclin-dependent kinase 2;
Crystallography for protein kinase drug design: PKA and SRC case studies
Keywords: سیکلین وابسته به کیناز 2; PKA; Protein kinase A; PIFtide; Phosphoinositide-dependent kinase 1 interacting fragment peptide; CDK2; cyclin-dependent kinase 2; ATP; adenosine triphosphate; PKB; Protein kinase B; PKC; Protein Kinase C; PKG; Protein kinase G; PKI; protein kinase A inhi
Cyclin A2-CDK2 regulates embryonic gene activation in 1-cell mouse embryos
Keywords: سیکلین وابسته به کیناز 2; Cyclin A2; Cyclin-dependent kinase 2; Embryonic gene activation; 1-Cell mouse embryo; Phosphorylation of retinoblastoma protein;