دانلود مقالات ISI درباره Cyp + ترجمه فارسی

RelB attenuates cigarette smoke extract-induced apoptosis in association with transcriptional regulation of the aryl hydrocarbon receptor

Keywords: AhR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; bHLH/PAS; basic helix-loop-helix/PER-ARNT-Sim; COPD; chronic obstructive pulmonary disease; ChiP; chromatin immunoprecipitation; CYP; cytochrome P450; NQO1; NAD(P)H:quinone oxidoreductase 1; SOD; supe

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Sex-biased eicosanoid biology: Impact for sex differences in inflammation and consequences for pharmacotherapy

Keywords: AA; arachidonic acid; ATL; inflammatory aspirin-triggered 15-epi-lipoxin A4; COX; cyclooxygenase; CYP; cytochrome P450 enzyme; 5α-DHT; 5α-dihydrotestosterone; DiHETrE; dihydroxyeicosatrienoic acid; EC; endothelial cells; EETs; epoxyeicosatrienoic acid;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2017 سفارش ترجمه

The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p

Keywords: CYP; cytochrome P450; miRNAs; microRNAs; DMETs; drug metabolizing enzymes and transporters; Ago; argonaute RISC catalytic component; RISC; RNA-induced silencing complex; FBS; fetal bovine serum; EMSA; electrophoretic mobility shift assay; HCC; hepatocellu

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

CYP epoxygenase-derived H2O2 is involved in the endothelium-derived hyperpolarization (EDH) and relaxation of intrarenal arteries

Keywords: ACh; acetylcholine; [Ca2+]i; calcium intracellular concentration; COX; cyclooxygenase; CYP; cytochrome P450; DHETE; dihydroxyeicosatetraenoic acid; EC; endothelial cell; EDH; endothelium-derived-hyperpolarization; EDHFs; endothelium-derived hyperpolarizin

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal

Keywords: CAR; constitutive androstane receptor; CDK2; cyclin-dependent kinase 2; ChIP assay; chromatin immunoprecipitation assay; CYP; cytochrome P450; FOXO1; forkhead box protein O1; PCK1; phosphoenolpyruvate carboxykinase 1; PPARα; peroxisome proliferator-activ

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Quantitative Analyses of the Influence of Parameters Governing Rate-Determining Process of Hepatic Elimination of Drugs on the Magnitudes of Drug-Drug Interactions via Hepatic OATPs and CYP3A Using Physiologically Based Pharmacokinetic Models

Keywords: cytochrome P450; drug interaction; hepatic clearance; mathematical model; organic anion-transporting polypeptide transporters; pharmacokinetics; AUC; area under the plasma concentration-time curve; CL; clearance; CLint,all; overall hepatic intrinsic cle

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Indazole-based ligands for estrogen-related receptor α as potential anti-diabetic agents

Keywords: Estrogen-related receptor α; ERRα; Nuclear receptor; Anti-diabetic; Metabolic syndrome; Indazole; Thiazolidenedione; TZD; Insulin resistance; ERR; estrogen-related receptor; ER; estrogen receptor; ERE; estrogen response element; ERRE; estrogen-related r

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2017 سفارش ترجمه

DNA adducts induced by food mutagen PhIP in a mouse model expressing human sulfotransferases 1A1 and 1A2

Keywords: CYP; cytochrome P450; 2′-deoxyguanosine-PhIP; C8-(2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-N2-yl)-2′-deoxyguanosine; h; human; hSULT mice; FVB mice expressing human sulfotransferases 1A1 and 1A2; NAT; N-acetyltransferase; PhIP; 2-amino-1-methyl

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Evaluation of possible inhibition of human liver drug metabolizing cytochromes P450 by two new acetylcholinesterase oxime-type reactivators

Keywords: Acetylcholinesterase; Cytochrome P450; CYP; AChE reactivation; Oximes; K027; K203; Human microsomes;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Severe Vincristine-induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case Study

Keywords: adverse drug event; CEP72; CYP; vincristine; neuropathy; P-glycoprotein; pharmacogenetics; phenotyping;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery and development of benzo-[1,2,4]-triazolo-[1,4]-oxazepine GPR142 agonists for the treatment of diabetes

Keywords: GPR142; g-protein coupled receptor 142; HTS; high throughput screen; PPB; plasma protein binding; CYP; cytochrome P450; GPR142; Diabetes; Wild-type knock-out study;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Vitamin D metabolism and regulation in pediatric MSCs

Keywords: 1α,25(OH)2D; 1α,25-dihydroxyvitamin D; 25(OH)D; 25-hydroxyvitamin D; BMI; body mass index; CYP; cytochrome P450; DBP; vitamin D binding protein; ER; estrogen receptor; FGF23; fibroblast growth factor 23; hMSC; human marrow stromal cell, a.k.a. mesenchym

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Genotyping of coding single nucleotide variants of the hOAT2[SLC22A7] gene in Japanese patients with non-viral liver tumor

Keywords: cSNPs; coding single nucleotide polymorphisms; CYP; cytochrome P450; DNA; deoxyribonucleic acid; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; hOAT2; human organic anion transporter 2; hURAT1; urate transporter 1; HWE; Hardy-Weinberg equilibrium;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Constitutive expression of cytochrome P450 in foetal and adult porcine livers-Effects of body weight

Keywords: Ontogeny; Birth-Weight; Age; Life-stage; Microsomes; CYP; qPCR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction

Keywords: Human induced pluripotent stem cells; Hepatocyte; Drug metabolism; ATF5; c/EBPα; PROX1; Human iPS-HLCs; Human induced pluripotent stem cells-derived hepatocyte-like cells; HLCs; Hepatocyte-like cells; ATF5; Activating transcription factor 5; c/EBPα; CCA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Development of an optimized cytotoxicity assay system for CYP3A4-mediated metabolic activation via modified piggyBac transposition

Keywords: CYP; cytochrome P450; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; iPSCs; induced pluripotent stem cells; cDNA; complementary DNA; PB; piggyBac; PBase; piggyBac tranposase; BSO; L-buthionine-(S,R)-sulfoximine; CMV; cytomegalovir

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Sequential hydroxylation of vitamin D2 by a genetically engineered CYP105A1

Keywords: Cytochrome P450; CYP105; Protein engineering; Crystal structure; Vitamin D2; Sequential hydroxylation; 25(OH)D2; 25-hydroxyvitamin D2; 1α,25(OH)2D2; 1α,25-dihydroxyvitamin D2; CYP; cytochrome P450; VDR; vitamin D receptor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Protein expression of CYP1A1, CYP1B1, ALDH1A1, and ALDH2 in young patients with oral squamous cell carcinoma

Keywords: oral cancer; squamous cell carcinoma; aldehyde dehydrogenase; cytochrome P450; CYP; ALDH; young age

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Relationship between the plasma fentanyl and serum 4β-hydroxycholesterol based on CYP3A5 genotype and gender in patients with cancer pain

Keywords: Fentanyl; Transdermal system; 4β-Hydroxycholesterol; CYP3A5; Gender; Pharmacokinetics; Cancer pain; 4β-OHC; 4β-hydroxycholesteol; CYP; cytochrome P450;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

2, 4-Dichloro-6-nitrophenol, a photonitration product of 2, 4-dichlorophenol, caused anti-androgenic potency in Chinese rare minnows (Gobiocypris rarus)

Keywords: Chinese rare minnows; 2,4-Dichloro-6-nitrophenol; Environmental transformation products; Endocrine disruption; DCNP; 2,4-dichloro-6-nitrophenol; DCP; 2,4-dichlorophenol; VTG; vitellogenin; T; testosterone; E2; estradiol; ER; estrogen receptor; AR; androge

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

New brominated flame retardants and their metabolites as activators of the pregnane X receptor

Keywords: CYP; cytochrome P450; PCR; polymerase chain reaction; PPAR; peroxisome proliferator activated receptor; PXR; pregnane X receptor; TBB; 2-ethylhexyl 2,3,4,5-tetrabromobenzoate; TBPH; bis(2-ethylhexyl) tetrabromophthalate; TBBA; 2,3,4,5-tetrabromobenzoic ac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The fungicide thiabendazole causes apoptosis in rat hepatocytes

Keywords: APAF-1; apoptosis protease activating factor-1; CYP; cytochrome P450; DISC; death inducing signaling complex; EROD; ethoxyresorufin-o-deethylase; FADD; Fas-associated death domain; FBS; fetal bovine serum; FCCP; carbonylcyanide p-trifluoromethoxyphenylhyd

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Disruption of redox homeostasis and carcinogen metabolizing enzymes changes by administration of vitamin E to rats

Keywords: APND; aminopyrine N-demethylase; b.w.; body weight; CAT; catalase; CEHC; carboxyethylhydroxychromane; CYP; cytochrome P-450; CYP-red; NADPH-(CYP)-c-reductase; DCPIP; dichlorophenolindophenol; EPR; electronic paramagnetic resonance; EROD; ethoxyresorufin O

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Comparative study of CYP2B1/2 induction and the transport of bilirubin and taurocholate in rat hepatocyte-mono- and hepatocyte-Kupffer cell co-cultures

Keywords: B; bilirubin; Bsep; bile salt export pump; CYP; cytochrome P-450; GdCl3; gadolinium(III) chloride; H/KC; hepatocyte-Kupffer-cell co-culture; HBSS; Hanks' balanced salt solution; HPLC; high-performance liquid chromatography; KC; Kupffer-cell; LPS; lipopoli

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Efavirenz biotransformation as an up-stream event of mood changes in HIV-infected patients

Keywords: EFV; efavirenz; cART; combined antiretroviral therapy; CNS; central nervous system; CSF; cerebrospinal fluid; CYP; cytochrome P450; UGT; UDP-glucuronosyltransferase; 8-OH-EFV; 8-hydroxy-efavirenz; 7-OH-EFV; 7-hydroxy-efavirenz; 8,14-diOH-EFV; , 8,14-dihyd

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

An ultra-high performance liquid chromatography-tandem mass spectrometric assay for quantifying 3-ketocholanoic acid: Application to the human liver microsomal CYP3A-dependent lithocholic acid 3-oxidation assay

Keywords: CYP; cytochrome P450; CYP3A; cytochrome P450 3A; DMSO; dimethyl sulfoxide; HPLC-UV; high-performance liquid chromatography-ultraviolet spectroscopy; 3-KCA; 3-ketocholanoic acid; LC-MS/MS; liquid chromatography-tandem mass spectrometry; LCA; lithoc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Omeprazole induces heme oxygenase-1 in fetal human pulmonary microvascular endothelial cells via hydrogen peroxide-independent Nrf2 signaling pathway

Keywords: AhR; aryl hydrocarbon receptor; ARDS; acute respiratory distress syndrome; ARE; antioxidant response element; BPD; bronchopulmonary dysplasia; CYP; cytochrome P450; DMSO; dimethyl sulfoxide; HPMEC; human pulmonary microvascular endothelial cells; HO-1; he

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacokinetics, exposure-cognition, and exposure-efficacy relationships of perampanel in adolescents with inadequately controlled partial-onset seizures

Keywords: AED; antiepileptic drug; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; Cav,ss; average steady-state plasma concentration at; CDR; Cognitive Drug Research system; CNS; central nervous system; CL/F; apparent clearance; CYP; cytochrome P450; IIV

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Fungal elicitors enhance ginsenosides biosynthesis, expression of functional genes as well as signal molecules accumulation in adventitious roots of Panax ginseng C. A. Mey

Keywords: NO; nitric oxide; SA; salicylic acid; JA; jasmonic acid; GPS; geranyl diphosphate synthase; FPS; farnesyl diphosphate synthase; SS; squalene synthase; SE; squalene epoxidase; DS; dammarenediol synthase; CYP; cytochrome P450; UGT; UDP-glycosyltransferases;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A Physiologically Based Pharmacokinetic Model to Describe Artemether Pharmacokinetics in Adult and Pediatric Patients

Keywords: clinical pharmacokinetics; CYP enzymes; drug metabolizing enzymes; elimination; hepatic clearance; interspecies scaling; physiologically based pharmacokinetic modeling; preclinical pharmacokinetics; simulations; AUC; area under the plasma concentration-ti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Culturing of HepG2 cells with human serum improve their functionality and suitability in studies of lipid metabolism

Keywords: CYP; cytochrome P450; LDLR; low density lipoprotein receptor; MTP; microsomal triglyceride transfer protein; PCSK9; proprotein subtilisin/kexin type 9; HepG2; Human serum; FBS; Lipoproteins; Bile acids;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

21-Hydroxylase deficiency-induced congenital adrenal hyperplasia in 230 Chinese patients: Genotype–phenotype correlation and identification of nine novel mutations

Keywords: CAH, congenital adrenal hyperplasia; 21-OHD, 21-hydroxylase deficiency; CYP21A2, cytochrome P450, family 21, subfamily A, polypeptide 2; MLPA, multiplex ligation-dependent probe amplification; SW, salt-wasting; SV, simple virilizing; NC, nonclassical; CYP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of Long-Lasting Oatp Inhibition by Typical Inhibitor Cyclosporine A and In Vitro-In Vivo Discrepancy in Its Drug Interaction Potential in Rats

Keywords: drug interactions; in vitro/in vivo correlations; pharmacokinetics; protein binding; transporters; CYP enzymes; hepatocytes; organic anion-transporting polypeptide transporters; multidrug resistance transporters; solute transporters; ABT; 1-aminobenzotr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes

Keywords: CYP; cytochrome P450; miRNA; microRNA; DMETs; drug metabolizing enzymes and transporters; CAR; constitutive androstane receptor; PXR; pregnane X receptor; RE; response element; 3′-UTR; 3′-untranslated region; SULT; sulfotransferase; Ago; argonaute RIS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Abscisic acid content and the expression of genes related to its metabolism during maturation of triticale grains of cultivars differing in pre-harvest sprouting susceptibility

Keywords: ABA; abscisic acid; ABA8′OH; ABA 8′-hydroxylase; CYP; cytochrome P450; DAP; days after pollination; UGT; uridine diphosphate glucosyltransferase; NCED; 9-cis-epoxycarotenoid dioxygenase; PHS; pre-harvest sprouting; ZEP; zeaxanthin epoxidase; Abscisic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer

Keywords: 4′-OH DF; 4′-hydroxy diclofenac; 5-OH DF; 5-hydroxy diclofenac; 7-HC; 7-hydroxycoumarin; APAP; acetaminophen; CYP; cytochrome P450; DMEM; Dulbecco's modified Eagle's medium; DF; diclofenac; OH-TC; hydroxy tolcapone; TC; tolcapone; GST; glutathione-S-t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

PXR variants: the impact on drug metabolism and therapeutic responses

Keywords: AF; activating function; BAMCA; bacterial artificial chromosome array-based methylated CpG island amplification; CYP; cytochrome P450; GST; glutathione S-transferase; MDR; multidrug resistance protein; NHR; nuclear hormone receptor; P-gp; P-glycoprotein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

CYP2C8-mediated interaction between repaglinide and steviol acyl glucuronide: In vitro investigations using rat and human matrices and in vivo pharmacokinetic evaluation in rats

Keywords: CYP2C8; Steviol acyl glucuronide; Repaglinide; Reversible inhibition; Food-drug interaction; AUC; area under the plasma time-concentration curve; Cmax; plasma maximum concentration; CYP; cytochrome P450; HLM; human liver microsomes; RLM; rat liver microso

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleThe cyclophilin-inhibitor alisporivir stimulates antigen presentation thereby promoting antigen-specific CD8+ T cell activation

Keywords: HCV; hepatitis C virus; CsA; cyclosporine A; MHC; major histocompatibility complex; Cyp; cyclophilin; E:T ratio; effector-to-target ratio; NS5BEM; epitope-matched HCV non-structural protein 5B; IFN; interferon; b2m; beta-2 microglobulin; GLuc; Gaussia-luc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Selective suppression of the human aryl hydrocarbon receptor function can be mediated through binding interference at the C-terminal half of the receptor

Keywords: AHR, aryl hydrocarbon receptor; ARNT, aryl hydrocarbon receptor nuclear translocator; 3MC, 3-methylcholanthrene; FICZ, 6-formylindolo(3,2-b)carbazole; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; αNF, α-naphthoflavone; CH, CH223191; BaP, benzo[a]pyrene; CYP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The factor in EDHF: Cytochrome P450 derived lipid mediators and vascular signaling

Keywords: BKCa; large conductance KCa channels; COX; cyclooxygenase; CYP; cytochrome P450; DHA; docosahexaenoic acid; DHDP; dihydroxydocosapentaenoic acids; DHET; dihydroxyeicosatrienoic acids; DiHOME; dihydroxyoctadecenoic acid; EDHF; endothelium-derived hyperpola

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver

Keywords: ALF; acute liver failure; NAPQI; N-acetyl-p-benzoquinone imine; UGT; UDP-glucuronosyltransferase; SULT; sulfotransferase; CYP; cytochrome P450; 3′-UTR; 3′-untranslated region; SNP; single nucleotide polymorphism; miRNA; microRNA; UDPGA; uridine diphos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis

Keywords: AA; arachidonic acid; AMD; age-related macular degeneration; CNV; choroidal neovascularization; COX; cyclooxygenases; CYP; cytochrome P450 epoxygenase; DHA; docosahexaenoic acid; EDP; epoxydocosapentaenoic acid; EET; epoxyeicosatrienoic acid; EPA; eicosap

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide

Keywords: AOS; allene oxide synthase(s); CP; chiral phase; COX; cyclooxygenase(s); CYP; cytochrome P450; DiHODE; dihydroxyoctadecadienoic acid; DOX; dioxygenase(s); EAS; epoxyalcohol synthase; 9(10)-EODE; 9(10)-epoxy-10,12(Z)-octadecadienoic acid; 9,10-DiHOME; 9,10

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNAs as key mediators of hepatic detoxification

Keywords: CYP; cytochrome p450; UGTs; UDP glycosyltransferases; GSTs; glutathione-S-transferases; SULTs; sulfotransferases; OATs; organic anion transporters; MRPs; multidrug-resistance proteins; DGCR8; DiGeorge Syndrome Critical Region Gene 8; RISC; RNA-induced sil

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Preparation and characterization of Chinese yam polysaccharide PLGA nanoparticles and their immunological activity

Keywords: CYP; Chinese yam polysaccharide; PLGA; poly(D,L-lactic-co-glycolic acid); CYPP; Chinese yam polysaccharide PLGA nanoparticles; BP; blank PLGA nanoparticles; NP; nanoparticle; PE; primary emulsion; RSM; response surface methodology; LPS; lipopolysaccharide

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium

Keywords: CYP; cytochrome P450 epoxygenase; EET; epoxyeicosatrienoic acid; AA; arachidonic acid; COX; cyclooxygenase; LOX; lipoxygenase; MCAO; middle cerebral artery occlusion; Stroke; Eicosanoids; Vasodilation; Inflammation; Cerebral blood flow;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Enhancing cytochrome P450-mediated conversions in P. pastoris through RAD52 over-expression and optimizing the cultivation conditions

Keywords: AOX1; alcohol oxidase 1; AtCPR; Arabidopsis thaliana CPR; CDW; cell dry weight; CPR; cytochrome P450 reductase; CYP; cytochrome P450 enzyme; DWP; deep-well plate; FPP; farnesyl pyrophosphate; hCPR; human CPR; HPO; Hyoscyamus muticus premnaspirodiene oxyge

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells

Keywords: AhR; aryl hydrocarbon receptor; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; CYP; cytochrome P-450; DEP; diesel exhaust particle; DEPe; diesel exhaust particle extract; DMSO; dimethyl sulfoxide; EGR1; early growth response 1; ERK; extracellular

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo

Keywords: AA; aristolochic acid; AAI; aristolochic acid I; AAII; aristolochic acid II; AAIa; aristolochic acid Ia; AAN; aristolochic acid nephropathy; BEN; Balkan endemic nephropathy; bw; body weight; cT; cycle threshold; CYP; cytochrome P450; dA-AAI; 7-deoxyadenos

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه