دانلود مقالات ISI درباره Ddi + ترجمه فارسی

Original ArticlePharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR

Keywords: AE; adverse event; AUC; area under the curve; BID; twice daily; CF; cystic fibrosis; CFQ-R; Cystic Fibrosis Questionnaire-Revised; CFTR; cystic fibrosis transmembrane conductance regulator; DDI; drug-drug interaction; ECG; electrocardiogram; ER; endopla

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia

Keywords: DDI; drug-drug interaction; β-EST; β-estradiol; HLM; human liver microsomes; IV-IVE; in vitro-in vivo extrapolation; KI; kinase inhibitor; 4MU; 4-methylumbelliferone; LAP; lapatinib; NSB; non-specific binding; PAZ; pazopanib; PRO; propofol; REG; r

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Prediction of renal transporter-mediated drug-drug interactions for a drug which is an OAT substrate and inhibitor using PBPK modelling

Keywords: AUC; area under the curve; DDI; drug-drug interaction; fu; fraction unbound; IC50; inhibition constant; IV; intravenous; IVIVE; in vitro/in vivo extrapolation; Ki; inhibition constant; OAT; organic anion transporter; PBPK; physiologically based pharmacoki

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation

Keywords: Drug-drug interactions; CYP2D6; Bupropion; Enzyme regulation; In vitro to in vivo extrapolation; AUC; area under plasma concentration time curve; CYP; cytochrome P450; DDI; drug-drug interaction; fm; fraction metabolized; IVIVE; in vitro to in vivo extrap

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

In Vitro-In Vivo Extrapolation of Metabolism- and Transporter-Mediated Drug-Drug Interactions-Overview of Basic Prediction Methods

Keywords: drug interaction; cytochrome P450s; membrane transport/transporters; regulatory; guidance/guideline; ADME; absorption, distribution, metabolism and excretion; BCRP; breast cancer resistance protein; CYP; cytochrome P-450; d; induction calibration factor;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Preincubation-dependent and long-lasting inhibition of organic anion transporting polypeptide (OATP) and its impact on drug-drug interactions

Keywords: AUC; area under the plasma concentration-time curve; AUCR; increase ratio in the area under the plasma concentration-time curve; BIM-I; bisindolylmaleimide I; BSP; sulfobromophthaleine; CCK8; cholecystokinine octapeptide; CsA; cyclosporin A; DDI; drug-dru

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Confocal laser-induced fluorescence detector for narrow capillary system with yoctomole limit of detection

Keywords: LIF; laser-induced fluorescence; DNA; deoxyribonucleic acid; BaNC; bare narrow capillary; HDC; hydrodynamic chromatography; LOD; limit of detection; LDR; linear dynamic range; FIA; flow injection analysis; i.d.; inner diameter; o.d.; outer diameter; CE; c

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Predicting CD4 count changes among patients on antiretroviral treatment: Application of data mining techniques

Keywords: CD4 count change; Antiretroviral treatment; Computational methods; Random Forest; Neural Network; J48, Decision tree; ABC; Abacavir; ddI; Didanosine; d4T; Stavudin; EFV; Efavirenz; FTC; Emotricitabine; LPV/r; Lopinavir/ritonavir; NFV; Nelfinavir; NNRTI; N

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of Renal Transporter Inhibition Using Creatinine as a Substrate In Vitro to Assess the Clinical Risk of Elevated Serum Creatinine

Keywords: renal transporter; drug interactions; in vitro-in vivo correlation; renal clearance; inhibition; AUC; area under the concentration curve; CLcr; creatinine renal clearance; Cmax; maximal total plasma concentration; Cmax,u; maximal unbound plasma concen

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model

Keywords: physiologically based pharmacokinetic modeling; transporters; statin; absorption; organic anion-transporting polypeptide; drug-drug interaction; AUC; area under the plasma concentration-time curve; Cmax; maximum plasma concentration; CLint,T; transporter-

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Current In Vitro Methods to Determine Hepatic Kpuu: A Comparison of Their Usefulness and Limitations

Keywords: active transport; passive diffusion/transport; hepatic metabolism; biliary excretion; distribution; disposition; tissue partition; protein binding; hepatocytes; human liver microsomes; ABT; 1-aminobenzotriazole; AFE; average fold error; CLint; intrinsic c

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Simulations of Cytochrome P450 3A4-Mediated Drug-Drug Interactions by Simple Two-Compartment Model-Assisted Static Method

Keywords: bioavailability; cytochrome P450; drug interaction; dynamic simulation; first pass metabolism; hepatic clearance; intestinal metabolism; pharmacokinetics; simulations; parallel tube model; Ae (Ae,oral); dose fractions of urinary excreted unchanged drug af

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Pretreatment With Rifampicin and Tyrosine Kinase Inhibitor Dasatinib Potentiates the Inhibitory Effects Toward OATP1B1- and OATP1B3-Mediated Transport

Keywords: drug transport; drug interactions; organic anion-transporting polypeptide transporters; hepatocytes; hepatic transport; pharmacokinetics; physiologically based pharmacokinetic modeling; AUC; area under the plasma concentration-time curve; CsA; cyclosporin

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Keywords: API; active pharmaceutical ingredient; AUC; area under the curve; BCS; biopharmaceutics classification system; BP; blood-to-plasma ratio; Cmax; maximum concentration; CL; clearance; Do; dose number according to BCS; DDI; drug-drug interaction; EFPIA; Euro

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Quantitative Analyses of the Influence of Parameters Governing Rate-Determining Process of Hepatic Elimination of Drugs on the Magnitudes of Drug-Drug Interactions via Hepatic OATPs and CYP3A Using Physiologically Based Pharmacokinetic Models

Keywords: cytochrome P450; drug interaction; hepatic clearance; mathematical model; organic anion-transporting polypeptide transporters; pharmacokinetics; AUC; area under the plasma concentration-time curve; CL; clearance; CLint,all; overall hepatic intrinsic cle

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Determinants of Intestinal Availability for P-glycoprotein Substrate Drugs Estimated by Extensive Simulation With Mathematical Absorption Models

Keywords: drug-drug interaction; P-glycoprotein; physiologically based pharmacokinetic model; modeling and simulation; intestinal absorption; substrate drug; CLh; hepatic clearance; CLr; renal clearance; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; EQ

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

Short communicationInteractions between non-vitamin K oral anticoagulants and antiepileptic drugs

Keywords: AED; antiepileptic drug; AF; atrial fibrillation; DDI; drug-drug interaction; INR; International Normalized Ratio; NOAC; non-vitamin K antagonist oral anticoagulant; OAC; oral anticoagulant; VKA; vitamin-K antagonist; Atrial fibrillation; Stroke; Seizur

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Clinical Exposure Boost Predictions by Integrating Cytochrome P450 3A4-Humanized Mouse Studies With PBPK Modeling

Keywords: clinical pharmacokinetics; CYP enzymes; drug interaction; drug metabolizing enzymes; elimination; hepatic clearance; interspecies scaling; physiologically based pharmacokinetic modeling; preclinical pharmacokinetics; simulations; AUC; area under the plasm

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Identification and characterization of human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of ursolic acid

Keywords: Ursolic acid; UDP-glucuronosyltransferases; Metabolism pathway; Metabolism characterization; UA; ursolic acid; HLMs; human liver microsomes; HIMs; human intestinal microsomes; UGTs; UDP-glucuronosyltransferases; DDI; drug-drug interactions; RILD; Resear

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of Long-Lasting Oatp Inhibition by Typical Inhibitor Cyclosporine A and In Vitro-In Vivo Discrepancy in Its Drug Interaction Potential in Rats

Keywords: drug interactions; in vitro/in vivo correlations; pharmacokinetics; protein binding; transporters; CYP enzymes; hepatocytes; organic anion-transporting polypeptide transporters; multidrug resistance transporters; solute transporters; ABT; 1-aminobenzotr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation

Keywords: data mining; data science; drug-drug interaction; long QT syndrome; APD70; action potential duration at 70% of repolarization; DDI; drug-drug interaction; ECG; electrocardiogram; EHR; electronic health records; FAERS; Food and Drug Administration adverse

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

An update on the role of intestinal cytochrome P450 enzymes in drug disposition

Keywords: AUC; area under concentration-time curve; CPR; NADPH-cytochrome P450 reductase; DDI; drug-drug interaction; GFJ; grapefruit juice; IECN; intestinal epithelium-specific Cpr-null; LCN; liver-specific Cpr-null; P450 (or CYP); cytochrome P450; P-gp; P-glyco

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Insights into CYP2B6-mediated drug-drug interactions

Keywords: CAR; constitutive androstane receptor; C/EBP; CCAAT/enhancer-binding protein; CHOP; cyclophosphamide-doxorubicin-vincristine-prednisone; CITCO; (6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime); COUP-TF; chic

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

NS5A resistance leading to failure of 24-week therapy with sofosbuvir/ledipasvir and ribavirin for the treatment of hepatitis C genotype 1a infection in a HIV-1 co-infected patient

Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; cART; combination antiretroviral therapy; DAA; direct-acting antiviral; DDI; drug-drug interaction; EOTR; end-of-treatment response; GT; genotype; HCV; hepatitis C virus; HIV-1; human immun

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice

Keywords: ABC; ATP-binding cassette; AUC; area under the concentration-time curve; DDI; drug-drug interactions; E2G; estradiol 17β-d-glucuronide; i.v.; intravenous; OATP; organic anion-transporting polypeptide; TKI; tyrosine kinase inhibitor; UGT1A1; UDP-glucuro

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Simultaneous determination of 2′,3′-dideoxyinosine and the active metabolite, 2′,3′-dideoxyadenosine-5′-triphosphate in human peripheral-blood mononuclear cell by HPLC–MS/MS and the application to cell pharmacokinetics

Keywords: HPLC–MS/MS; ddI; dA-TP; Cell pharmacokinetics; Interaction

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Perinatal dioxin exposure and the neurodevelopment of Vietnamese toddlers at 1 year of age

Keywords: 2,3,7,8-TetraCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; 1,2,3,7,8-PentaCDD; 1,2,3,7,8-pentachlorodibenzo-p-dioxin; 1,2,3,4,7,8-HexaCDD; 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin; 1,2,3,6,7,8-HexaCDD; 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin; 1,2,3,7,8,9-HexaCDD

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleSTARTVerso1: A randomized trial of faldaprevir plus pegylated interferon/ribavirin for chronic HCV genotype-1 infection

Keywords: HCV; hepatitis C virus; PI; protease inhibitor; PegIFN; peginterferon; RBV; ribavirin; SVR; sustained virologic response; DDI; drug-drug interaction; BID; twice daily; ETS; early treatment success; TD; target detected; TND; target not detected; EVR; ear

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities

Keywords: ACAT; acyl CoA:cholesterol acyltransferase; ADME; absorption, distribution, metabolism and excretion; APCI; atomospheric pressure chemical ionization; CM; chylomicron; dba; dibenzylideneacetone; CYP; cytochrome P450; DDI; drug-drug interaction; DGAT; ac

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2015 سفارش ترجمه

Arabidopsis STAYGREEN-LIKE (SGRL) promotes abiotic stress-induced leaf yellowing during vegetative growth

Keywords: CBB; Coomassie Brilliant Blue; Chl; chlorophyll; CCE; chlorophyll catabolic enzyme; CLH; chlorophyllase; DDI; days of dark incubation; DST; days of salt treatment; GFP; green fluorescent protein; LHCI; light-harvesting complex I; LHCII; light-harvesting c

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Therapy of type 1 diabetes with CD4+CD25highCD127-regulatory T cells prolongs survival of pancreatic islets - Results of one year follow-up

Keywords: anti-GAD; glutamic acid decarboxylase autoantibodies; anti-IA2; tyrosine phosphatase-related islet antigen 2 autoantibodies; b.w; body weight; cGMP; current good manufacturing practice; DDI; daily dose of insulin; DM1; type 1 diabetes mellitus; GvHD; graf

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Methotrexate-bestatin interaction: Involvement of P-glycoprotein and organic anion transporters in rats

Keywords: MTX; methotrexate; DDI; drug-drug interaction; P-gp; P-glycoprotein; OAT; organic anion transporter; MRP; multidrug resistance-associated protein; BCRP; breast cancer resistance protein; OATP; organic anion transporting polypeptide; KRB; Krebs-Ringer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling

Keywords: AUC; area under the plasma concentration-time curve; DDI; drug-drug interaction; CLint; intrinsic clearance; BCRP; Breast Cancer Resistance Protein; HEK293; Human Embryonic Kidney 293 (cell-line); MRP; Multidrug resistance-associated protein; NTCP; Sodi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Frontiers in Liver TransplantationDrug-drug interactions with oral anti-HCV agents and idiosyncratic hepatotoxicity in the liver transplant setting

Keywords: ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; AUC; Area under the curve; BOC; Boceprevir; BSEP; Bile salt export pump; Cmax; Maximum concentration; CNI; Calcineurin inhibitors; CYP; Cytochrome P450; DAA; Direct acting antivirals; DDI; Dr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Epidemiology and impact of HIV coinfection with Hepatitis B and Hepatitis C viruses in Sub-Saharan Africa

Keywords: 3TC; Lamivudine; AOR; Adjusted Odds Ratio; ADV; adefovir; ALT; alanine transaminase; Anti-HBcAb; antibody to Hepatitis B core antigen; Anti-HBeAb; antibody to Hepatitis B e-antigen; Chronic hepatitis B; persistence of HBsAg >6months; d4T; Stavudine; ddI;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Coupling ultra-high-pressure liquid chromatography with mass spectrometry for in-vitro drug-metabolism studies

Keywords: ADC; Analog-to-digital converter; ADMET; Absorption, distribution, metabolism, excretion and toxicity; APCI; Atmospheric pressure chemical ionization; CYP; Cytochrome P450; DDI; Drug-drug interaction; DMPK; Drug metabolism and pharmacokinetics; DT; Dwell

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

7-Hydroxymethyl chlorophyll a reductase functions in metabolic channeling of chlorophyll breakdown intermediates during leaf senescence

Keywords: CBB; Coomassie Brilliant Blue; Chl; chlorophyll; CCE; chlorophyll catabolic enzyme; DDI; days of dark incubation; GFP; green fluorescent protein; HMChl a; 7-hydroxymethyl chlorophyll a; LHCI; light-harvesting complex I; LHCII; light-harvesting complex II;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Comparative analysis of genetic toxicity of antiretroviral combinations in somatic cells of Drosophila melanogaster

Keywords: NRTI; nucleoside reverse transcriptase inhibitor; HAART; highly active antiviral therapy; AZT; 3′-azido-3′-deoxythymidine; ddI; 2′,3′-dideoxyinosine; 3TC; [−] 2′-deoxy-3′-thiacytidine; d4T; 3′-deoxy-2′,3′-didehydrothymidine; SMART; som

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Keywords: Biotransformation; Cytochrome P450 monooxygenase; NADPH:cytochrome P450 reductase; Pharmacogenetics; Polymorphism; Xenobiotic; ADME; absorption, distribution, metabolism, excretion; ADR; adverse drug reaction; AhR; aromatic hydrocarbon receptor; CNV; copy

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2013 سفارش ترجمه

A P-gp vesicular transport inhibition assay – Optimization and validation for drug–drug interaction testing

Keywords: Vesicular uptake; P-glycoprotein; ABCB1; N-methyl quinidine; DDI; Human cell membrane

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Twelve-Month Frequency of Drug-Metabolizing Enzyme and Transporter-Based Drug-Drug Interaction Potential in Patients Receiving Oral Enzyme-Targeted Kinase Inhibitor Antineoplastic Agents

Keywords: CYP; cytochrome; DDI; drug-drug interaction; FDA; Food and Drug Administration; HICL; Hierarchical Ingredient Code List; OAD; enzyme-targeted kinase inhibitor oral antineoplastic drug; p-gp; P-glycoprotein;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Impact of a drug-drug interaction intervention on pharmacy and medical students’ knowledge and attitudes: A 1-year follow-up

Keywords: Drug-drug interaction; Drug interaction knowledge; DDI; Pharmacy education; Medical education

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein

Keywords: AUC0-6 h; Area under the plasma concentration time curve from 0 to 6 h; B/P; Brain/Plasma; BSA; Bovine serum albumin; Cmax; Maximum drug concentration; CNS; Central nervous system; DDI; Drug-drug interaction; EPS; Extrapyramidal symptoms; FBS; Fetal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11)

Keywords: ACN; anthocyanin; BCRP; breast cancer resistance protein; Cmax; maximum plasma concentration; CHO; Chinese hamster ovary; DDI; drug-drug interaction; ES; estrone sulfate; fu; fraction unbound in plasma; FDA; Food and Drug Administration; HEK; human embr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba

Keywords: ART; antiretroviral therapy; CI; confidence interval; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside RTI; PI; protease inhibitor; FCR; full-class resistance; CRF; circulating recombinant form; HIV; human immunodeficiency virus; MD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Induction of cytochrome P450 3A by Shexiang Baoxin Pill and its main components

Keywords: P450; cytochrome P450; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; TCM; traditional Chinese medicine; SBP; Shexiang Baoxin Pill; MDZ; midazolam; CHD; coronary heart diseases; MUS; muscone; TES; testosterone; GRf; ginsenoside Rf; GRg1; ginseno

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Comparative study on antiproliferation properties and cellular antioxidant activities of commonly consumed food legumes against nine human cancer cell lines

Keywords: CAA; cellular antioxidant activity; DDI; dose-dependent inhibition; DPPH; 2-diphenyl-1-picryhydrazyl radical; FRAP; ferric reducing antioxidant power; NDD; non-dose-dependent; ORAC; oxygen radical absorbing capacity; PAC; procyanidin content; PRSC; peroxy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleThe role of nucleoside and nucleotide analogues in nodular regenerative hyperplasia in HIV-infected patients: A case control study

Keywords: NRH; nodular regenerative hyperplasia; NCPH; non-cirrhotic portal hypertension; HIV; human immunodeficiency virus; ddI; didanosine; IQR; interquartile range; ART; antiretroviral treatment; HAART; highly active antiretroviral treatment; BMI; body mass inde

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation

Keywords: ACN; acetonitrile; APAP; acetaminophen; CYP1A2; cytochrome P450 1A2 enzyme; CYP2B6; cytochrome P450 2B6 enzyme; CYP2C19; cytochrome P450 2C19 enzyme; CYP2D6; cytochrome P450 2D6 enzyme; CYP3A4; cytochrome P450 3A4 enzyme; CYP450; cytochrome P450 enzymes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه