Keywords: Immunodeficiency; Foals; DNA-PKcs; Deletion; Fragment analysis;
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: HPCs; hepatic progenitor cells; mtROS; mitochondrial reactive oxygen species; DEN; diethylnitrosamine; SPCs; stem/progenitor cells; HSCs; hematopoietic stem cells; NSCs; neural stem cells; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum;
Keywords: Severe combined immunodeficiency; radiation sensitivity; hematopoietic cell transplantation; nonhomologous end joining; DNA repair; ART-SCID; Artemis-deficient severe combined immunodeficiency; ATG; Antithymocyte globulin; DNA-PKcs; DNA-dependent protein
Keywords: Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Keywords: 17-AAG; 17-(Allylamino)-17-demethoxygeldanamycin; 17-DMAG; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin; AKT; v-akt murine thymoma viral oncogene homolog; APC; antigen presenting cell; ATM; Ataxia telangiectasia mutated; ATR; Ataxia telangiectasia
Keywords: PI3K/Akt; DNA repair; NHEJ; DNA-PKcs; Ionizing radiation; Radiotherapy;
Keywords: ATM; ataxia telangiectasia-mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; CI; combination index; CLL; chronic lymphocytic leukemic cells; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit;
Keywords: Non-homologous end joining; DNA-PKcs; Artemis, DNA ligase IV; XRCC4; XLF; Cernunnus; LIG4 syndrome;
Keywords: Alt-EJ; alternative end joining; APLF; aprataxin and polynucleotide kinase/phosphatase-like factor; ATM; ataxia-telangiectasia mutated; ATR; ATM-, Rad3-related; APTX; aprataxin; β-Casp; metallo-β-lactamase-associated CPSF Artemis SNM1 PSO2; BER; base ex
Keywords: ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; Chk2; checkpoint kinase 2; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DUSP; dual-specificity phosphatase; HIV; human immunodeficiency virus; IL; interleukin; MCP1; monocyte ch
Keywords: Space radiation; Solar particle event; Radiation countermeasures; Acute effects of radiation; Long-term effects of radiation; ARS; acute radiation sickness; aPTT; activated partial thromboplastin time; BBI; Bowman-Birk inhibitor; BBIC; BBI concentrate;
NOTCH1 modulates activity of DNA-PKcs
Keywords: DNA-PKcs; NOTCH1; DNA damage repair;
DNA damage, metabolism and aging in pro-inflammatory T cells
Keywords: EC; endothelial cell; ROS; reactive oxygen species; ATP; adenosine 5â²-triphosphate; ER; endoplasmic reticulum; mtDNA; mitochondrial DNA; ETC; electron transport chain; mROS; mitochondrial ROS; NADPH; nicotinamide adenine dinucleotide phosphate; TNF-α;
A qPCR assay for measuring the post-integrational DNA repair in HIV-1 replication
Keywords: HIV; Integration; DNA repair; qPCR; DNA-PK; DNA-PKcs;
Redox-sensitive signaling in inflammatory T cells and in autoimmune disease
Keywords: AMPK; AMP-activated protein kinase; AT; Ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATMIN; ATM Interactor; ATP; adenosine triphosphate; BSO; buthionine sulphoximine; DNA-PKcs; DNA-dependent protein kinase, catalytic subunit; NADPH; nicotina
RNA polymerase II pausing and transcriptional regulation of the HSP70 expression
Keywords: HSP; heat shock protein; HSF1; heat shock factor 1; Pol II; RNA polymerase II; UPR; unfolded protein response; HSE; heat shock element; P-TEFb; positive transcription elongation factor b; PARP; poly(ADP)-ribose polymerase; PAF1; polymerase associated fact
Expression of DNA damage response proteins in cervical cancer patients treated with radical chemoradiotherapy
Keywords: Cervical cancer; Chemoradiotherapy; ATM; PARP-1; DNA-PKcs;
Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity
Keywords: HCAR1; hydroxycarboxylic acid receptor 1; GPCR; G-protein coupled receptor; BRCA1; breast cancer type 1 susceptibility protein; NBS1; Nijmegen breakage syndrome 1; PRKDC; protein kinase DNA-activated catalytic polypeptide; DNA-PKcs; DNA-dependent protein
DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD)
Keywords: 9-1-1 complex; complex of Rad9 Rad1 and Hus1 proteins; A2E; N-retinylidene-N-retinylethanol-amine; AtRal; all-trans retinal; AMD; age-related macular degeneration; AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; ATM; ataxia-telangiectasia
Feedback autophagy activation as a key resistance factor of Ku-0060648 in colorectal cancer cells
Keywords: Colorectal cancer; Ku-0060648; Autophagy; DNA-PKcs; PI3K-AKT-mTOR;
Inhibiting DNA-PKCS radiosensitizes human osteosarcoma cells
Keywords: DNA-PK; DNA-PKcs; Osteosarcoma; Radiotherapy; Radiosensitizers; KU60648;
DNA-dependent protein kinase modulates the anti-cancer properties of silver nanoparticles in human cancer cells
Keywords: Silver nanoparticles; DNA damage; DNA repair; DNA-PKcs; JNK; Telomeres; Anti-cancer effects;
G2-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation
Keywords: RIBE; Carbon ion; Cell cycle; DNA-PKcs; ATM;
Lysines 3241 and 3260 of DNA-PKcs are important for genomic stability and radioresistance
Keywords: DNA double-strand breaks; Non-homologous end-joining; Acetylation; DNA-PKcs;
Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways
Keywords: PARP1; PARP2; H2AX; DNA-PKcs; Ku80; Double-strand breaks;
DNA-PKcs: A promising therapeutic target in human hepatocellular carcinoma?
Keywords: CHIP; chromatin immunoprecipitation; DNA-PKcs; DNA dependent protein kinase catalytic subunit; DSBs; double strand breaks; GI; genomic instability; HCC; hepatocellular carcinoma; NHEJ; non-homologous end-joining; Hepatocellular carcinoma; DNA repair; Sign
Original ArticleDNA-PKcs, a novel functional target of acriflavine, mediates acriflavine's p53-dependent synergistic anti-tumor efficiency with melphalan
Keywords: Acriflavine; Target identification; DNA-PKcs; Melphalan; p53;
Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics
Keywords: 53BP1; tumor suppressor p53 binding protein 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; Chk; checkpoint kinase; DSB; DNA double-strand break; DDR; DNA damage response; DNA-PKcs; DNA-dependent protein kinase, catalyt
mTORC1 and DNA-PKcs as novel molecular determinants of sensitivity to Chk1 inhibition
Keywords: Chk1; mTOR; DNA-PKcs; V158411; Double strand break repair;
An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy
Keywords: AA; Ascorbic acid; AEM1; ARE expression modulator 1; AEG1; Astrocyte elevated gene-1; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; APL; Acute promyelocytic leukemia; ARE; Antioxidant response element; ATO; Arsenic trioxide; Bach; BTB and CNC
DNA repair targeted therapy: The past or future of cancer treatment?
Keywords: DNA damage; DNA repair; Cancer; Radiation; Replication protein A; NER; nucleotide excision repair; MMR; DNA mismatch repair; BER; base excision repair; HDR; homology directed repair; FA; Fanconi anemia; HR; homologous recombination; DDR; DNA damage respon
BRCA1: Beyond double-strand break repair
Keywords: BRCA1; Base-excision repair; 8oxoG; 8-oxo-guanine; 8oxodG; 8-hydroxy-2â²-deoxyguanosine; AP; apurinic/apyrimidinic; APE1 (or APE1/REF1); AP-endonuclease (redox effector factor-1); ATR; ataxia telangiectasia and Rad3 related; ATM; ataxia telangiectasia mu
DNA-PKcs interference sensitizes colorectal cancer cells to a mTOR kinase inhibitor WAY-600
Keywords: Colorectal cancer; mTOR; WAY-600; DNA-PKcs; Chemo-sensitization;
DNA mismatch repair enzymes: Genetic defects and autoimmunity
Keywords: AA; aplastic anemia; ARS; aminoacyl tRNA synthetase; CMMR-D; constitutional mismatch repair-deficiency syndrome; DM; dermatomyositis; DM1; myotonic dystrophy type I; DNA-PKcs; DNA-dependent protein kinase; ELISA; enzyme-linked immunosorbent assay; HD; Hun
Lysine 271 but not lysine 210 of XRCC4 is required for the nuclear localization of XRCC4 and DNA ligase IV
Keywords: DNA double-strand break repair; Non-homologous end-joining; XRCC4; DNA ligase IV; Nuclear localization; DAPI; 4,6-diamidino-2-phenylindole dihydrochloride; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; D-PBS(â); Ca2+- and Mg2+-free Dulbecco'
ATR signaling cooperates with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam
Keywords: IR; ionizing radiation; LET; linear energy transfer; HRS; hyper-radiosensitivity; IRR; induced radioresistance; DSB; DNA double strand break; ATM; ataxia telangiectasia mutated homolog; ATR; ataxia telangiectasia and Rad3 related; DNA-PKcs; DNA-dependent
The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry
Keywords: DNA-PKcs; DNA-dependent protein kinase catalytic subunit; Plk1; polo-like kinase 1; PBD; polo box domain;
Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains
Keywords: APLF; aprataxin- and PNK-like factor; PNKP; polynucleotide kinase phosphatase; FHA; forkhead-associated; XRCC1; X-ray repair cross-complementing protein 1; XRCC4; X-ray repair cross-complementing protein 4; PARP-1; poly(ADP-ribose)polymerase 1; NHEJ; non-
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis
Keywords: DNA-dependent protein kinase; Non-homologous end joining; Mitosis; ATM; ataxia telangiectasia mutated; ATR; ATM- and Rad3-related; ds; double-stranded; cryo-EM; cryo-electron microscopy; DSB; DNA double strand break; DNA-PK; DNA-activated/dependent protei
Proteomics of dedifferentiation of SK-N-BE2 neuroblastoma cells
Keywords: Neuroblastoma; Dedifferentiation; Proteomics; DISC1; DNA-PKcs;
The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair
Keywords: APE1; apurinic/apyrimidinic endonuclease; A-T; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; BER; base excision repair; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DSB; DNA double-strand break; ECL; enhanced chemiluminescence; F
Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines
Keywords: DNR; daunorubicin; NHEJ; non-homologous end-joining; MDR; multidrug resistance; DSB; DNA-double-strand break; EMSA; electrophoresis mobility shift assay; ChIP; chromatin immunoprecipitation; Multidrug-resistant cell line; Daunorubicin; NHEJ; DNA-PKcs; DNA
Opportunities for translation: Targeting DNA repair pathways in pancreatic cancer
Keywords: ATR; ATM-Rad3-related; BER; base excision repair; Chk1; checkpoint kinase 1; DDR; DNA damage response and repair; DNA-PKcs; DNA-PK catalytic subunit; DOT1L; DOT1-like; DSB; double strand break; FOLFIRINOX; folinic acid, 5-FU, irinotecan, oxaliplatin; 5-FU
Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair
Keywords: DNA repair; DNA-PKcs; Ionizing radiation; DNA-PK deficiency; NU7441;
Functional overlaps between XLF and the ATM-dependent DNA double strand break response
Keywords: Cernunnos; ATM; DNA-PKcs; NHEJ; V(D)J recombination; 53BP1;
Interplay of DNA damage and cell cycle signaling at the level of human replication protein A
Keywords: AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; ATRIP; ATR-interacting protein; CDK; cyclin-dependent kinase; CIP; calf intestinal phosphatase; DDR; DNA damage response; DNA-PKcs; D
Reprint of “Functional overlaps between XLF and the ATM-dependent DNA double strand break response”
Keywords: Cernunnos; ATM; DNA-PKcs; NHEJ; V(D)J recombination; 53BP1;
Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway
Keywords: Wogonin; Reversal effect; MRP1; DNA-PKcs; Nrf2/AREWogonin (PubChem CID: 5281703); DMSO (PubChem CID: 679); DAPI (PubChem CID: 2954); MTT formazan(PubChem CID: 16218671); Adriamycin (PubChem CID: 31703); H2O2 (PubChem CID: 784); tBHQ (PubChem CID: 16043)
Distinct functions of steroidogenic factor-1 (NR5A1) in the nucleus and the centrosome
Keywords: CDK2; cyclin-dependent kinase 2; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; SF-1; Steroidogenic Factor 1 NR5A1, Ad4BP; SUMO; small ubiquitin like modifier; MT; microtubule; SF-1; Adrenal; Gonad; Centros
γH2AX foci formation in the absence of DNA damage: Mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway
Keywords: γH2AX; CHK2; DNA-PKcs; DNA damage; Mitosis;