دانلود مقالات ISI درباره Egfr + ترجمه فارسی

EGFR mediates LPA-induced proteolytic enzyme expression and ovarian cancer invasion: Inhibition by resveratrol

Keywords: Lysophosphatidic acid; EGFR; Ovarian cancer; Resveratrol; Invasion;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

CHFR aberrant methylation involves a subset of human lung adenocarcinoma associated with poor clinical outcomes

Keywords: Lung; Adenocarcinoma; CHFR; EGFR; EML4-ALK; KRAS; Hypermethylation; Mutation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Src kinases are important regulators of mitochondrial functions

Keywords: OXPHOS; oxidative phosphorylation; ETS; electron transport system; PKA; cAMP-dependent protein kinase; ROS; reactive oxygen species; Y; tyrosine; MEF; mouse embryonic fibroblasts; ER; endoplasmic reticulum; PKCδ; protein kinase C δ; RBM; rat brain mitoc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting epidermal growth factor receptor/human epidermal growth factor receptor 2 signalling pathway by a dual receptor tyrosine kinase inhibitor afatinib for radiosensitisation in murine bladder carcinoma

Keywords: Bladder cancer; Radiotherapy; Afatinib; EGFR; HER2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Exploring pyrimidine-substituted curcumin analogues: Design, synthesis and effects on EGFR signaling

Keywords: Apoptosis; Cell cycle; Colon cancer; Curcumin analogues; EGFR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Role of TRPM2 and TRPV1 cation channels in cellular responses to radiation-induced DNA damage

Keywords: ADPR; adenine 5′-diphosphoribose; 2-APB; 2-aminoethoxydiphenyl borate; ATM; ataxia telangiectasia mutated; 53BP1; tumor suppressor p53-binding protein 1; CAP; capsaicin; CPZ; capsazepine; DPQ; 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Involvement of connexin43 in the EGF/EGFR signalling during self-renewal and differentiation of neural progenitor cells

Keywords: bFGF; basic fibroblast growth factor; Cx(s); connexin(s); EdU; 5-ethynyl-2′-deoxyuridine; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; FRAP; fluorescence recovery after photobleaching; GJ(s); gap junction(s); GJIC; gap junctiona

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

A novel anticancer agent Broussoflavonol B downregulates estrogen receptor (ER)-α36 expression and inhibits growth of ER-negative breast cancer MDA-MB-231 cells

Keywords: ER-negative breast cancer; Breast cancer stem cells; Broussoflavonol B; ER-α36; EGFR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells

Keywords: SOX2; EGFR; Self-renewal; Prostate cancer stem cell;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

IC-4, a new irreversible EGFR inhibitor, exhibits prominent anti-tumor and anti-angiogenesis activities

Keywords: Irreversible TKI; EGFR; Angiogenesis; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor

Keywords: Bn; bombesin; EGFR; epidermal growth factor receptor; GI; gastrointestinal; GPCR; G protein coupled receptor; HNSCC; head and neck squamous cell cancers; MMP; matrix metalloproteinases; NETs; neuroendocrine tumors; NT; neurotensin; PETs; pancreatic endocr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Epidermal growth factor receptor transactivation by intracellular prostaglandin E2-activated prostaglandin E2 receptors. Role in retinoic acid receptor-β up-regulation

Keywords: iPGE2; intracellular prostaglandin E2; EPR; EP receptors; RARβ; retinoic acid receptor-β; HIF-1α; factor hypoxia-inducible factor-1α; VEGF-A; factor vascular endothelial growth factor-A; EGFR; epidermal growth factor receptor; ATRA; all-trans retinoic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Oxidative stress induced by P2X7 receptor stimulation in murine macrophages is mediated by c-Src/Pyk2 and ERK1/2

Keywords: P2X7R; P2X7 receptor channels; LPS; lipopolysaccharide; IL-1β; interleukin-1β; TNFα; tumor necrosis factor α; ROS; reactive oxygen species; JNK; c-Jun N-terminal kinase; ERK1/2; extracellular regulated kinases 1 and 2; MAPKs; mitogen-activated protein

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting colorectal cancer cells with single-walled carbon nanotubes conjugated to anticancer agent SN-38 and EGFR antibody

Keywords: Single-walled carbon nanotubes; SN38; C225; EGFR; Human carboxylesterase enzyme;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

RAB7 and TSG101 are required for the constitutive recycling of unliganded EGFRs via distinct mechanisms

Keywords: Control siRNA; siCON; Early Endosome Autoantigen 1; EEA1; Endosomal sorting complex required for transport; ESCRT; Epidermal Growth Factor; EGF; Epidermal Growth Factor Receptor; EGFR; Guanosine nucleotide binding protein; G-protein; Late endosome/multive

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Plant stanols induce intestinal tumor formation by up-regulating Wnt and EGFR signaling in ApcMin mice

Keywords: Akt; protein kinase B; Apc; adenomatous polyposis coli; EGFR; epidermal growth factor; ERK1/2; extracellular signal-regulated kinase 1/2; HMG-CoA; 3-hydroxy-3-methylglutaryl-CoA; LDL; low density lipoprotein; Min; multiple intestinal neoplasia; MNU; methy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Synergistic inhibition of cell migration by tetraspanin CD82 and gangliosides occurs via the EGFR or cMet-activated Pl3K/Akt signalling pathway

Keywords: GM3; Metastasis; EGFR; HGFR; Akt; CD82/KAI-1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Biomarker analysis in oesophagogastric cancer: Results from the REAL3 and TransMAGIC trials

Keywords: Adenocarcinoma; Biomarker; Chemotherapy; EGFR; Gastric; Oesophageal; Oesophagogastric; Palliative; Panitumumab; Peri-operative;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Intracerebroventricular administration of ouabain, a Na/K-ATPase inhibitor, activates mTOR signal pathways and protein translation in the rat frontal cortex

Keywords: 4E-BP; eukaryotic translation initiation factor 4E binding protein; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; DAPI; 4′,6′-diamidino-2-phenylindole; EGFR; epidermal growth factor recepto

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

EGFR tyrosine kinase inhibitory peptide attenuates Helicobacter pylori-mediated hyper-proliferation in AGS enteric epithelial cells

Keywords: Helicobacter pylori; Gastric epithelial cells; EGFR; β-Catenin; Peptide;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways

Keywords: DMEM; Dulbecco's modified Eagle's medium; DPBS; Dulbecco's phosphate buffered saline; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; ER; estrogen receptor; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The NFL-TBS.40-63 anti-glioblastoma peptide enters selectively in glioma cells by endocytosis

Keywords: Antp; antennapedia-homeodomain-derived antennapedia; ATP; adenosine triphosphate; BSA; bovine serum albumin; chlorpr.; chlorpromazine hydrochloride; CPP; cell penetrating peptide; cytoch. D; cytochalasin D; DAPI; 4′,6′-diamidino-2-phenylindole; DMA; 5

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of angiogenesis and invasion by DMBT is mediated by downregulation of VEGF and MMP-9 through Akt pathway in MDA-MB-231 breast cancer cells

Keywords: bFGF; basic fibroblast growth factor; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfoxide; ECM; extracellular matrix; EDTA; ethylenediamine tetraacetic acid; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Estrogen defines the dynamics and destination of transactivated EGF receptor in breast cancer cells: Role of S1P3 receptor and Cdc42

Keywords: Breast cancer; Estrogen; Sphingosine-1-phosphate; EGFR; Cdc42;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species

Keywords: ALK; activin-like kinase; α-SMA; α-smooth muscle actin; BMP; bone morphogenic protein; CDK; chronic kidney disease; CTGF; connective tissue growth factor; DAB; 3,3′-diaminobenzidine; DPI; diphenyleneiodonium chloride; ECM; extracellular matrix; EGF; e

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

The radio-sensitizing effect of xanthohumol is mediated by STAT3 and EGFR suppression in doxorubicin-resistant MCF-7 human breast cancer cells

Keywords: Xanthohumol; Flavonoid; Radio-sensitizer; Cancer cell cross-resistance; STAT3; EGFR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Evidence of securin-mediated resistance to gefitinib-induced apoptosis in human cancer cells

Keywords: EGFR; epidermal growth factor receptor; EGF; epidermal growth factor; PTTG; pituitary-tumor transforming gene; DMSO; dimethyl sulfoxide; PI; propidium iodide; MTT; 3-(4,5-dimethyl-thiazol-2-yl) 2,5-diphenyl tetrazolium bromide; DiOC6; 3,3′-dihexiloxadic

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Determinants of Survival in Advanced Non-Small-Cell Lung Cancer in the Era of Targeted Therapies

Keywords: EGFR; KRAS; Non-small-cell lung cancer; Prognosis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Transcriptomic profiling of progesterone in the male fathead minnow (Pimephales promelas) testis

Keywords: 11-KT; 11-ketotestosterone; AKT1; RAC-α serine/threonine-protein kinase; APOE; apolipoprotein E; APP; amyloid β (A4) precursor protein; AR; androgen receptor; BCL2L1; BCL2-like 1; BCL6; B-cell CLL/lymphoma 6; BMP2; bone morphogenetic protein 2; BMP4; bo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Endogenous CNTF mediates stroke-induced adult CNS neurogenesis in mice

Keywords: BDNF; brain-derived neurotrophic factor; BrdU; 5-bromo-2′-deoxyuridine; CC; corpus callosum; CD45; cluster of differentiation number 45 or leukocyte common antigen; CNTF; ciliary neurotrophic factor; Dll3; delta-like 3; ECA; external carotid artery; EGF

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Hepatocytes display a compensatory survival response against cadmium toxicity by a mechanism mediated by EGFR and Src

Keywords: Cadmium; NADPH oxidase; ROS; Stat3; Src; EGFR; Erk; Metallothionein;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Identification and characterization of bi-thiazole-2,2′-diamines as kinase inhibitory scaffolds

Keywords: MAPK; mitogen-activated protein kinase; JD; JNK Docking; ERK; extracellular signal signal-regulated kinase; JNK; c-Jun N-terminal kinase; MKK; MAPK kinase; GST; glutathione S-transferase; GSH; glutathione; JIP; JNK-interacting protein; DCX; doublecortin X

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Sustained EKR inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy

Keywords: EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; MTT; 1-(4,5-Dimethylthiazol-2-yl)-3,5-diphenylformazan; PDT; photodynamic therapy; TKI; tyrosine kinase inhibitor; mAb; monoclonal antibody; TPPS2a; meso-tetraphenylporphi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The three α1-adrenoceptor subtypes show different spatio-temporal mechanisms of internalization and ERK1/2 phosphorylation

Keywords: α1-AR; α1 adrenoceptor; β2-AR; β2 adrenoceptor; AT1AR; angiotensin receptor type 1A; Bmax; maximum number of binding sites; BSA; bovine serum albumin; ConA; concanavalin A; DMSO; dimethyl sulfoxide; EGFR; epidermal growth factor receptor; GAPDH; glyce

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

The Usp8 deubiquitination enzyme is post-translationally modified by tyrosine and serine phosphorylation

Keywords: Usp8; Ubiquitination; Deubiquitination; EGFR; Tyrosine phosphorylation; Serine phosphorylation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Efficacy and mechanism of action of Proellex, an antiprogestin in aromatase overexpressing and Letrozole resistant T47D breast cancer cells

Keywords: ER; estrogen receptor; PR; progesterone receptor; PR-A and PR-B; progesterone receptor isoform-A and B; AI; aromatase inhibitors; P450 CYP; cytochrome P450 family, hemprotein catalyze oxidation; CY19A1; aromatase gene; T47Dcon T47D; breast cancer cells st

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Low electric fields induce ligand-independent activation of EGF receptor and ERK via electrochemical elevation of H+ and ROS concentrations

Keywords: EF(s); Electric field(s); LEF; Low electric fields; ROS; Reactive oxygen species; H2DCF-DA; Dichlorodihydrofluorescein diacetate; DHA; Dehydroascorbic acid; RTK; Receptor tyrosine kinase; PTPs; Protein tyrosine phosphatases; DC; Direct current; FITC; Fluo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

p300/CBP dependent hyperacetylation of histone potentiates anticancer activity of gefitinib nanoparticles

Keywords: Gefitinib; EGFR; T790M; Histone; p300/CBP;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Nox4 and diabetic nephropathy: With a friend like this, who needs enemies?

Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; AA; arachidonic acid; AGE; advanced glycation end-product; Akt/PKB; Akt/protein kinase B; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; AOPP; advanced oxidation protein product; AT1; angiotensin II t

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

The COOH-terminus of TM4SF5 in hepatoma cell lines regulates c-Src to form invasive protrusions via EGFR Tyr845 phosphorylation

Keywords: ICL; intracellular loop; SYF; c-Src-, Fyn-, and Yes-negative mouse embryonic fibroblasts; SYF++; c-Src-reconstituted SYF cells; SFKs; c-Src family kinases; TERM; tetraspanin-enriched microdomain; TM4SF5; Transmembrane 4 L6 family member 5; TM4SF5ΔC; COOH

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors

Keywords: GLTKDEDQGKWYDZ-PZLHFWPISA-N; IDEGBQKYWCBOER-APBAZZLNSA-N; JCLMWQYPEXFXGC-GELLHEPZSA-N; BNSPSDNPTLGBKM-KVIZONTOSA-N; EGFR; 5-Ethynylpyrimidine; 4-Anilino-3-cyano-5-phenylpyridine; m-Amino-N-phenylbenzamide; Tyrosine kinase inhibitors;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

Keywords: Cancer-Associated Fibroblasts; Distal Cholangiocarcinoma; Intrahepatic Cholangiocarcinoma; Molecular Pathogenesis; α-SMA; α-smooth muscle actin; CA19-9; carbohydrate antigen 19-9; CAF; cancer-associated fibroblast; CCA; cholangiocarcinoma; CT; computed

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Sweet-Heart - An integrated suite of enabling computational tools for automated MS2/MS3 sequencing and identification of glycopeptides

Keywords: CID; collision induced dissociation; DDA; data dependent acquisition; ETD; electron transfer dissociation; Q/TOF; quadrupole/time-of-flight; NeuGc; N-glycolyl neuraminic acid; Site-specific glycosylation; Glycoproteomics; Automated glycopeptide identifica

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

E-type prostanoid receptor 4 (EP4) in disease and therapy

Keywords: AMPK; AMP-activated protein kinase; cAMP; cyclic adenylyl monophosphate; CFTR; cystic fibrosis transmembrane conductance regulator; ClC; chloride channel; COX; cyclooxygenase; CREB; cAMP-response element-binding protein; DP; D-type prostanoid receptor; DS

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Original ResearchFull Report: Basic and Translational-LiverMUC15 Inhibits Dimerization of EGFR and PI3K-AKT Signaling and Is Associated With Aggressive Hepatocellular Carcinomas in Patients

Keywords: Liver Cancer; Prognostic Factor; Mechanism; Mouse Model; AKT; v-akt murine thymoma viraloncogene homolog; EGFR; epidermal growth factor receptor; EMT; epithelial−mesenchymal transition; ERK; extracellular regulated kinase; GFP; green fluorescent protein

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2013 سفارش ترجمه

Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks

Keywords: ARF; ADP-ribosylation factor; DAG; diacylglycerol; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; FAPP2; Four-phosphate adaptor protein 2; FAAT motif; two phenylalanines in an acidic tract motif; GPCR; G-p

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2013 سفارش ترجمه

Recent advances on the beneficial use and health implications of Pu-Erh tea

Keywords: AGE; Advanced glycation end products; AFB1; Aflatoxin B1; ALT; Alanine aminotransferase; ANOVA; Analysis of variance; AST; Aspartate amino-transferase; BMI; Body mass index; BW; Body weight; CCl4; Carbon tetrachloride; CVD; Cardiovascular disease; CHO; Ch

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2013 سفارش ترجمه

Optimal use of blood tests in acute medicine

Keywords: CRP; d-Dimer; eGFR; point of care systems; predictive values; sensitivity; specificity; test performance; troponin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Discordance of KRAS Mutational Status in a Single Colonic Resection Specimen in a Patient With Colorectal Cancer: A Case Report and Review of the Literature

Keywords: Colorectal cancer; Discordance; KRAS; Mutational status; EGFR;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Family history of lung cancer in never smokers with non-small-cell lung cancer and its association with tumors harboring EGFR mutations

Keywords: Lung cancer; Non-small-cell lung cancer; Family history; Never smokers; Epidermal growth factor receptor; EGFR; Anaplastic lymphoma kinase; ALK; KRAS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه