EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival
Keywords: EGFR; Chloroquine; Autophagy; Irradiation;
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EGFR cooperates with glucose transporter SGLT1 to enable chromatin remodeling in response to ionizing radiation
Keywords: SGLT; EGFR; Ionizing radiation; Glucose uptake; ATP crisis;
Hyperuricemia is Associated with Hypertension, Obesity, and Albuminuria in Children with Chronic Kidney Disease
Keywords: BMI; Body mass index; BP; Blood pressure; CKD; Chronic kidney disease; eGFR; Estimated glomerular filtration rate; FEU; Fractional excretion of filtered urate; GFR; Glomerular filtration rate; RR; Relative risk; SBP; Systolic blood pressure;
TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities
Keywords: TGF-β; NOX; NADPH oxidases; PAI-1; ROS; p53; EGFR; SMADs;
miRNA-7-5p inhibits melanoma cell migration and invasion
Keywords: miRNA; microRNA; IRS-2; insulin receptor substrate-2; IRS-1; insulin receptor substrate-1; PI3K; phosphatidylinositol 3-kinase; Akt; protein kinase B; RT-qPCR; reverse transcription and quantitative polymerase chain reaction; BRAF; v-Raf murine sarcoma vi
Clinical and Molecular Spectrum of Renal Malformations in Kabuki Syndrome
Keywords: eGFR; Estimated glomerular filtration rate; KS; Kabuki syndrome; US; Ultrasound;
Renal involvement in a patient with cobalamin A type (cblA) methylmalonic aciduria: A 42-year follow-up
Keywords: AdoCbl; adenosylcobalamin; cblA; methylmalonic aciduria cblA type OMIM 251100; cblB; methylmalonic aciduria cblB type OMIM 251110; cblD-variant 2; methylmalonic aciduria and homocystinuria cblD type OMIM 277410; CKD; chronic kidney disease; eGFR; estimate
Renal transplantation in 4 patients with methylmalonic aciduria: A cell therapy for metabolic disease
Keywords: MMA; methylmalonic aciduria; CKD; chronic kidney disease; eGFR; glomerular filtration rate; MRI; magnetic resonance imaging; DQ; development quotient; IQ; intellectual quotient; Methylmalonic acidemia; Chronic renal disease; Renal transplantation;
Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitors
Keywords: EGFR; Irreversible inhibitors; Active transport; A549 cell line; HPLC-MS/MS;
Estimated GFR reporting is associated with decreased nonsteroidal anti-inflammatory drug prescribing and increased renal function
Keywords: eGFR; NSAIDs; prescribing rate; renal function;
Large noncoding RNA HOTAIR enhances aggressive biological behavior and is associated with short disease-free survival in human non-small cell lung cancer
Keywords: cDNA; complementary DNA; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; DMEM; Dulbecco's modified Eagle's medium; EV cells; empty vector transfected cells; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; H3K27; histon
Highly sensitive and noninvasive detection of epidermal growth factor receptor T790M mutation in non-small cell lung cancer
Keywords: EGFR; Epidermal growth factor receptor; NSCLC; Non-small cell lung cancer; RFLP; Restriction fragment length polymorphism; Scorpions ARMS; Scorpion amplified refractory mutation system; TKIs; Tyrosine kinase inhibitors; Epidermal growth factor receptor; T
Association of single nucleotide polymorphisms of β2-adrenergic receptor gene with clinicopathological features of pancreatic carcinoma
Keywords: Pancreatic carcinoma; β2-Adrenoceptor; Single nucleotide polymorphism; Prognosis; EGFR; VEGF; MMP-2;
Direct interaction between surface β1,4-galactosyltransferase 1 and epidermal growth factor receptor (EGFR) inhibits EGFR activation in hepatocellular carcinoma
Keywords: β1,4GT1; EGFR; Interaction; Dimerization; Phosphorylation;
Differential anti-tumor activities of curcumin against Ras- and Src-activated human adenocarcinoma cells
Keywords: 4E-BP1; eukaryotic initiation factor 4-binding protein 1; Cdk1; cyclin-dependent kinase 1; EGFR; epidermal growth factor receptor; FACS; fluorescence activated cell sorting; IC50; 50% inhibitory concentration; MAPK; mitogen-activated protein kinase; mTOR;
Nucleotide-binding oligomerization domain containing 2: Structure, function, and diseases
Keywords: CARD; caspase recruitment domain; CARD15; caspase recruitment domain 15; DM; diabetes mellitus; EGFR; epidermal growth factor receptor; FMF; familial Mediterranean fever; GPA; granulomatous polyangiitis; GVHD; graft-versus-host disease; IBD; inflammatory
Gambogic acid induces EGFR degradation and Akt/mTORC1 inhibition through AMPK dependent-LRIG1 upregulation in cultured U87 glioma cells
Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; EGFR; epidermal growth factor receptor; LRIG1; leucine-rich repeat and Ig-like domain-containing-1; GB; gambogic acid; mTORC1; mammalian target of rapamycin (mTOR) complex 1; Gambogic acid;
Flagellin/Toll-like receptor 5 response was specifically attenuated by keratan sulfate disaccharide via decreased EGFR phosphorylation in normal human bronchial epithelial cells
Keywords: #COPD; chronic obstructive pulmonary disease; TLRs; Toll-like receptors; GAG; glycosaminoglycans; NHBE; normal human bronchial epithelial; KS; keratan sulfate; HA; hyaluronan; CS; chondroitin sulfate; MMP; matrix metalloprotease; LPS; lipopolysaccharide;
Ubiquitination and degradation of the hominoid-specific oncoprotein TBC1D3 is regulated by protein palmitoylation
Keywords: GAP; GTPase activating protein; EGFR; epidermal growth factor receptor; IR; insulin receptor; EGF; epidermal growth factor; IGF-1; insulin-like growth factor1; FCS; fetal calf serum; PP2A; protein phosphatase 2A; IRS-1; insulin receptor substrate1; Fbw8;
Expression and purification of chimeric peptide comprising EGFR B-cell epitope and measles virus fusion protein T-cell epitope in Escherichia coli
Keywords: EGFR; B-cell epitope; Chimeric peptide; Expression; Purification;
Expression of EGFR and HPV-associated p16 in oropharyngeal carcinoma: Correlation and influence on prognosis after radiotherapy in the randomized DAHANCA 5 and 7 trials
Keywords: EGFR; HPV; p16; HNSCC; Radiotherapy;
Renal function and bone mineral density in community-dwelling elderly Japanese men: The Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study
Keywords: BMD; bone mineral density; BMI; body mass index; Cr; creatinine; CTX; cross-linked carboxy-terminal telopeptide of type I collagen; CV; coefficient of variation; DXA; dual X-ray absorptiometry; eCCr; estimated creatinine clearance; eGFR; estimated glomeru
Serum phosphate and hip bone mineral density as additional factors for high vascular calcification scores in a community-dwelling: The São Paulo Ageing & Health Study (SPAH)
Keywords: OPG; osteoprotegerin; RANK; receptor activator of nuclear factor kappa B; RANKL; receptor activator of nuclear factor kappa B ligand; BMP; bone morphogenetic proteins; MGP; matrix Gla protein; Runx-2; runt-related transcription factor 2; BMD; bone mineral
Genetic variations in EGFR and ERBB4 increase susceptibility to cervical cancer
Keywords: EGFR; ERBB4; Cervical cancer; Polymorphism; Transmission disequilibrium test;
Circulating TNF receptor 2 is associated with the development of chronic kidney disease in non-obese Japanese patients with type 2 diabetes
Keywords: BMI; body mass index; eGFR; estimated GFR; GFR; glomerular filtration rate; HMW; high molecular weight; hsCRP; high sensitive C-reactive protein; TNF; tumor necrosis factor; sTNF-R; soluble TNF receptor; eGFR; Tumor necrosis factor; Type 2 diabetes;
Usefulness of R.E.N.A.L. Nephrometry Scoring System for Predicting Outcomes and Complications of Percutaneous Ablation of 751 Renal Tumors
Keywords: kidney; carcinoma, renal cell; cryosurgery; catheter ablation; forecasting; CT; computerized tomography; eGFR; estimated glomerular filtration rate; MRI; magnetic resonance imaging; RCC; renal cell carcinoma; RFA; radio frequency ablation;
Regular ArticleCystatin C and creatinine as markers of bleeding complications, cardiovascular events and mortality during oral anticoagulant treatment
Keywords: CRP; C-reactive protein; eGFR; calculated glomerular filtration rate; HR; hazard ratio; CI; confidence interval; INR; international normalized ratio; VKA; vitamin K antagonist; CV; coefficient of variance; Anticoagulation; Cystatin C; Kidney function; Ble
Increased comorbidities in heart failure patients ⥠85 years but declined from > 90 years: Data from the Swedish Heart Failure Registry
Keywords: ACEi; ACE inhibitors; BNP; B-type natriuretic peptide; BB; Beta blockers; eGFR; Estimated glomerular filtration rate; HF; Heart failure; HFNEF; Heart failure with normal left ventricular ejection fraction; LVEF; Left ventricular ejection fraction; NT-proB
Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes
Keywords: AE; anion exchanger; AMPK; AMP-activated protein kinase; CA; carbonic anhydrase; CTS; cardiotonic steroids; DAB; 1,4-dideoxy-1,4-imino-d-arabinitol; DIDS; 4,4â²-diisothiocyanostilbene-2,2â²-disulfonic acid; EGFR; epidermal growth factor receptor; ERK; e
Electrochemical impedance immunosensor based on gold nanoparticles-protein G for the detection of cancer marker epidermal growth factor receptor in human plasma and brain tissue
Keywords: EGFR; Cancer biomarker; Protein G; Label-free biosensor; Gold nanoparticles; Plasma;
Interaction of EGFR with the tumour microenvironment: Implications for radiation treatment
Keywords: EGFR; Radiotherapy; Microenvironment;
Adequacy of CT-guided biopsies with histomolecular subtyping of pulmonary adenocarcinomas: Influence of ATS/ERS/IASLC guidelines
Keywords: TTNB; Trans-Thoracic Needle core Biopsy; ALK; Anaplastic Lymphoma Kinase; FISH; Fluorescent In Situ Hybridization; CISH; Chromogenic In Situ Hybridization; EGFR; Epidermal Growth Factor Receptor; TKI; Tyrosine Kinase Inhibitor; FNA; Fine Needle Aspiration
Genetic deletion of the EGFR ligand epigen does not affect mouse embryonic development and tissue homeostasis
Keywords: EGFR; Epigen; Gene targeting; Knockout mouse;
Human chorionic gonadotropin (hCG) induces MAPK3/1 phosphorylation in the zebrafish ovarian follicle cells independent of EGF/EGFR pathway
Keywords: hCG; EGFR; MAPK3/1; Ovary; Zebrafish;
p21-activated kinases and gastrointestinal cancer
Keywords: AID; auto-inhibitory domain; CDK5RAP3; CDK5 kinase regulatory subunit-associated protein 3; CRC; colorectal carcinoma; EGFR; epithelial growth factor receptor; GAP; GTPase-activating protein; HBV; hepatitis B virus; HBx; HBV X protein; HCC; hepatocellular
Effect of siRNAs targeting the EGFR T790M mutation in a non-small cell lung cancer cell line resistant to EGFR tyrosine kinase inhibitors and combination with various agents
Keywords: T790M; EGFR; Non-small cell lung cancer; RNA interference; Afatinib; Cetuximab;
Impact of Periprocedural Bleeding on Incidence of Contrast-Induced Acute Kidney Injury in Patients Treated With Percutaneous Coronary Intervention
Keywords: bleeding; contrast-induced acute kidney injury; ACS; acute coronary syndromes; ANOVA; analysis of variance; CI-AKI; contrast-induced acute kidney injury; CKD; chronic kidney disease; Cr; creatinine; DBP; diastolic blood pressure; eGFR; estimated glomerula
Efficacy of cetuximab and panitumumab in oral squamous cell carcinoma cell lines: Prognostic value of MAGE-A subgroups for treatment success
Keywords: MAGE-A; Tumour antigen; Cetuximab; Panitumumab; EGFR;
“Trifecta” in Partial Nephrectomy
Keywords: kidney; carcinoma, renal cell; nephrectomy; laparoscopy; robotics; AKI; acute kidney injury; eGFR; estimated glomerular filtration rate; LPN; laparoscopic PN; MDRD; Modification of Diet in Renal Disease; PN; partial nephrectomy; RPN; robot-assisted PN; WI
Expression of hepatocyte epidermal growth factor receptor, FAS and glypican 3 in EpCAM-positive regenerative clusters of hepatocytes, cholangiocytes, and progenitor cells in human liver failure
Keywords: Regenerative clusters; MET; EGFR; FAS; Glypican 3; Fulminant Hepatitis;
Differential response to 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) in non-small cell lung cancer cells with distinct oncogene mutations
Keywords: Non-small cell lung cancer; Vitamin D receptor; 1,25-Dihydroxyvitamin D3; Epidermal growth factor receptor; K-ras; CSS; charcoal-stripped serum; DMSO; dimethylsulfoxide; EGFR; epidermal growth factor receptor; FBS; fetal bovine serum; 1,25(OH)2D3; 1,25-di
Cross-talk between GPER and growth factor signaling
Keywords: GPR30/GPER; Growth factor signaling; EGFR; IGF-IR; Estrogen; Cancer;
Cystatin C is independently associated with total and cardiovascular mortality in individuals undergoing coronary angiography. The Ludwigshafen Risk and Cardiovascular Health (LURIC) study
Keywords: Cystatin C; Renal function; eGFR; Mortality; Coronary artery disease;
Research ArticleClinical milestones for the prediction of severe anemia by chronic hepatitis C patients receiving telaprevir-based triple therapy
Keywords: HCV; hepatitis C virus; PegIFN; pegylated interferon; RBV; ribavirin; SVR; sustained virological response; TVR; telaprevir; ITPA; inosine triphosphatase; SNP; single nucleotide polymorphism; Hb; hemoglobin; eGFR; estimated glomerular filtration rate; RVR;
HER2 regulates Brk/PTK6 stability via upregulating calpastatin, an inhibitor of calpain
Keywords: ALLN; N-acetyl-leucyl-leucyl-norleucinal; Brk; breast tumor kinase; CHX; cycloheximide; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; Erk; extracellular signal-regulated kinase; FAK;
Abamectin resistance in Drosophila is related to increased expression of P-glycoprotein via the dEGFR and dAkt pathways
Keywords: Avermectin; Resistance; Drosophila; EGFR; Akt;
LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2
Keywords: EGFR; Epidermal growth factor receptor; GBM; glioblastoma multiforme; RNAi RNA interference; LRIG1; , leucine-rich repeats and immunoglobulin-like domains 1; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; TMZ; temozolomide; Topo
Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome
Keywords: EGFR; PTEN; PIK3CA; KRAS; NRAS; BRAF; Esophagus adenocarcinoma;
Driver mutations among never smoking female lung cancer tissues in China identify unique EGFR and KRAS mutation pattern associated with household coal burning
Keywords: EGFR; KRAS; Lung cancer; Never smoking; China; Driver mutations;
Structural landscape of the proline-rich domain of Sos1 nucleotide exchange factor
Keywords: Abi1; Abl interactor 1; CD; Circular dichroism; Cdc25; Cell cycle division 25; DH; Dbl homology; DLS; Dynamic light scattering; EGFR; Epidermal growth factor receptor; Eps8; EGFR kinase substrate 8; Grb2; Growth factor receptor binder 2; GuHCl; Guanidine