The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE2- and retaining PGE1-mediated signaling in live cells
Keywords: G-پروتئین گیرنده های متصل شده; EP selectivity; G protein-coupled receptor (GPCR); Prostaglandin; Prostaglandin E1; Prostaglandin E2; Receptor regulation; AA; arachidonic acid; COX-1 and -2; cyclooxygenase-1 and -2, respectively; cPGES; cytosolic PGES; DGLA; dihomo-γ-linolenic acid; EP