دانلود مقالات ISI درباره Grk + ترجمه فارسی

نوکلئوتید خارج سلولی باعث افزایش قدرت آگونیست در گیرنده هورمون 1 پاراتیروئید می شود

Extracellular nucleotides enhance agonist potency at the parathyroid hormone 1 receptor

Keywords: AMP-PNP; adenosine 5′- (β,γ-imido)triphosphate; BSA; bovine albumin; [Ca2+]i; cytosolic free Ca2+ concentration; cAMP; adenosine cyclic 3′,5′-monophosphate; CMP; cytidine 5′-monophosphate; CREB; cAMP response element binding protein; DMEM; Dulbe

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

پیشرفت در درک مکانیسم های اثرات جانبی ناشی از داروهای مهارکننده مخدر و افسردگی تنفسی

Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression

Keywords: Opioids; Analgesia; Adverse effects; Mechanisms; Constipation; Nausea; Vomiting; Respiratory depression; 5-HT; 5-hydroxytryptamine; 7TMRs; 7-transmembrane spanning G-protein coupled receptors; AC; adenylyl cyclase; β-arr1; β-arrestin1; β-arr2; β-arres

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2018 سفارش ترجمه

قاچاق گیرنده متابوتروپ گلوتامات

Metabotropic glutamate receptor trafficking

Keywords: AC; adenylate cyclase; Actn4; α-Actinin-4; ARF6; ADP-ribosylation factor 6; ATD; amino terminal domain; CAIN; calcineurin inhibitor protein; CaM; calmodulin; CaMKII; Ca2+/calmodulin-dependent protein kinase II; Cbln1; cerebellin 1 precursor; CC; coiled-c

دانلود رایگان متن کامل مقاله ISI 83 صفحه سال انتشار : 2018 سفارش ترجمه

مسیر سیگنال مه: بینش برای سیگنال در مورفوژنز

The Fog signaling pathway: Insights into signaling in morphogenesis

Keywords: Fog; Folded gastrulation; TF; transcription factor; GPCR; G-protein coupled receptor; Mist; mesoderm invagination signal transducer; Cta; Concertina; RhoGEF; Rho guanine nucleotide exchange factor; Rok; Rho kinase; PMG; posterior midgut; GBE; germ band ex

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

قاچاق محرک گیرنده توسط لیگاند

Ligand-directed trafficking of receptor stimulus

Keywords: AC; adenylate cyclase; β-AR; β-adrenergic receptor; CaM; calmoduline; cAMP; cyclic adenosine monophosphate; CHO; Chinese hamster ovary; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; DAG; diacylglycerol; DR; dopamine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

یک پلت فرم گیرنده انسولین جدید و ارتباط آن با مقاومت به انسولین و دیابت نوع 2

A novel insulin receptor-signaling platform and its link to insulin resistance and type 2 diabetes

Keywords: IR; insulin receptor; IRS1; insulin receptor substrate-1; IGF-R; insulin growth factor receptor; EGF; epidermal growth factor; MMP; matrix metalloproteinase; RTK; receptor tyrosine kinase; NGF; nerve growth factor; Neu1; mammalian neuraminidase-1; 4-MUNAN

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

میزان فسفوریلاسیون مختلف در رنگدانه های بینابینی مخروطی مهره دار با حساسیت طیفی مختلف

Different phosphorylation rates among vertebrate cone visual pigments with different spectral sensitivities

Keywords: λmax; absorption maximum wavelength; GRK; G protein-coupled receptor kinase; UV; ultraviolet; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; PC; l-α-phosphatidylcholine; Pi; inorganic phosphate; Cone visual pigment; Phosphorylation; G

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

تشدید سریع از گیرنده های فوتونی میله ای که بیان کننده خودمحوری بودن آرتستین-1 جهش یافته است

Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant

Keywords: GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; WT; wild type; Rh; dark unphosphorylated rhodopsin; Rh*; light-activated unphosphorylated rhodopsin; P-Rh; dark phosphorylated rhodopsin; P-Rh*; light-activated phosphorylated rhodo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

گیرنده های سطحی سلول های نوتروفیل و مسیرهای انتقال سیگنال داخل سلولی آنها

Neutrophil cell surface receptors and their intracellular signal transduction pathways

Keywords: Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

β3-adrenergic receptor activation induces TGFβ1 expression in cardiomyocytes via the PKG/JNK/c-Jun pathway

Keywords: β3-adrenergic receptor; Transforming growth factor β1; Protein kinase G; c-Jun N-Terminal kinase; c-Jun; Cardiomyocyte; AP-1; activator protein 1; β-AR; β-adrenergic receptor; cGMP; cyclic guanosine monophosphate; GRK; G protein-coupled receptor kinas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

G protein-coupled receptor kinases: Past, present and future

Keywords: αN-helix; N-terminal α-helical domain; α2AAR; α2A-adrenergic receptor; AST; active site tether; βAR; β-adrenergic receptor; β2AR; β2-adrenergic receptor; βARK; β-adrenergic receptor kinase; CLBD; C-terminal lipid binding domain; EM; electron mic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Designer Approaches for G Protein-Coupled Receptor Modulation for Cardiovascular Disease

Keywords: biased ligands; G protein-coupled receptor kinases; G protein-coupled receptors; AR; adrenergic receptor; AT1R; angiotensin II type 1A receptor; CRF; corticotropin-releasing factor; EGFR; epidermal growth factor receptor; ERK1/2; extracellular signal-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Bifunctional ligands of the bradykinin B2 and B1 receptors: An exercise in peptide hormone plasticity

Keywords: ACE; angiotensin converting enzyme; ε-ACA; ε-aminocaprolyl; APEX2; engineered soya bean peroxidase; Arg-CP; arginine carboxypeptidase; B1R; B1 receptor; B2R; B2 receptor; B2R-GFP; rabbit B2 receptor fused to green fluorescent protein; BK; bradykinin; CF

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

β-Adrenergic Receptor Trafficking, Degradation, and Cell Surface Expression Are Altered in Dermal Fibroblasts from Hypertrophic Scars

Keywords: β-AR; adrenergic receptor; HSF; hypertrophic scar fibroblast; GRK; GPCR kinase; NSF; non-scar fibroblast; NF; normal fibroblast; PKA; protein kinase A;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Different mode of arrestin-3 binding at the human Y1 and Y2 receptor

Keywords: ANOVA; analysis of variance; arr; arrestin; BRET; bioluminescence resonance energy transfer; EYFP; enhanced yellow fluorescent protein; FLR; finger loop region; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; YxR; neuropeptide Yx

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way

Keywords: Ad-GRK2; adenovirus expressing GPCR kinase-2; CD; contact dermatitis; CQ; chloroquine; DNCB; dinitrochlorobenzene; Gln; l-glutamine; GRK; GPCR kinase; MKP-1; MAPK phosphatase-1; siRNA; small interfering RNA;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Different phosphorylation patterns regulate α1D-adrenoceptor signaling and desensitization

Keywords: α1D-AR; α1D-adrenergic receptor; ERK; extracellular signal-regulated kinase; NA; noradrenaline; PMA; phorbol 12-myristate, 13-acetate; PKC; protein kinase C; GPCR; G protein-coupled receptor; GRK; GPCR kinase; IL3; intracellular loop 3; Ctail; carboxyl

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling

Keywords: βARs; β-adrenergic receptors; β-blockers; β-adrenergic receptor antagonists; β-miRs; β-adrenergic receptor/β-arrestin-regulated miRs; Carv; carvedilol; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; KO; knockout; MiRNAs o

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

AGC kinases, mechanisms of regulation ‎and innovative drug development

Keywords: AGC kinase; group of kinases related to PKA PKG and PKC; PKA; protein kinase A; PKC; protein kinase C; PKG; protein kinase G; PRK; protein kinase C related kinase (also termed PKN protein kinase N); PDK1; 3-phosphoinositide-dependent protein kinase 1; PKB

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase

Keywords: ARRB; β-arrestin; β2AR; β2-adrenergic receptor; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; LOF; loss-of-function; αMSH; α melanocyte-stimulating hormone; MCR; melanocortin receptor; MC1R; melanocortin 1 receptor; MGRN1;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

The G protein-coupled receptors deorphanization landscape

Keywords: GPCRs; G protein-coupled receptors; GRK; GPCR kinase; IUPHAR; International Union of Basic and Clinical Pharmacology; BPS; British Pharmacological Society; CTR; Calcitonin receptor; CLR; CT Receptor-like; RAMP; Receptor Activity-Modifying Proteins; β2AR;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of paroxetine on proximal β-adrenergic receptor signaling

Keywords: βAR; β-adrenergic receptor; βarr; β-arrestin; EC50; half-maximal effective concentration; FRET; fluorescence resonance energy transfer; GRK; G protein-coupled receptor; IC50; half-maximal inhibitory concentration; ISO; isoproterenol; mCFP; monomeric c

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

C-terminal motif of human neuropeptide Y4 receptor determines internalization and arrestin recruitment

Keywords: ANOVA; analysis of variance; arr; arrestin; BRET; bioluminescence resonance energy transfer; EYFP; enhanced yellow fluorescent protein; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; hPP; human pancreatic polypeptide; hY1R; huma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Pathophysiological consequences of receptor mistraffic: Tales from the platelet P2Y12 receptor

Keywords: ADP; Adenosine diphosphate; CNM; centronuclear myopathy; CMT; Charcot-Marie- Tooth; CAMs; constitutively active mutants; GAPP; Genotyping and Phenotyping of Platelets consortium; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Matrix Signaling Subsequent to a Myocardial Infarction

Keywords: βAR signaling; chronic ischemic cardiomyopathy; matrix signaling; myocardial infarction; tissue factor-bearing microparticles; Yucatan mini swine; ADRB1; β1-adrenergic receptor; ADRB2; β2-adrenergic receptor; AR; adrenergic receptor; ARRB1; β1-arresti

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Keywords: ADP; adenosine 5′-diphosphate; AgRP; agouti-related peptide; AMPK; 5′-AMP-activated protein kinase; ApnA; diadenosine polyphosphate; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATP; adenosine 5′-triphosphate; BN-PAGE; blue native-p

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling

Keywords: GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinases; SA-β-Gal; senescence-associated-β-galactosidase; FACS; fluorescence-activated cell sorting; CCK-8; cell counting kit-8; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Spatial encryption of G protein-coupled receptor signaling in endosomes; Mechanisms and applications

Keywords: AKT (PKB); protein kinase B; AP2; adaptor protein 2; APPL1; adaptor protein containing PH domain, PTB domain, and Leucine zipper motif; ARRDC; arresting domain containing; Β1AR; B2AR, beta-adrenergic receptor 1 or 2; CCP; clathrin coated pit; CXCR4; chem

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

MC1R signaling. Intracellular partners and pathophysiological implications

Keywords: AC; adenylyl cyclase; ACTH; adrenocorticotropic hormone; ARRB; β-arrestin; ASIP; agouti signal protein; CBD103; dog β-defensin-3; CREB; cAMP responsive-element binding protein; EDN1; endothelin 1; ER; endoplasmic reticulum; ERK; extracellular signal-reg

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2017 سفارش ترجمه

Roles of Mas-related G protein-coupled receptor X2 on mast cell-mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases

Keywords: G protein-coupled receptor; MRGPRX2; mast cells; host defense peptides; neuropeptides; drug-induced pseudoallergy; chronic urticaria; asthma; C3aR; Anaphylatoxin C3a receptor; CGRP; Calcitonin gene-related peptide; CTMC; Connective tissue mast cell; C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17

Keywords: Purinergic receptors; Oligodendrocytes; Remyelination; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATX; autotaxin; CNS; central nervous system; DRG; dorsal root ganglion; EAE; experimental autoimmune encephalomyelitis; GDNF; glial cell de

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Feedback regulation of G protein-coupled receptor signaling by GRKs and arrestins

Keywords: GPCR; G protein; Arrestin; GRK; Signal transduction; Biased signaling;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins

Keywords: GPCR; β-arrestin; KLHL12; ubiquitination; dopamine D4 receptor; β2AR; β2-adrenergic receptor; ADHD; attention deficit hyperactivity disorder; BTB; bric à brac 1, tramtrack, and broad-complex; co-IP; co-immunoprecipitation; CXCR4; C-X-C chemokine recep

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor

Keywords: AC; adenylyl cyclase; α-neo; α-neoendorphin; β-arr1 and β-arr2; β-arrestin 1 and 2; BRET; bioluminescence resonance energy transfer; CHO; Chinese hamster ovary; DAMGO; d-Ala2-N-MePhe4-Gly-ol enkephalin; endo; endomorphin; pERK; extracellular signal r

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Research ReportInvolvement of NFκB signaling in mediating the effects of GRK5 on neural stem cells

Keywords: AD; Alzheimer׳s disease; GPCR; G protein-coupled receptor; GRK; G-protein receptor kinase; IL-6; interleukin-6; IL-1β; interleukin-1β; NAC; N-acetyl cysteine; NFκB; nuclear factor κB; NPCs; neural progenitor cells; NSCs; neuron stem cells; PKA; prote

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The carboxy-terminal tail or the intracellular loop 3 is required for β-arrestin-dependent internalization of a mammalian type II GnRH receptor

Keywords: GnRH receptor; Internalization; G protein-coupled receptor kinase; β-Arrestin; ERK; DMEM; Dulbecco's modified Eagle medium; EC50; concentration that stimulates half-maximal IP production; ERK; extracellular signal-regulated kinases; FSH; follicle-stimula

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The dichotomy of the Insulin-like growth factor 1 receptor: RTK and GPCR: friend or foe for cancer treatment?

Keywords: IGF-1R; RTK; GPCR; beta-Arrestin; GRK; Biased signalling; Cancer; Ubiquitination;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Cannabinoid receptor interacting protein (CRIP1a) attenuates CB1R signaling in neuronal cells

Keywords: 2-AG; 2-arachidonoylglycerol; BSA; bovine serum albumin; CB1; cannabinoid receptor; CP55940; (−)-cis-3-[2-Hydroxy-4-(1,1-dimethyl­heptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol; CRIP1a; Cannabinoid Receptor Interacting Protein 1a; DAGL; diacylgly

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

PDZK1/NHERF3 Differentially Regulates Corticotropin-releasing Factor Receptor 1 and Serotonin 2A Receptor Signaling and Endocytosis

Keywords: ANOVA; analysis of variance; β 1AR; β 1-adrenergic receptor; β2AR; β2-adrenergic receptor; CRF; corticotropin-releasing factor; CRFR1; CRF receptor 1; CRFR2; CRF receptor 2; ERK1/2; extracellular signal-regulated kinase; GKAP; guanylate kinase-associa

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

γ-Glutamyl cysteine and γ-glutamyl valine inhibit TNF-α signaling in intestinal epithelial cells and reduce inflammation in a mouse model of colitis via allosteric activation of the calcium-sensing receptor

Keywords: CaSR; calcium-sensing receptor; GPCR; G-protein-coupled receptor; IBD; inflammatory bowel disease; CD; Crohn's disease; UC; ulcerative colitis; γ-EC; γ-glutamyl cysteine; γ-EV; γ-glutamyl valine; GRK; GPCR kinase; TRAF; TNF-receptor-associated factor;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

The CXC chemokine receptors of fish: Insights into CXCR evolution in the vertebrates

Keywords: ACKR; atypical chemokine receptor; AGTR; angiotensin II receptor; AP-2; activated protein 2; CCR; CC chemokine receptors; CD; cluster of differentiation; CXC; CXC chemokine; CXCR; CXC chemokine receptor; CX3CR; CX3C receptor; ERK; extracellular regulated

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

New paradigms in GPCR drug discovery

Keywords: cAMP; 3′,5′-cyclic adenosine monophosphate; ADP; adenosine 5′- diphosphate; GPCR; G protein-coupled receptor; TM; transmembrane helix; ERK; extracellular signal-regulated kinase; T4L; T-4 lysozyme; BRIL; thermostabilized apocytochrome b562; StaRs; s

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Cardioprotective potential of annexin-A1 mimetics in myocardial infarction

Keywords: Ac2-26; Cardioprotection; Cardiomyopathy; Formyl peptide receptors; Inflammation; Ischemia-reperfusion; Aβ42; 42-amino acid beta-amyloid peptide; ABC; ATP-binding cassette; Ac2-26; N-terminal-derived annexin-A1 peptide (acetyl-AMVSEFLKQAWIENEEQEYVVQTVK

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms that underlie the internalization and extracellular signal regulated kinase 1/2 activation by PKR2 receptor

Keywords: AT1AR; angiotensin type 1A receptor; ConA; Concanavalin A; DN-GRK; dominant-negative G-protein-coupled receptor kinase 2; EGFP; enhanced green fluorescent protein; ERK; extracellular signal regulated kinase; GPCR; G-protein-coupled receptors; GRK; GPCR ki

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Phosphodiesterase 4 interacts with the 5-HT4(b) receptor to regulate cAMP signaling

Keywords: 5-HT; 5-hydroxytryptamine; AKAP; A-kinase anchoring protein; DMSO; dimethyl sulfoxide; GRK; G protein-coupled receptor kinase; HEK293; human embryonic kidney cell line; IBMX; isobutylmethylxanthine; IP; immunoprecipitation; PDE; phosphodiesterase; PKA; pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins

Keywords: mGlu7 receptors; GRK; Arrestins; MAP kinases; Jun kinases; Signaling regulation; GPCR; G protein-coupled receptor; mGlu; metabotropic glutamate receptor; GRK; G protein-coupled receptor kinase; FSK; forskolin; L-AP4; l-2-amino-4-phosphonobutanoate; MAPK;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain

Keywords: ANOVA; analysis of variance; Ce; cerebellum; CEB; cell extraction buffer; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; Co; cerebral cortex; CSNK2a2; alpha prime subunit of casein kinase II; EDTA; ethylenediaminetetraacetic acid; EGTA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Homologous desensitization of human histamine H3 receptors expressed in CHO-K1 cells

Keywords: Histamine; H3 receptor; Desensitization; GRK; CHO-K1 cells; Neuromodulation; H3R; histamine H3 receptor; GPCR; G protein-coupled receptor; GRK; GPCR kinase; RAMH; R-α-methylhistamine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of Bombyx neuropeptide G protein-coupled receptor A4 via a Gαi-dependent signaling pathway by direct interaction with neuropeptide F from silkworm, Bombyx mori

Keywords: Neuropeptide; GPCR; Signaling; Arrestin; MAP kinases; AKH; adipokinetic hormone; cAMP; cyclic AMP; CRE; cAMP-response element; EGFP; enhanced green fluorescent protein; ERK1/2; extracellular signal-regulated kinase1/2; Gi; inhibitory GTP-binding protein o

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling

Keywords: BSA; bovine serum albumin; CHO; Chinese hamster ovary; CRC; concentration-response curve; EC50; half maximimal excitatory concentration; Emax; maximal efficacy versus a defined control; FBS; fetal bovine serum; GPCR; G protein coupled receptor; GRK; GPC

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه