دانلود مقالات ISI درباره Hek293 + ترجمه فارسی

هوموستازیس مس میتوکندری و زوال آن در بیماری ویلسون

Mitochondrial copper homeostasis and its derailment in Wilson disease

Keywords: ATP7B; ATPase copper transporting beta; CcO; cytochrome c oxidase; CCS; copper chaperone for superoxide dismutase; COX1; cytochrome c oxidase subunit 1; COX2; cytochrome c oxidase subunit 2; COX11; cytochrome c oxidase assembly protein 11; COX17; cytochro

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

دارچین، چشم انداز امیدوار کننده به بیماری آلزایمر

Cinnamon, a promising prospect towards Alzheimer's disease

Keywords: AD; Alzheimer's disease; PPs; polyphenols; EGCG; epigallocatechin gallate; NFTs; neurofibrillary tangles; ACh; acetylcholine; Aβ; amyloid-beta; APP; amyloid precursor protein; PS-1; presenilin-1; PS-2; presenilin-2; AChE; acetylcholine esterase; Cdk5;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

ویژگی ها و نتایج داروها برای درمان ترکیبی به عنوان استراتژی چند هدفه ای برای مبارزه با بیماری آلزایمر

Features and outcomes of drugs for combination therapy as multi-targets strategy to combat Alzheimer's disease

Keywords: AD; Alzheimer's disease; Aβ; β-amyloid peptide; NFTs; neurofibrillary tangles; EOAD; early-onset AD; LOAD; late-onset AD; OMOT; One-molecule-one-target; ROS; reactive oxygen species; CDMT; Combination-drugs-multi-targets; BBB; blood brain barrier; DDT;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

داروهای دقیق برای بیماری آلزایمر

Precision pharmacology for Alzheimer's disease

Keywords: Aβ1-42; 42-amino acid-long Aβ peptide; AD; Alzheimer's disease; ADAPT; Alzheimer's Disease Anti-Inflammatory Prevention Trial; ADAS-Cog; Alzheimer's Disease Assessment Scale-Cognitive Subscale; ADCS-ADL; Alzheimer's Disease Cooperative Study Activ

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

تعادل و شرایط: سیستم آنژیوتانسین رنین در بهبود زخم و فیبروز

Balance and circumstance: The renin angiotensin system in wound healing and fibrosis

Keywords: Skin; TGFβ; Inflammation; Extracellular matrix; Therapy; ACE; angiotensin-converting enzyme; ACE2; angiotensin-converting enzyme 2; AT1; angiotensin II receptor type 1; ADAM; a disintegrin and metalloproteinase family sheddase; AT2; angiotensin II recept

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

نقش پروتئین پریون سلولی در انتقال آمیلوئید بین-نیوورون

Role of cellular prion protein in interneuronal amyloid transmission

Keywords: AA; amino acid; Aβo; oligomeric β-amyloid; Aβ; β-amyloid; AD; Alzheimer's disease; α7nAChR; α7 nicotinic acetylcholine receptor; ALS; amyotrophic lateral sclerosis; APLP1; amyloid beta precursor-like protein 1; APP; amyloid precursor protein; β-A

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

پانسمان زنجیری از پلیمرهای طبیعی: بررسی در مورد کامپوزیت های مبتنی بر هوموپلی ساکارید

Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites

Keywords: AgNO3; silver nitrate; AgSD; silver sulfadiazine; ATP; adenosine triphosphate; B. subtilis; Bacillus subtilis; C. albicans; Candida albicans; C. freundii; Citrobacter freundii; CFC; colony forming count; CuO; copper oxide; DAPI; 4',6-diamidino-2-phenylind

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2018 سفارش ترجمه

تعامل بین رین آسیل گلوکوروناید و متوترکسات بر اساس آنیون های حمل کننده آلی انسان

Interaction between rhein acyl glucuronide and methotrexate based on human organic anion transporters

Keywords: Rhein; Rhein acyl glucuronide; Methotrexate; Organic anion transporter; Drug-drug interaction; AUC; area under the plasma time-concentration curve; ES; estrone sulfate; HBSS; Hank's balanced salt solution; HEK293; human embryonic kidney 293; IS; internal

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

استئوپتروز، با تاکید بر رویکردهای بالقوه برای درمان

Osteopetroses, emphasizing potential approaches to treatment

Keywords: ADO; Autosomal dominant osteopetroses; ATP6V1B1; V-type proton ATPase subunit B, kidney isoform; CAII; carbonic anhydrase type II; Cas9; CRISPR associated protein 9; CLCN7; Chloride channel 7; CRISPR; clustered regularly interspaced short palindromic repe

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

غلظت پروتئین وابسته به نوع 2 متابولیسم ترومبوکلئوتامیناز به اگزوزوم ها در شرایط سلولی تنش زا

Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions

Keywords: ALIX; apoptosis-linked gene-2-interacting protein X; BAG3; BCL2-associated athanogene 3; BAP; 5-(biotinamido)pentylamine; ESCRT; endosomal sorting complex required for transport; HEK293; human embryonic kidney cells; MEF; murine embryonic fibroblasts; mHt

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

طراحی، سنتز و ارزیابی آنالوگهای اندومورفین جدید با افزایش ضد انعقادی مرکزی پس از تجویز محیطی

Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration

Keywords: BBB; blood-brain barrier; Boc; tert-butyloxycarbonyl; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; DAMGO; H-Tyr-d-Ala-Gly-NMePhe-Gly-ol; DCM; dichloromethane; DIEA; N,N-diisopropylethylamine; DOR; δ-opioid receptor; DPDPE; Tyr-c(d

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

آزمایش غربالگری مبتنی بر سلول برای فعالیت ضد التهابی ترکیبات زیست فعال

Cell-based screening assay for anti-inflammatory activity of bioactive compounds

Keywords: Reporter assay; NF-κB; Anti-inflammatory; HEK293; Sulphoraphane; Lutein; SCFA; Butyrate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

مکانیزم های رمز گشایی که از طریق آن کدون سکوت تغییر می کند، بر عملکرد و بیوگرافی پروتئین تاثیر می گذارد

Decoding mechanisms by which silent codon changes influence protein biogenesis and function

Keywords: A; adenine; ACMG; American College of Medical Genetics; Ala; alanine; Asp; aspartic acid; BCL2L12; B-cell lymphoma-2-like protein 12; BRCA1; breast cancer-1 gene; C; cytosine; CCDS; Consensus Coding Sequence; CD; circular dichroism; CDC; coding sequence;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

یک سیستم بیان ساده، قوی و بسیار کارآمد برای تولید آنتیبادی ها

A simple, robust and highly efficient transient expression system for producing antibodies

Keywords: HEK-293F; FreeStyle™ 293-F; HEK-293; human embryonic kidney 293 cell line; CMV; cytomegalo virus; SVLT; the large T antigen of the SV40 virus; DoE; design of experiments; Medium; FreeStyle™ 293 expression medium; Optimem; opti-MEM® I reduced-serum me

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

ژنتیک تریم ضروری: از فنوتیپ به ژن، بینش از هر دو مطالعات انسان و موش

Genetics of essential tremor: From phenotype to genes, insights from both human and mouse studies

Keywords: Essential tremor; Brain; Genetics; Human population; Mouse models; Pathophysiology; ABA; Allen brain atlas; AβPPswe/PS1ΔE9; amyloid-β protein precursor and presenilin-1; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATP; adenosine tri-ph

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

توکسین اورامیک از طریق تداخل با گلوکورونید شدن و تنفس میتوکندری، توانایی متابولیک کلیه را مهار می کند

Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration

Keywords: 7-OHC; 7-hydroxycoumarin; 7-OHCG; 7-hydroxycoumarin glucuronide; AA; antimycin A; ciPTEC; conditionally immortalized human renal proximal tubule epithelial cells; CKD; chronic kidney disease; CMPF; 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid; CRF; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

سیگنال های شیمیایی و گیرنده های آنها در سیستم عصبی بویایی

Chemosensory signals and their receptors in the olfactory neural system

Keywords: ACTH; adrenocorticotropic hormone; BT; 2-sec-butyl dihydrothiazole; CAII; carbonic anhydrase II; CO2; carbon dioxide; CS2; carbon disulfide; cVA; 11-cis-vaccenyl acetate; DB; dehydro-exo-brevicomin; GC-D; guanylyl cyclase D; ELG; extraorbital lacrimal gla

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Optimising the transient expression of GABA(A) receptors in adherent HEK293 cells

Keywords: GABAA receptor; Ligand-gated ion channel; Transient expression; HEK293; IMP; integral membrane protein; BacMam; baculovirus infection of mammalian cells; CaP; calcium phosphate; PEI; polyethyleneimine; SV40; Simian vacuolating virus 40; SV40-ori; SV40 ori

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2019 سفارش ترجمه

Analysis of the pharmacological properties of JWH-122 isomers and THJ-2201, RCS-4 and AB-CHMINACA in HEK293T cells and hippocampal neurons

Keywords: Win 55,212-2 (PubChem CID: 6604176); CP-55,940 (PubChem CID: 4412255); Δ9-THC (PubChem CID: 16078); rimonabant (PubChem CID: 104850); JWH-122-4 (PubChem CID: 44466638); RCS-4 (PubChem CID: 56841530); THJ-2201 (PubChem CID: 91864533); AB-CHMINACA (PubChem

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro approach to elucidate the relevance of carboxylesterase 2 and N-acetyltransferase 2 to flupirtine-induced liver injury

Keywords: AADAC; arylacetamide deacetylase; AcetylCoA; acetyl coenzyme A; Ad; adenovirus; BNPP; bis-(p-nitrophenyl) phosphate; BSO; l-buthionine sulfoximine; CES; carboxylesterase; DFP; diisopropyl phosphorofluoride; DMSO; dimethyl sulfoxide; Eserine; sulfate physo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Ubiquitination and SUMOylation in the chronic inflammatory tumor microenvironment

Keywords: Inflammation-associated cancer; Ubiquitin-proteasome system (UPS); Small ubiquitin-like modifier (SUMO); Tumor microenvironment; Cytokine profile; Transcription factors; 15d-PGJ2; 15-Deoxy-Delta-12,14-prostaglandin J2; AR; androgen receptor; Ala; alanine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Induction of oxidative stress by long-term treatment of live HEK293 cells with therapeutic concentration of lithium is associated with down-regulation of δ-opioid receptor amount and function

Keywords: AAS; atomic absorption spectroscopy; Ab; antibody; BD; bipolar disorder; DADLE; (2-d-alanine-5-d-leucine)-enkephalin = Tyr-d-Ala-Gly-Phe-d-Leu; DCF; 2′,7′-dichlorofluorescein; DCFH-DA; 2′,7′-dichlorofluorescin diacetate (synonym dichlorodihydr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

MEF2A regulates Calpain 3 expression in L6 myoblasts

Keywords: MEF2; myogenic enhancer factor 2; Calpain; calcium-dependent, non-lysosomal cysteine protease; CAPN3; Calpain 3, calcium-dependent, non-lysosomal cysteine protease3; FoxO; Forkhead box O; HEK293; human embryonic kidney cells 293; EMSA; electrophoretic mob

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

7-Methoxyderivative of tacrine is a 'foot-in-the-door' open-channel blocker of GluN1/GluN2 and GluN1/GluN3 NMDA receptors with neuroprotective activity in vivo

Keywords: Behavioural experiment; Electrophysiology; Glutamate receptor; Human pathogenic mutation; Ion channel; Pharmacology; AD; Alzheimer's disease; AMPA; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid; ANOVA; Analysis of Variance; CAS; Czech Academy o

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

HDAC11 is a regulator of diverse immune functions

Keywords: APC; antigen presenting cell; CTCL; cutaneous T-cell lymphoma; DAMP; Damage associated molecular pattern; DC; dendritic cell; FDA; U.S. Food and Drug Administration; GVHD; graft versus host disease; HAT; histone acetyltransferase; HDAC; histone deacetylas

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

The association of spinophilin with disks large-associated protein 3 (SAPAP3) is regulated by metabotropic glutamate receptor (mGluR) 5

Keywords: SAPAP3; SAP90/PSD-95 associated protein 3; mGluR; Metabotropic glutamate receptor; PKC; Protein kinase C; PP1; Protein phosphatase 1; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; OCD; Obsessive Compulsive Disorder; PD; Parkinson

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Immunomodulatory, hemolytic and cytotoxic activity potentials of triterpenoid saponins from eight Cephalaria species

Keywords: Cytotoxic activity; Hemolytic activity; Immunomodulatory activity; Cephalaria; Caprifoliaceae; Triterpene saponin; HeLa; Human Cervix Adenocarcinoma; A549; Human Lung Adenocarcinoma; HEK293; Human Embryonic Kidney Cells; MTT; 3-(4,5-Dimethylthiazol-2-yl)-

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Aristolochic acid I interferes with the expression of BLCAP tumor suppressor gene in human cells

Keywords: Aristolochic acid; Bladder cancer associated protein; BLCAP; HEK293; Carcinogenesis;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy

Keywords: d-amino acid oxidase (DAAO); Propiverine; Peroxisomal import; Protein trafficking; Cytosolic and nuclear protein mislocalization and accumulation; Co-immunoprecipitation (Co-IP); Nano-LC-ESI-MS/MS; Immunohistochemistry (IHC); hDAAO, rDAAO; human and rat d

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Structural and functional analysis of two novel somatostatin receptors identified from topmouth culter (Erythroculter ilishaeformis)

Keywords: HEK293; Human Embryonic Kidney 293; SSTRs; somatostatin receptors; mRNAs; messenger-ribonucleic acid; SS; Somatostatin; MC-LR; microcystin-LR; E2; 17β-estradiol; MCs; microcystins; DMSO; dimethyl sulfoxide; MS-222; methanesulfonate-222; cDNA; complementa

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

The ciliary protein Rpgrip1l in development and disease

Keywords: BB; Basal body; Bbs; Bardet-Biedl syndrome; C. elegans; Caenorhabditis elegans; CC; Coiled-Coil; Cep290; Centrosomal Protein 290; COACH; Cerebellar Vermis Aplasia Oligophrenia Congenital Ataxia Coloboma Hepatic Fibrosis; CRD; Cone Rod Dystrophy; Cux1; Cut

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases

Keywords: AUClast; Area under concentration-time curve; CL; Total clearance; COLO205; Intestinal epithelial cells; Cmax; Maximal serum concentration; DC; Dendritic Cells; DMEM; Dulbecco's modified Eagle's medium; DSS; Dextran sulfate sodium salt; EC50; Half max

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of neuromedin U (NMU), neuromedin S (NMS) and their receptors (NMUR1, NMUR2) in chickens

Keywords: c; chicken; h; human; NMU; neuromedin U; NMS; neuromedin S; NMUR1; NMU receptor 1; NMUR2; NMU receptor 2; NURP; NMU precursor-related peptide; NSRP; NMS precursor-related peptide; HEK293; human embryonic kidney 293 cells; ERK; extracellular signaling-regu

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques

Keywords: 17,18-Epoxyeicosatetraenoic acid; G protein-coupled receptor 40; ω3 fatty acid; contact hypersensitivity; dermatitis; neutrophil; ALA; α-Linolenic acid; APC; Allophycocyanin; Chi3l3; Chitinase 3-like 3; CYP; Cytochrome P450; DAPI; 4′-6-Diamidino-2

دانلود رایگان متن کامل مقاله ISI 84 صفحه سال انتشار : 2018 سفارش ترجمه

Indoleamine 2,3-dioxygenase regulates T cell activity through Vav1/Rac pathway

Keywords: HEK293; Human Embryonic Kidney 293 cells; FBS; Fetal bovine serum; IDO; Indoleamine 2,3-dioxygenase; IL; interleukin; PBMCs; Peripheral blood monouclear cells; TIL-Ts; T cells of tumor infiltrating lymphocytes; TCR; T cell receptor; Indoleamine 2,3-dioxyg

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)

Keywords: Transport protein; ATP binding cassette transporter; Transport inhibition; DDI, drug-drug-interaction; Membrane vesicles; HEK293;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

High-level expression and purification of soluble form of human natural killer cell receptor NKR-P1 in HEK293S GnTI− cells

Keywords: NKR-P1; CD161; klrb1; NK cells; HEK293; LLT1; CTL; C-type lectin-like; GnTI−; N-acetylglucosaminyltransferase I negative; HEK; human embryonic kidney; LLT1; lectin-like transcript 1; lPEI; linear polyethylenimine; MALS; multi-angle light scattering; NK;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells

Keywords: MLK3; Mixed Lineage Kinase 3; MLK4; Mixed Lineage Kinase 4; MAPK; mitogen-activated protein kinase; MAP3K; MAPK kinase kinase; MAP2K; MAPK kinase; JNK; c-Jun N-terminal kinase; siRNA; short interfering RNA; ERK; extracellular signal-regulated kinase; HEK2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A high density CHO-S transient transfection system: Comparison of ExpiCHO and Expi293

Keywords: CHO cells; HEK293 cells; Transient transfection; Post-translational modification; Glycosylation; BLI; Biolayer Interferometry; CHO; Chinese Hamster Ovary; CV; Column Volume; EBNA; Epstein-Barr Nuclear Antigen-1; HEK293; Human Embryonic Kidney; PTM; Post-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The dual modulatory effects of efavirenz on GABAA receptors are mediated via two distinct sites

Keywords: Recombinant GABAA receptors; Adverse CNS side effects; Picrotoxin; AIDS; Antiretroviral; BDZ; benzodiazepine; CNS; central nervous system; DMSO; dimethyl sulfoxide; DZ; diazepam; EFAV; efavirenz; FLU; flumazenil; LGICs; ligand-gated ion channels; HEK293;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Novel signaling of dynorphin at κ-opioid receptor/bradykinin B2 receptor heterodimers

Keywords: AC; adenylyl cyclase; B1R; bradykinin B1 receptor; B2R; bradykinin B2 receptor; BK; bradykinin; BRET; bioluminescence resonance energy transfer; CFP; cyan fluorescent protein; CNS; central nervous system; CRE; cAMP-response element; CREB; cAMP-response el

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Mutations in two large pedigrees highlight the role of ZNF711 in X-linked intellectual disability

Keywords: ADID; autosomal dominant intellectual disability; ARID; autosomal recessive intellectual disability; CADD; Combined Annotation Dependent Depletion; cDNA; complementary deoxyribonucleic acid; DNA; deoxyribonucleic acid; ExAC; Exome Aggregation Consortium;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Protein toxins of the Echis coloratus viper venom directly activate TRPV1

Keywords: 2-APB; 2-aminoethoxydiphenyl borate; Cap; capsaicin; DkTx; double-knot toxin; HPLC; high performance liquid chromatography; HEK293; human embryonic kidney cells 293; NGF; nerve growth factor; TRPV1; Transient Receptor Potential Vanilloid 1; TG; trigeminal

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of therapeutic concentration of lithium on live HEK293 cells; increase of Na+/K+-ATPase, change of overall protein composition and alteration of surface layer of plasma membrane

Keywords: ABC; ammonium bicarbonate; ACN; acetonitrile; BD; bipolar disorder; CBB; colloidal Coomassie Brilliant Blue G-250; CK; creatine kinase; DMPC; dimirystoylphosphatidylcholine; DPPS; dipalmitoylphosphatidylserine; DMPS; dimirystoylphosphatidylserine; DLPS; d

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Current In Vitro Methods to Determine Hepatic Kpuu: A Comparison of Their Usefulness and Limitations

Keywords: active transport; passive diffusion/transport; hepatic metabolism; biliary excretion; distribution; disposition; tissue partition; protein binding; hepatocytes; human liver microsomes; ABT; 1-aminobenzotriazole; AFE; average fold error; CLint; intrinsic c

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

High glucose down-regulates microRNA-181a-5p to increase pro-fibrotic gene expression by targeting early growth response factor 1 in HK-2 cells

Keywords: COL I; collagen I; DKD; diabetic kidney disease; DMEM; Dulbecco's modified Eagle's medium; DN; diabetic nephropathy; ECM; extracellular matrix; Egr1; early growth response factor 1; ESRD; end-stage renal disease; FBS; fetal bovine serum; FN; fibronectin;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress

Keywords: BSA; Bovine Serum Albumin; BTB; Broad complex, Tramtrack, and Bric-a-Brac; cDNA; Complementary DNA; CFP; Cyan Fluorescent Protein; CVD; cardiovascular disease; DCF(H); 2',7'-dichlorofluorescin; DMOG; Dimethyloxalylglycine, N-(Methoxyoxoacetyl)-glycine met

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma

Keywords: Regulated Cell Death; Antitumor Immunity; HMGB1; ATP; AURKA; aurora kinase A; DAMPs; damage-associated molecular patterns; GSK3β; glycogen synthase kinase 3 beta; HEK293; human embryonic kidney 293; HPDE; human pancreatic duct epithelial cell; ICD; immun

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Src-family tyrosine kinases and the Ca2 + signal

Keywords: 5-HT6; serotonin receptor 6; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid; ADPR; ADP-ribose; AMPA; α-amino-3-hydr

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

Keywords: CRISPR; Clustered regulatory interspaced short palindromic repeats; Cas9; CRISPR-associated protein 9; HEK293; human embryonic kidney 293 cells; HRP; horseradish peroxidase; Nox4-HEK293; HEK293 cells stably expressing Nox4; PMA; phorbol 12-myristate 13-ac

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه