دانلود مقالات ISI درباره Ic50 + ترجمه فارسی

Optimization of ultrasound-assisted extraction of antioxidant compounds from Tunisian Zizyphus lotus fruits using response surface methodology

Keywords: Optimization; Response surface methodology; Central composite rotatable design; Ultrasound-assisted system; Total phenolic content; Phosphomolybdenum assay; 2,2-Diphenyl-1-picrylhydrazyl radical scavenging activity; DPPH; 2,2-diphenyl-1-picrylhydrazyl; TA

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2015 سفارش ترجمه

The membrane-active amphibian peptide caerin 1.8 inhibits fibril formation of amyloid β1-42

Keywords: Aβ42; Amyloid β1-42 peptide; AD; Alzheimer's disease; APP; Amyloid precursor protein; HPLC; High performance liquid chromatography; IC50; Half maximal inhibitory concentration; MALDI; Mass analysed laser desorption ionization; MD; Molecular dynamics;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis: In silico screening and in vitro validation

Keywords: mtDAH7Ps; Mycobacterium tuberculosis; E-pharmacophore model; IC50; Molecular dynamics;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2015 سفارش ترجمه

Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease

Keywords: CVB3; Cosxackievirus B3; CVB3 3Cpro; Cosxackievirus B3 3C protease; FRET; fluorescence resonance energy transfer; l-DOPA; levodopa; Boc; tert-butyloxycarbonyl; TFA; trifluoroacetic acid; DCM; dichloromethane; IC50; the half maximal inhibitory concentratio

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours

Keywords: 1H NMR; Proton nuclear magnetic resonance; AO; Acridine orange; CMC; Critical micellar concentration; cRGDfK; Cyclo(-Arg-Gly-Asp-D-Phe-Lys); DMEM; Dulbecco's modified eagle medium; DMSO; Dimethyl sulfoxide; DNM; Docetaxel loaded TPSA nanomicelles; DPBS;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2015 سفارش ترجمه

Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR

Keywords: acetyl-CoA; acetyl coenzyme A; ALARM NMR; a La assay to detect reactive molecules by nuclear magnetic resonance; Asf1; anti-silencing function 1; AZ; AstraZeneca; BME; β-mercaptoethanol; BSA; bovine serum albumin; CoA; coenzyme A; CPM; N-[4-(7-diethylami

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2015 سفارش ترجمه

Arginine-containing peptides as potent inhibitors of VIM-2 metallo-β-lactamase

Keywords: DLS; dynamic light scattering; IC50; half-inhibitory concentration; MBL; metallo-β-lactamase; pNA; para-nitroanilide; Antibiotic resistance; Metallo-β-lactamases; Peptide inhibitors; Protein aggregation;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of the potent and selective DP1 receptor antagonist, asapiprant (S-555739), in animal models of allergic rhinitis and allergic asthma

Keywords: AHR; airway hyper-responsiveness; AUC; area under the curve; BALF; bronchoalveolar lavage fluid; cAMP; cyclic adenosine monophosphate; CRTH2; chemoattractant receptor homologous molecule expressed on Th2 cells; Cmax; maximum concentration achieved after d

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2015 سفارش ترجمه

3-Nitrotriazole-based piperazides as potent antitrypanosomal agents

Keywords: Nitrotriazoles; Piperazides; Trypanocidal; Leishmanicidal; Chagas disease; NTD; neglected tropical diseases; T. brucei; Trypanosoma brucei; HAT; human African trypanosomiasis; T. cruzi; Trypanosoma cruzi; Bnz; benznidazole (N-benzyl-2-(2-nitro-1H-imidaz

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2015 سفارش ترجمه

Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

Keywords: Coumarins; Anticancer; Synthesis; Targets; SAR; IC50; ARI; aromatase inhibitor; CAM; choriallanotoic membrane; CDC; cell cycle division protein; CDK2; cyclin dependent kinase 2; CDKN1A; cyclin-dependent kinase inhibitor 1A; CYP; cytochromes P450; DDIT4; D

دانلود رایگان متن کامل مقاله ISI 72 صفحه سال انتشار : 2015 سفارش ترجمه

N-heterocyclic carbenes (NHC) with 1,2,4-oxadiazole-substituents related to natural products: Synthesis, structure and potential antitumor activity of some corresponding gold(I) and silver(I) complexes

Keywords: 1,2,4-Oxadiazoles; Gold-NHC; Silver-NHC; Natural product analogs; Anti-tumor activity; Bioisosters; NHC; N-heterocyclic carbene; DCM; dichloromethane; IC50; half maximal inhibitory concentration; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

دانلود رایگان متن کامل مقاله ISI 84 صفحه سال انتشار : 2015 سفارش ترجمه

N-(1′-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia

Keywords: Acylhydrazones; Colchicine; Tubulin; Microtubule assembly; Cell migration; Leukemia; Cancer; ABT-751; N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide; CHNS; elemental analysis; DAMA-colchicine; N-deacetyl-N-(2-mercaptoacetyl)-colchici

دانلود رایگان متن کامل مقاله ISI 88 صفحه سال انتشار : 2015 سفارش ترجمه

Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1

Keywords: Imidazo[1,2-b]pyridazine; Anti-apicomplexan; Toxoplasma gondii; Toxoplasma gondii calcium-dependent protein kinase 1; IC50; 50% inhibitory concentration; EC50; 50% effective concentration; CC50; 50% cytotoxic concentration; SAR; structure-activity relatio

دانلود رایگان متن کامل مقاله ISI 129 صفحه سال انتشار : 2015 سفارش ترجمه

The genus Sida L. - A traditional medicine: Its ethnopharmacological, phytochemical and pharmacological data for commercial exploitation in herbal drugs industry

Keywords: ABTS; 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid; AGS; human gastric adenocarcinoma; AIU; aspirin induced ulcer; ALP; alkaline phosphatase; ALT; serum alanine aminotransferase; AP; aerial part; APPLIU; aspirin plus pylorus ligation induced ulc

دانلود رایگان متن کامل مقاله ISI 164 صفحه سال انتشار : 2015 سفارش ترجمه

Brief communicationHepaRG cell line as an in vitro model for screening drug-drug interactions mediated by metabolic induction: Amiodarone used as a model substance

Keywords: AM; amiodarone; CYP450; cytochrome P450; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; HPLC-DAD; high-performance liquid chromatography-diode array detection; IC50; half-maximal inhibitory concentration; IS; internal standard; MDEA; mono-N-desethylam

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Cycloastragenol, a triterpene aglycone derived from Radix astragali, suppresses the accumulation of cytoplasmic lipid droplet in 3T3-L1 adipocytes

Keywords: RA; Radix astragali; CAG; cycloastragenol; AG-IV; astragaloside IV; ERK; extracellular signal-regulated protein kinase; PFA; paraformaldehyde; Lova; Lovastatin; GSH; reduced glutathione level; ROS; reactive oxygen species; MMP; mitochondrial membrane pote

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Direct and selective small-molecule inhibition of photosynthetic PEP carboxylase: New approach to combat C4 weeds in arable crops

Keywords: C4 photosynthesis; PEP carboxylase; C4 specific inhibitor; Weed; Selective herbicide; aa; amino acid; AG 1433; 2-(3,4-dihydroxyphenyl)-6,7-dimethylquinoxaline; DCDP; 3,3-Dichloro-2-(dihydroxyphosphinoyl-methyl)-propenoate; DMF; N,N-Dimethylformamide; DMSO

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Variability and the genotypic effect on antioxidant activity, total phenolics, carotenoids and ascorbic acid content in seventeen natural population of Seabuckthorn (Hippophae rhamnoides L.) from trans-Himalaya

Keywords: Functional food; Nutrition; PCA; Seabuckthorn; Vitamin; DPPH; 2,2-diphenyl-1-picrylhydrazyl; FW; fresh weight; IC50; inhibitory concentration; L*; colour in lightness; PCA; principal component analysis; PR; phosphotungstate reagent; SBT; Seabuckthorn; TAC

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The antioxidant properties of new dimer and two monomers of phenolic acid amides isolated from Limoniastrum guyonianum

Keywords: DPPH; 2,2-Diphenyl-1-picrylhydrazyl; IC50; inhibition concentration at 50 percent; EC50; effective concentration at which the absorbance was 0.5; BHT; butylated hydroxytoluene; BHA; butylated hydroxyanisole; n-hept; n-heptane; EtOAc; ethyl acetate; MeOH;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYP1A2) activity

Keywords: Herbal active constituents; CYP1A2; Fluorescence-based enzyme assay; Inhibitory effect; CEC; 3-cyano-7-ethoxycoumarin; CYP; cytochrome P450; DMSO; dimethylsulfoxide; Km; Michaelis-Menten constant; Vmax; maximum velocity; IC50; the half maximal (50%) inh

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The relationship between in vivo antiviral activity and pharmacokinetic parameters of peramivir in influenza virus infection model in mice

Keywords: PK; pharmacokinetic; IV; intravenous; PD; pharmacodynamic; AUC; area under the concentration-time curve; Cmax; maximum concentration; IC50; 50% inhibitory concentration; IC95; 95% inhibitory concentration; T>IC95; time that drug concentration exceeds IC

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Anti-influenza virus activity of the ethanolic extract from Peperomia sui

Keywords: CC50; 50% cytotoxic concentration; CPE; cytopathic effect; DAPI; (4′,6-diamidino-2-phenylindole); DMEM; Dulbecco׳s modified Eagle׳s medium; EC50; half maximal effective concentration; FITC; fluorescein isothiocyanate; HA; hemagglutinin; IC50; half-max

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Antimicrobial, antioxidant and cytotoxic activities of propolis from Melipona orbignyi (Hymenoptera, Apidae)

Keywords: AAPH; 2,2′-Azobis-(2-amidinopropane) dihydrochloride; A. Mellifera; Apis mellifera; BSTFA; bis-(trimethylsilyl) trifluoroacetamide; CAT; catalase; EEP; ethanol extract of propolis; E. coli; bacterium Staphylococcus aureus; C. albicans; fungus Candida al

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Development of phosphocellulose paper-based screening of inhibitors of lipid kinases: Case study with PI3Kβ

Keywords: Phosphatidyl inositol 3-kinase; Phosphocellulose; Lipid; PtdIns; PtdSer; IC50

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitors

Keywords: EZH2; enhancer of zeste homologue 2; ELISA; enzyme-linked immunosorbent assay; IC50; half maximal inhibitory concentration; GI50; half maximal growth-inhibitory concentration; Ki; dissociation constant of the enzyme-inhibitor complex; EED; embryonic ect

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Synthetically modified l-histidine-rich peptidomimetics exhibit potent activity against Cryptococcus neoformans

Keywords: AA; amino acid; Boc; tert-butoxycarbonyl; DIC; 1,3-diisopropylcarbodiimide; DIEA; N,N-diisopropylethylamine; EYPC; egg yolk l-a-phosphatidylcholine; DMF; N,N-dimethylformamide; EYPG; egg yolk l-a-phosphatidyl-dl-glycerol; TBTU; O-(benzotriazol-1-yl)-N,N,N

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of the proteins related to SET-mediated hepatic cytotoxicity of trichloroethylene by proteomic analysis

Keywords: TCE; trichloroethylene; FBS; fetal bovine serum; PBS; phosphate buffered saline; CBB; Coomassie Brilliant Blue; IEF; isoelectric focusing; IPG; immobilized pH gradient; PMF; peptide mass fingerprinting; DTT; dithiothreitol; DIGE; difference gel electropho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Green tea epigallocatechin gallate binds to and inhibits respiratory complexes in swelling but not normal rat hepatic mitochondria

Keywords: EGCG; epigallocatechin gallate; RCCs; respiratory chain complexes; MPT; mitochondrial permeability transition; IM; inner membranes; SDHA; succinate dehydrogenase complex, subunit A; SDHB; succinate dehydrogenase complex, subunit B; SDHC; succinate dehydro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Tritium-labelled isovaleryl-RYYRIK-NH2 as potential antagonist probe for ORL1 nociceptin receptor

Keywords: Boc; butoxycarbonyl; Bmax; receptor density; DMEM; Dulbecco's Modified Eagle's Medium; DMF; N,N-dimethylformamide; FBS; fetal bovine serum; GPCR; G protein-coupled receptor; HBTU; 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Hepatitis B virus replication is blocked by a 2-hydroxyisoquinoline-1,3(2H,4H)-dione (HID) inhibitor of the viral ribonuclease H activity

Keywords: HBV; hepatitis B virus; CHB; chronic hepatitis B; NA; nucleos(t)ide analogs; RNaseH; ribonuclease H; HIV; human immunodeficiency virus; HID; 2-hydroxyisoquinoline-1,3(2H,4H)-dione compounds; DMSO; dimethyl sulfoxide; IC50; 50% inhibitory concentration; MT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

FLLL31, a derivative of curcumin, attenuates airway inflammation in a multi-allergen challenged mouse model

Keywords: STAT; signal transducer and activator of transcription; JAK; Janus kinase; LPS; lipopolysaccharide; Con A; concanavalin A; HDM; house dust mite; PBS; phosphate-buffered saline; NO; nitric oxide; Dex; dexamethasone; TNF-α; tumor necrosis factor α; IL; in

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

L-type Ca2+ channel blockers inhibit the window contraction of mouse aorta segments with high affinity

Keywords: Nifedipine (PubChem CID: 4485); Amlodipine (PubChem CID: 2162); Diltiazem HCl (PubChem CID: 62920); Verapamil HCl (PubChem CID: 62969); BAY K8644 (PubChem CID: 2303); Vascular reactivity; L-type calcium channel; Calcium channel blocker; Depolarization; Co

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

Keywords: AP(D); action potential (duration); AZ; AstraZeneca; B&Q2; IonWorks Barracuda and second Quattro screening dataset; GLP; good laboratory practice; GSK; GlaxoSmithKline; IC50; concentration for 50% inhibition; ICaL; long-lasting-type calcium current; IKr;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand

Keywords: ABC-transporter; ATP-binding cassette transporter; BBB; blood-brain barrier; Calcein-AM; calcein acetoxymethylester; EC50; 50% effective concentration; ECmax; maximal effective concentration; HPLC; high pressure liquid chromatography; IC50; 50% inhibito

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

Keywords: HPPK; 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; DHP; 6-hydroxymethyl-7,8-dihydropterin; DHPS; dihydropteroate synthase; SPR; surface plasmon resonance; KD; equilibrium dissociation constant; IC50; half maximal inhibitory concentration; AMPCPP;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Design, synthesis and biological evaluation of new 5-nitro benzimidazole derivatives as AT1 antagonists with anti-hypertension activities

Keywords: RAS; rennin-angiotensin system; AII; angiotensin II; ARBs; angiotensin II receptor blockers; FDA; US Food and Drug Administration; DMAP; 4-(dimethylamino)pyridine; NMR; nuclear magnetic resonance; HRMS; high-resolution mass spectrometry; ESI; electrospr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Transition metal complexes of a new 15-membered [N5] penta-azamacrocyclic ligand with their spectral and anticancer studies

Keywords: Penta-azamacrocyclic; Macrocyclic metal complexes; Spectral studies; Antitumor activity; IC50

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of coregulators influenced by estrogen receptor subtype specific binding of the ER antagonists 4-hydroxytamoxifen and fulvestrant

Keywords: 4OHT; 4-hydroxytamoxifen; ATP; adenosine triphosphate; BSA; bovine serum albumin; CCD; charge coupled device; CDTA; 1,2-diaminocyclohexanetetraacetic acid monohydrate; DCC-FCS; dextran-coated charcoal-treated fetal calf serum; DMEM; Dulbecco's modified

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Purification and characterization of a novel antitumor protein with antioxidant and deoxyribonuclease activity from edible mushroom Pholiota nameko

Keywords: Pholiota nameko; Purification; Antioxidant; Deoxyribonuclease; Antitumor; Apoptosis; PNAP; Pholiota nameko antitumor protein; DPPH; 1,1-diphenyl-2-picrylhydrazyl; BHA; butylated hydroxy anisole; DNase; deoxyribonuclease; DAPI; 4′,6-diamidino-2-phenyl-in

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ERα and ERβ agonists

Keywords: ATP; adenosine triphosphate; BrdU; 5-bromo-2′-deoxyuridine; BSA; bovine serum albumin; CCD; charge coupled device; CDTA; 1,2-diaminocyclo-hexanetetraacetic acid; CHO; Chinese hamster ovary; DCC-FCS; dextran-coated charcoal-treated fetal calf serum; DMEM

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

P21-activated kinase in inflammatory and cardiovascular disease

Keywords: AID; Auto-inhibitory domain; ATP; Adenosine-triphosphate; B-cell; B lymphocytes; BLNK; B cell linker protein; CaM; Calmodulin; Cdc; Cell division control protein; cyt b558; Flavocytochrome b558; DUOX1/2; Dual oxidase 1/2; EF hand motif; Helix-loop-helix s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Role of glutamine-169 in the substrate recognition of human aminopeptidase B

Keywords: APB; aminopeptidase B; IC50; half maximal (50%) inhibitory concentration; EC50; half maximal (50%) effective concentration; ERAP; endoplasmic reticulum aminopeptidase; LTA4H; leukotriene A4 hydrolase; MCA; 4-methylcoumaryl-7-amide; NRD; N-arginine dibasic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Polyphenol composition, antioxidant and bioplaguicide activities of the solid residue from hydrodistillation of Rosmarinus officinalis L.

Keywords: A.U.; absorbance units; CPB; Colorado potato beetle; DPPH; 2,2-diphenyl-1-picrylhydrazyl; FI; feeding inhibition; SI; settling inhibition; IC50; 50% inhibition concentration; PV; pyrocatechol violet; ROS; reactive oxygen species; Antifeedant; Aromatic pla

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition

Keywords: CYP; cytochrome P450; UGT; UDP-glucuronosyltransferase; S-Rg3; 20(S)-ginsenoside Rg3; R-Rg3; 20(R)-ginsenoside Rg3; S-Rh2; 20(S)-ginsenoside Rh2; R-Rh2; 20(R)-ginsenoside Rh2; NADP+; β-nicotinamide adenine dinucleotide phosphate; LC-MS/MS; liquid chrom

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena

Keywords: HWTX-XVI; Tarantula toxin; N-type calcium channels; Dorsal root ganglia; Rat vas deferens; Pain model; Analgesic action; HWTX; Huwentoxin; ICK; inhibitor cystine knot; Cav channel; voltage-gated calcium channel; Nav channel; voltage-gated sodium channel;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Hydroxychavicol, a betel leaf component, inhibits prostate cancer through ROS-driven DNA damage and apoptosis

Keywords: ROS; reactive oxygen species; HC; hydroxychavicol; BLE; betel leaf extract; FBS; fetal bovine serum; ATCC; American type cell culture; MTT; tetrazolium bromide solution; DNA; deoxyribonucleic acid; LC3-IIb; light chain 3-IIb; DMSO; dimethylsulfoxide; IC50

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Hollow microspheres based on - Folic acid modified - Hydroxypropyl Cellulose and synthetic multi-responsive bio-copolymer for targeted cancer therapy: Controlled release of daunorubicin, in vitro and in vivo studies

Keywords: Drug delivery systems; Folic acid; Multi responsive carriers; HPC; Polysaccharides; Daunorubicin; Microspheres; Cytotoxicity; IC50; MTT assay;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Pyrazole derivatives as potent inhibitors of c-Jun N-terminal kinase: Synthesis and SAR studies

Keywords: JNK-1; Inflammation; Pyrazoles; IC50;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Antitumoural and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models

Keywords: CAM; chicken chorioallantoic membrane; CAPE; caffeic acid phenethyl ester; BrdU; 5-bromo-2′-deoxyuridine; HPLC-MSn; high-performance liquid chromatography-mass spectrometry; IC50; half maximal inhibitory concentration; P10.EE; ethanolic extract (EE) of

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Antisense oligonucleotides on neurobehavior, respiratory, and cardiovascular function, and hERG channel current studies

Keywords: ASO; Antisense Oligonucleotide; CNS; Central Nervous System; ECG; Electrocardiography; FOB; Functional Observatory Battery; GLP; Good Laboratory Practice; hERG; Human Ether-a-go-go related gene; ICH; International Conference on Harmonisation; IC50; The ha

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه