Novel SNPs in IGF1, GHR and IGFBP-3 genes reveal significant association with growth traits in Indian goat breeds
Keywords: IGF-1; GHR and IGFBP-3; SNP; Jamunapari; Sirohi; Goat;
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Combination of bendamustine and entinostat synergistically inhibits proliferation of multiple myeloma cells via induction of apoptosis and DNA damage response
Keywords: MM; Multiple myeloma; CLL; chronic lymphocytic leukemia; HDAC; histone deacetylase; HDACi; Inhibitor of HDAC; HAT; Histone acetyltransferase; PARP; poly(ADP-ribose) polymerase; ELISA; enzyme-linked immunosorbent assay; PAGE; polyacrylamide gel electrophor
Synthesis and biological activity of 5-chloro-N4-substituted phenyl-9H-pyrimido[4,5-b]indole-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic agents
Keywords: ATP; adenosine 5â²triphosphate; VEGF; vascular endothelial growth factor; EGF; epidermal growth factor; PDGF; platelet derived growth factor; RTK; receptor tyrosine kinase; VEGFR-2; vascular endothelial growth factor receptor-2; VEGFR-1; vascular endothe
Increased serum sclerostin and decreased serum IGF-1 are associated with vertebral fractures among postmenopausal women with type-2 diabetes
Keywords: Sclerostin; IGF-1; Bone turnover markers; Diabetes; Postmenopausal women;
A dose finding, safety and pharmacokinetic study of AVE1642, an anti-insulin-like growth factor-1 receptor (IGF-1R/CD221) monoclonal antibody, administered as a single agent and in combination with docetaxel in patients with advanced solid tumours
Keywords: IGF-1R; Monoclonal antibody; Sarcoma; Breast cancer; IGF-1;
FoxO regulates expression of ABCA6, an intracellular ATP-binding-cassette transporter responsive to cholesterol
Keywords: IGF-1; insulin-like growth factor-1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; PI3K; phosphatidylinositol 3-kinase; CHO; Chinese hamster ovary; FITC; fluorescein isothiocyanate; TRITC; tetramethylrhodamine isothiocyanate; DTT; dithiothreitol; ABC t
Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth
Keywords: BBR; Berberine; Bcl-2; B-cell lymphoma 2; HO-1; Hemeoxygenase-1; IGF-1; Insulin growth factor-1; LDH; Lactate dehydrogenase; MTT; 3-(4,5-dimethyl- thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide; NGF; Nerve growth factor; Nrf2; Nuclear erythroid 2-related
Role of estrogen receptor-α (ESR1) and the type 1 insulin-like growth factor receptor (IGFR1) in estradiol-stimulated proliferation of cultured bovine satellite cells
Keywords: Estradiol; Estrogen receptor-α; type 1 insulin-like growth factor receptor; Bovine satellite cells; IGF-1;
Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer
Keywords: AP-1; activator protein-1; BrdU; 5-bromo-2â²-deoxyuridine; ChIP; chromatin immunoprecipitation; dcSAMe; decarboxylated SAMe; EGF; epidermal growth factor; HCC; hepatocellular carcinoma; HPLC; high-performance liquid chromatography; IGF-1; insulin-like gr
Schwann cell phenotype is regulated by axon modality and central-peripheral location, and persists in vitro
Keywords: BDNF; brain derived neurotrophic factor; CNTF; ciliary neurotrophic factor; FGF-2; fibroblast growth factor 2; GDNF; glial cell line derived neurotrophic factor; HGF; hepatocyte growth factor; IGF-1; insulin-like growth factor 1; IGF-2; insulin-like growt
VEGF but not PlGF disturbs the barrier of retinal endothelial cells
Keywords: retinal endothelial cells; VEGF; PlGF; bFGF; IGF-1; ranibizumab; aflibercept; diabetic macular edema; bFGF; basic fibroblast growth factor; (i)BREC; (immortalized) bovine retinal endothelial cells; DME; diabetic macular edema; DR; diabetic retinopathy; EC
Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: Potential therapeutic targets for cardiac cachexia
Keywords: Ang II; angiotensin II; AT1R; angiotensin II type 1 receptor; CHF; congestive heart failure; ESRD; end-stage renal disease; ACE; angiotensin-converting enzyme; UPS; ubiquitin proteasome system; ROS; reactive oxygen species; IGF-1; insulin-like growth fact
Endogenous CNTF mediates stroke-induced adult CNS neurogenesis in mice
Keywords: BDNF; brain-derived neurotrophic factor; BrdU; 5-bromo-2â²-deoxyuridine; CC; corpus callosum; CD45; cluster of differentiation number 45 or leukocyte common antigen; CNTF; ciliary neurotrophic factor; Dll3; delta-like 3; ECA; external carotid artery; EGF
Regulation of Akt-mTOR, ubiquitin-proteasome and autophagy-lysosome pathways in response to formoterol administration in rat skeletal muscle
Keywords: Actb; actin beta; Atg; autophagy-related; Bnip3; BCL2/adenovirus E1B interacting protein 3; BSA; bovine serum albumin; COPD; chronic obstructive pulmonary disease; CREB; cAMP response element binding protein; EDL; extensor digitorum longus; eIF3-f; eukary
Cytokines from the tumor microenvironment modulate sirtinol cytotoxicity in A549 lung carcinoma cells
Keywords: Tumor microenvironment; SIRT1; TRAIL; IGF-1; Necroptosis; TRAIL; TNF related apoptosis inducing ligand; SIRT1; sirtuin1; IGF-1; insulin-like growth factor-1; iNOS; inducible nitric oxide synthase; TNF-α; tumor necrosis factor α; TGF-β; transforming gro
Metformin and Sulfonylureas in Relation to Cancer Risk in Type II Diabetes Patients: A Meta-analysis using primary data of published studies
Keywords: T2DM; type 2 diabetes mellitus; RCTs; randomized control trials; RR; relative risk; OR; odds ratio; 95% CI; 95% confidence interval; NIH; National Institutes of Health; IGF-1; insulin like growth factor-1; PRISMA; Preferred Reporting Items for Systematic
Switching from MAPK-dependent to MAPK-independent repression of the sodium-iodide symporter in 2D and 3D cultured normal thyroid cells
Keywords: EGF; epidermal growth factor; EMT; epithelial to mesenchymal transition; ERK1/2; extracellular-signal regulated kinase 1/2; FBS; fetal bovine serum; IGF-1; insulin-like growth factor-1; LY294002; PI3K inhibitor; MAPK; mitogen-activated protein kinase; MEK
The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer
Keywords: Growth hormone; IGF-1; Antidiabetic biguanides; Aging; Cancer prevention;
Acromegaly
Keywords: acromegaly; GH; IGF-1; pituitary
Association between dietary folate intake and serum insulin-like growth factor-1 levels in healthy old women
Keywords: Folates; IGF-1; Old people; Mediterranean diet
Positive effects of aerobic exercise on learning and memory functioning, which correlate with hippocampal IGF-1 increase in adolescent rats
Keywords: Exercise; Hippocampus; IGF-1; Spatial learning and memory; Adolescent
Retentissement osseux de l’anorexie mentale
Keywords: Ostéoporose; Anorexie mentale; IGF-1; Marqueurs osseuxOsteoporosis; Anorexia nervosa; IGF-1; Bone remodeling markers
Decreased IGF-1 levels potentiate association of inflammation with all-cause and cardiovascular mortality in prevalent hemodialysis patients
Keywords: IGF-1; IL-6; Inflammation; Hemodialysis; Survival
Delays in Puberty, Growth, and Accrual of Bone Mineral Density in Pediatric Crohn's Disease: Despite Temporal Changes in Disease Severity, the Need for Monitoring Remains
Keywords: BMD; Bone mineral density; CD; Crohn's disease; IBD; Inflammatory bowel disease; IGF-1; Insulin-like growth factor 1; UC; Ulcerative colitis;
Nutrition, insulin-like growth factor-1 and retinopathy of prematurity
Keywords: IGF-1; Nutrition; Omega-3; Retinopathy of prematurity
Sex-dependent insulin like growth factor-1 expression in preattachment equine embryos
Keywords: Horse; Embryo; IGF-1; Sex difference
Glucose metabolism disorder is a risk factor in ethanol exposure induced malformation in embryonic brain
Keywords: Ethanol toxicity; Glucose metabolism; Chicken embryo; GLUT1; IGF-1
Revisiting the timing hypothesis: Biomarkers that define the therapeutic window of estrogen for stroke
Keywords: Estrogen therapy; IGF-1; MicroRNA; Stroke; Vitamin D
Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats
Keywords: Aging; Skeletal muscle; Resistance exercise training; Autophagy; Apoptosis; IGF-1; Akt/mTOR; Akt/FOXO3a
Growth hormone (GH) and brain trauma
Keywords: TBI; GH; IGF-1; Cognitive disorders; Neurogenic dysphagia; Hemi/tetraplegia; Amaurosis; Physiotherapy; Visual stimulation; Remyelination
Actualités dans le traitement étiologique de la sclérose latérale amyotrophique
Keywords: sclérose latérale amyotrophique; neurologie; motoneurone; traitement; survie; amyotrophic lateral sclerosis; neurology; motoneuron; treatment; survival; AALSRS; appel ALS rating scale; ALSFRS; amyotrophic lateral sclerosis functional rating scale; AMM;
The Biology of Retinopathy of Prematurity
Keywords: Oxygen; IGF-1; Omega-3 polyunsaturated fatty acids; Postnatal weight gain; Erythropoietin;
Lymphocyte GH-axis hormones in immunity
Keywords: Growth hormone; Lymphocytes; Growth hormone releasing hormone; IGF-1
A New p53 Target Gene, RKIP, Is Essential for DNA Damage-Induced Cellular Senescence and Suppression of ERK Activation
Keywords: Adr; adriamycin; Etop; etoposide; IGF-1; insulin-like growth factor 1;
A novel automated bioreactor for scalable process optimisation of haematopoietic stem cell culture
Keywords: HSCs; haematopoietic stem cells; ambrâ¢; advanced microscale bioreactor; rpm; revolutions per minute; μ; mean; SEM; standard error of the mean; FITC; Fluorescein isothiocyanate; dO2; dissolved oxygen; ANOVA; analysis of variance; SCF; stem cell factor;
IGF-1 prevents oxidative stress induced-apoptosis in induced pluripotent stem cells which is mediated by microRNA-1
Keywords: iPS cells; IGF-1; microRNA; Apoptosis; Cytochrome-c; Mitochondria
Serum levels of leptin, adiponectin and resistin are interrelated and related to total antioxidant capacity, free fatty acids and phospholipids in early neonatal life
Keywords: Leptin; Adiponectin; Resistin; Infants; Total antioxidant capacity; IGF-1; Phospholipids
Evaluation of the Bone Status in High-Level Cyclists
Keywords: Bone mineral density; highly trained cyclists; IGF-1; vitamin D;
Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells
Keywords: IGF-1; PRAS40; PI3K/Akt; MAPK; Neuronal cells survival;
A Pilot Study of Discontinuous, Insulin-Like Growth Factor 1-Dosing Growth Hormone Treatment in Young Children with FGFR3 N540K-Mutated Hypochondroplasia
Keywords: GH; Growth hormone; IGF-1; Insulin-like growth factor 1; L4/L1; Ratio of interpedicular distances at the fourth and first lumbar vertebrae; rGH; Recombinant growth hormone; SHR; Sitting height-to-height ratio;
Reduced levels of serum IGF-1 is related to the presence of osteoporotic fractures in male idiopathic osteoporosis
Keywords: IGF-1; Male idiopathic osteoporosis; Sex hormones; Fractures; Bone mineral density
La baisse des taux d’IGF-1 sérique est corrélée à la présence de fractures ostéoporotiques lors de l’ostéoporose masculine idiopathique
Keywords: IGF-1; Ostéoporose masculine idiopathique; Hormones sexuelles; Fractures; Densité minérale osseuse
Treatment with Recombinant Human Growth Hormone during Childhood is Associated with Increased Intraocular Pressure
Keywords: GH; Growth hormone; GHD; Growth hormone deficiency; IGF-1; Insulin-like growth factor 1; IOP; Intraocular pressure; ISS; Idiopathic short stature; rhGH; Recombinant human growth hormone; SGA; Small for gestational age;
A novel treatment for vestibular disorder with FGLM-NH2 plus SSSR
Keywords: SP; substance P; NK-1; neurokinin-1; FGLM-NH2; Phenylalanine-Glycine-Leucine-Methionine-Amide; SSSR; Serine-Serine-Serine-Arginine; IGF-1; insulin-like growth factor; AMPA; (±)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; VOR gain
Induction of somatic growth in juvenile crayfish Cherax quadricarinatus (Decapoda, Parastacidae), by ecdysone and insulin growth factor
Keywords: Crayfish; Somatic growth; Ecdysone; IGF-1; Protein synthesis; Energetic reserves
Anxiety correlates to decreased blood and prefrontal cortex IGF-1 levels in streptozotocin induced diabetes
Keywords: Diabetes; Anxiety; IGF-1; SOD; MDA; Corticosterone; Prefrontal cortex
Expression of insulin-like growth factor-1 of orange-spotted grouper (Epinephelus coioides) in yeast Pichia pastoris
Keywords: IGF-1; Orange-spotted grouper; Pichia pastoris; Proliferation
Original Full Length ArticleTrabecular bone histomorphometry in humans with Type 1 Diabetes Mellitus
Keywords: DM; Diabetes Mellitus; BMI; body mass index; GAD; glutamic acid decarboxylase; HgA1c; glycated hemoglobin; GFR; glomerular filtration rate; DXA; dual energy X-ray absorptiometry; BMD; bone mineral density; 25(OH)D; 25-hydroxyvitamin D; IGF-1; insulin like
Diosgenin induces apoptosis in IGF-1-stimulated human thyrocytes through two caspase-dependent pathways
Keywords: Diosgenin; Apoptosis; Primary human thyrocytes; IGF-1; Caspase-dependent pathways
Using high resolution melting analysis to identify variation of NPY, LEP and IGF-1 genes in Angus cattle
Keywords: HRM; SNPs; NPY; Leptin; IGF-1; Angus breed;